ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal function"

  • 2017 American Transplant Congress

    Effect of Everolimus-Based Regimen on Graft Outcomes in Kidney Transplant Recipients with Diabetes at Baseline: Post-Hoc Analysis from the ELEVATE Study.

    J. de Fijter,1 H. Holdaas,1 J. Sanders,1 S. Sundar,1 F. Bemelman,1 P. Lopez,2 G. Bader,2 J. Cruzado,1 M. van der Giet.1

    1ELEVATE Study Group, Leiden, Netherlands; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: Presence of diabetes may have adverse impact on graft outcome in kidney transplant recipients (KTxRs). This post-hoc analysis from the ELEVATE study compared the…
  • 2017 American Transplant Congress

    Short-Term Adverse Effects of Early Borderline Changes in Renal Allograft Biopsies.

    S. Bhusal, P. Sood, A. Cherukuri, C. Wu, C. Puttarajappa, W. Hoffman, P. Randhawa, A. Tevar, N. Shah, S. Hariharan, R. Mehta.

    Department of Medicine and Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA

    Background: The short and long-term impact of borderline changes noted on renal allograft biopsies remains unclear.Methods: A total of 379 patients underwent renal transplantation at…
  • 2017 American Transplant Congress

    Predicting Residual Renal Compensation in Living Kidney Donors Post-Donation.

    A. Diez, G. Diltz, J. Von Visger, U. Nori, T. Pesavento, R. Pelletier.

    Ohio State University College of Medicine, Columbus, OH

    In living kidney donors it is well established that post-donation the remaining kidney undergoes functional hypertrophy; resulting in a 20% – 40% in increase in…
  • 2017 American Transplant Congress

    Comparison of Long Term Renal Function Outcomes for Everolimus (EVR) vs. Sirolimus (SIR) vs. Mycophenolate Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant (Ktx).

    H. Tedesco,1 W. Irish,2 K. Dharmesh,3 D. Patel,3 D. Cibrik.4

    1Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2CTI Consulting, Raleigh; 3Novartis Pharmaceuticals Corporation, East Hanover; 4University of Michigan, Ann Arbor

    MPA or mammalian target of rapamycin inhibitors (mTORi [EVR or SIR]) in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine) are used for maintenance…
  • 2016 American Transplant Congress

    Impact of Donor-Recipient Relationship on Development of CKD.

    A. Matas, D. Vock, H. Ibrahim.

    UMN, Mpls, MN.

    Two studies have reported a small increase of ESRD in LDs compared to healthy matched controls. However, the majority of ESRD has been in relatives…
  • 2016 American Transplant Congress

    Comparison of Clinical Outcomes of Belatacept- and Tacrolimus-Based Immunosuppression in Renal Transplant Recipients.

    X. Wen,1 M. Casey,1 A. Santos,1 A. Hartzema,2 K. Womer.1

    1Department of Medicine, University of Florida, Gainesville, FL; 2Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, FL.

    To examine the utilization and clinical outcomes of belatacept in the real clinical setting, a retrospective cohort study was conducted using SRTR data that compared…
  • 2016 American Transplant Congress

    Dual Kidney Transplants as Policy to Optimize the Allocation of Marginal Donor Kidneys: Analysis of the French Cohort Since 2002.

    E. Savoye,1 R. Snanoudj,2 C. Hiesse,3 M.-N. Peraldi,4 A. Durrbach,5 N. Ouali,6 M. Durand,7 L. Badet,8 M.-A. Macher.1

    1Agence de la Biomédecine, Saint Denis, France; 2Necker hospital, Paris, France; 3Foch hospital, Suresnes, France; 4Saint Louis Hospital, Paris, France; 5Bicêtre Hospital, Kremlin Bicetre, France; 6Tenon hospital, Paris, France; 7Pasteur hospital Nice, Nice, France; 8Department of Chirurgie de la Transplantation Pav V and Department of Immunologie Clinique Transplantation Pav P, Edouard Herriot Hospital Group, Lyon, France.

    The aim of this national multicentre cohort study was to assess the safety of dual kidney transplantation (DKT) in terms of patient and graft survival…
  • 2016 American Transplant Congress

    Kidney Structural Characteristics as Predictors of Long-Term Kidney Function in Living Kidney Donors.

    J. Mathew,1 A. Denic,1 M. Alexander,2 T. Vrtiska,3 H. Chakkera,4 S. Taler,1 A. Rule.1

    1Nephrology, Mayo Clinic, Rochester, MN; 2Pathology, Mayo Clinic, Rochester, MN; 3Radiology, Mayo Clinic, Rochester, MN; 4Nephrology, Mayo Clinic, Scottsdale, AZ.

    PurposeKidney structural characteristics may be predictive of long-term living donor outcomes such as a lower estimated Glomerular Filtration Rate (eGFR).MethodsAs part of the Renal and…
  • 2016 American Transplant Congress

    Creation of a Small Animal Model of Ex-Vivo Normothermic Perfusion (EVNP) for Treatment of Kidney Ischemia-Reperfusion (I/R) Injury.

    Y. Smolin, I. Palma, C. Pivetti, S. Kabagambe, J. Woloszyn, Y. Chen, T. Boyer, I. Palma, J. Sageshima, C. Santhanakrishnan, R. Perez.

    Department of Surgery, UC Davis Medical Center, Sacramento, CA.

    Purpose: Recent studies have suggested that EVNP may be utilized to assess and repair marginal donor organs subjected to severe I/R injury. The lack of…
  • 2016 American Transplant Congress

    Standardized Pre-Implantation Kidney Biopsies of Expanded Criteria Donors to Improve the Kidney Donor Profile Index (KDPI) for the Evaluation of Marginal Donors.

    A. Sánchez-Escuredo,1 A. Sagasta,2 F. Diekmann,1 I. Revuelta,1 L. Rodas,1 D. Paredes,3 M. Musquera,4 N. Esforzado,1 M. Ricart,1 F. Cofan,1 V. Torregrosa,1 J. Campistol,1 M. Sole,2 F. Oppenheimer.1

    1Nephrology and Renal Transplant, Hospital Clínic, Barcelona, Spain; 2Pathology, Hospital Clínic, Barcelona, Spain; 3Transplant Foundation, Hospital Clínic, Barcelona, Spain; 4Urology, Hospital Clínic, Barcelona, Spain.

    There is no consensus of selection criteria used to allocate renal transplants from expanded criteria donors (ECD). The Kidney Donor Profile Index (KDPI) has been…
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