Articles tagged "Renal function"

2016 American Transplant Congress
Evaluation According to Donor Source: 24-Month Results from Post-Hoc Analysis of the ELEVATE Study in Kidney Transplant Recipients.
J. de Fijter, H. Holdaas, P. Lopez, P. Bernhardt, D. Gaohong, J. Cruzado, M. van der Giet.
ELEVATE study group, Leiden, Netherlands.
Background: Several studies reported that recipients receiving renal allograft from living donors have better efficacy outcomes than the deceased donor counterparts. This post-hoc analysis of…
2016 American Transplant Congress
Efficacy and Renal Function in Kidney Transplant Recipients Receiving Tacrolimus (TAC)-Based Immunosuppressive Regimens in Combination with Everolimus (EVR) versus Mycophenolate (MPA).
A. Brigido, H. Tedesco, C. Felipe, M. Cristelli, M. Franco, J. Medina-Pestana.
Nephrology Division, Hospital do Rim - UNIFESP, Sao Paulo, Brazil.
Acute rejection and renal function are associated with long-term renal allograft survival. We evaluated these outcomes in patients receiving reduced TAC exposure combined with EVR…
2016 American Transplant Congress
Comparison of Transplant Outcomes for Low-Dose and Standard-Dose Tacrolimus in Kidney Transplant Recipients.
J.-H. Cho, K. Kim, M. Kim, W. Do, Y. Yang, T. Yim, I. Hwang, J.-H. Lee, E. Kwon, H.-Y. Jung, J.-Y. Choi, S.-H. Park, Y.-L. Kim, C.-D. Kim.
Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
Objectives: There are few studies that compare the effect of different dose of tacrolimus after kidney transplantation. We investigated transplant outcome of low-dose and standard-dose…
2016 American Transplant Congress
Evaluation of the Long-Term Outcomes with Everolimus After Calcineurin Inhibitor Withdrawal: 36M Results of the H2304 and PROTECT Extension Studies.
L. Fischer,^1,2 J. Fung,¹ H. Metselaar,¹ G. Kaiser,^1,2 P. Schemmer,² P. Neuhaus,² G. Dong,³ P. Lopez,⁴ P. Bernhardt,⁴ H. Schlitt.²
¹H2304 study group, Hamburg, Germany; ²PROTECT study group, Hamburg, Germany; ³Novartis Pharmaceuticals Corporation, East Hanover, NJ; ⁴Novartis Pharma AG, Basel, Switzerland.
Background: The H2304 and PROTECT studies demonstrated reduced nephrotoxicity with everolimus (EVR)-based calcineurin inhibitor (CNI; cyclosporine: CsA, tacrolimus: TAC)-free regimens at Month (M) 12. Here,…
2016 American Transplant Congress
TRANSFORM: A Modern Approach to Evaluate Long-Term Outcomes of Everolimus with Reduced-Calcineurin Inhibitors in De Novo Kidney Transplant Recipients[mdash]Baseline Characteristics.
M. Henry.
On behalf of the TRANSFORM Investigators, Division of Transplantation Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH.
Purpose: Acute rejection and poor graft function are two major risk factors for allograft failure in kidney transplant (KTx) recipients (KTxR). Although, graft survival and…
2016 American Transplant Congress
Impact on Renal Function of Stepwise Withdrawal of Tacrolimus Combined with Everolimus and EC-MPS vs Standard Treatment Combining Tacrolimus and EC-MPS in De Novo Liver Transplant Recipients: Results of the SIMCER Study.
F. Saliba,¹ C. Duvoux,² S. Dharancy,³ J. Dumortier,⁴ Y. Calmus,⁵ F. Di Giambattista,⁶ F. Conti.⁵
¹Hôpital Paul Brousse, Villejuif, France; ²Hôpital Henri Mondor, Créteil, France; ³Hôpital Claude Huriez, Lille, France; ⁴Hôpital Edouard Herriot, Lyon, France; ⁵Hôpital La Pitié-Salpêtrière, Paris, France; ⁶Novartis Pharma SAS, Rueil-Malmaison, France.
Introduction: Long-term post-liver transplant (LTx) complications, particularly impaired renal function (RF) and its consequences, remain a concern. Presented here are the results of the SIMCER…
2016 American Transplant Congress
The Importance of KDPI in Simultaneous Liver and Kidney Transplant.
E. Chan,¹ M. Hertl,¹ J. Perkins.²
¹General Surgery, Rush University Medical Center, Chicago, IL; ²Surgery, University of Washington, Seattle, WA.
Background: The use of the Donor Risk Index (DRI) in liver transplantation and the Kidney Donor Profile Index (KDPI) in kidney transplantation has been well…
2016 American Transplant Congress
Short-Term Post-Donation Renal Function in Living Kidney Donors.
L. Fahmy, A. Massie, A. Muzaale, S. Sandal, E. Chow, D. Segev.
JHU, Baltimore.
Previous single-center studies of post-donation estimated glomerular filtration rate (eGFR) in living kidney donors were limited by small sample size and lack of generalizability. The…
2016 American Transplant Congress
Comparing Renal Function After Liver Transplantation: Modified Piggyback versus Conventional Techniques without Venovenous Bypass.
J. Lee, J. Lee, S. Song, J. Lee, S.-K. Kwon, D. Han, M. Ju, G. Choi, J. Choi, M. Kim, S. Kim, D. Joo.
Surgery, Yonsei University College of Medicine, Seoul, Korea.
BackgroundThere are several options available for caval reconstruction in liver transplantation. Prior reports demonstrated that caval reconstruction technique could affect the renal function. However, there…
2016 American Transplant Congress
Impact of Donor-Recipient Relationship on Development of CKD.
A. Matas, D. Vock, H. Ibrahim.
UMN, Mpls, MN.
Two studies have reported a small increase of ESRD in LDs compared to healthy matched controls. However, the majority of ESRD has been in relatives…