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Articles tagged "Renal function"

  • 2017 American Transplant Congress

    Predicting Residual Renal Compensation in Living Kidney Donors Post-Donation.

    A. Diez, G. Diltz, J. Von Visger, U. Nori, T. Pesavento, R. Pelletier.

    Ohio State University College of Medicine, Columbus, OH

    In living kidney donors it is well established that post-donation the remaining kidney undergoes functional hypertrophy; resulting in a 20% – 40% in increase in…
  • 2017 American Transplant Congress

    Comparison of Long Term Renal Function Outcomes for Everolimus (EVR) vs. Sirolimus (SIR) vs. Mycophenolate Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant (Ktx).

    H. Tedesco,1 W. Irish,2 K. Dharmesh,3 D. Patel,3 D. Cibrik.4

    1Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2CTI Consulting, Raleigh; 3Novartis Pharmaceuticals Corporation, East Hanover; 4University of Michigan, Ann Arbor

    MPA or mammalian target of rapamycin inhibitors (mTORi [EVR or SIR]) in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine) are used for maintenance…
  • 2017 American Transplant Congress

    Influence of Donor-Specific Antibodies on Renal Function in Kidney Transplant Recipients Following Early Switch from Calcineurin Inhibitor to Everolimus: Subanalysis from the ELEVATE Study.

    J. Cruzado,1 H. Holdaas,1 P. Lopez,2 P. Bernhardt,2 G. Bader,2 F. Claas,1 W. Arns,1 M. van der Giet,1 J. de Fijter.1

    1ELEVATE Study Group, Llobregat Catalunya, Spain; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: The development of donor-specific antibody (DSA) is a known risk factor for poor graft outcomes after kidney transplantation (KTx). Previous analysis of the ELEVATE…
  • 2017 American Transplant Congress

    Donor Kidney Volume Predicts One and Three Month eGFR in Live Donor Kidney Transplant Recipients.

    D. Al-Adra,1 M. Lambadaris,2 A. Barbas,1 Y. Li,2 N. Goldaracena,1 O. Famure,2 S. Kim,2 A. Ghanekar.1

    1Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 2Kidney Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    IntroductionThere has been increasing interest in non-immunological factors that may impact long-term graft survival after kidney transplantation. It is hypothesized that transplantation of larger nephron…
  • 2017 American Transplant Congress

    Steroid Withdrawal Using Everolimus in Maintenance Kidney Transplant Recipients with Post-Transplant Diabetes Mellitus.

    K. Nanmoku, A. Kurosawa, T. Kubo, T. Shinzato, T. Shimizu, T. Kimura, T. Yagisawa.

    Surgical Branch, Institute of Kidney Diseases, Jichi Medical University Hospital, Shimotsuke, Tochigi, Japan

    Background: Although steroid withdrawal from conventional immunosuppressive therapy has been attempted to ameliorate various complications, especially diabetes mellitus (DM), in kidney transplant recipients, a steroid-sparing…
  • 2017 American Transplant Congress

    Repeat Biopsies After the Diagnosis of BK Virus Associated Nephropathy: Importance of Integrating Clinical and Pathological Findings.

    C. Drachenberg,1 J. Papadimitriou,1 R. Ugarte,2 M. Mavanur,2 B. Thomas,2 C. Cangro,2 N. Costa,2 M. Weir,2 A. Haririan.2

    1Pathology, University of Maryland School of Medicine, Baltimore, MD; 2Medicine, University of Maryland School of Medicine, Baltimore, MD

    Early diagnosis of PV nephropathy(PyVAN) leads to overall improvements in the short term but sclerosing sequelae and risk for rejection (mainly antibody mediated) contribute to…
  • 2017 American Transplant Congress

    Renal Function Outcomes of Hypertensive Living Kidney Donors (HLD) and Recipients of HLD Kidneys: Results of a Case-Control Study.

    T. Pesavento,1 A. Diez,1 R. Pelletier,2 U. Nori,1 J. VonVisger.1

    1Nephrology, Ohio State, Columbus, OH; 2Transplant, Ohio State, Columbus, OH

    As the shortage of suitable deceased and living kidney donors (LD) persists, medically complex LD, including those with hypertension (HTN), are being considered for donation…
  • 2017 American Transplant Congress

    Influence of Tacrolimus Metabolism Rate on Patients' Survival After Renal Transplantation.

    G. Thölking, J. Steinke, K. Schuette-Nuetgen, H. Pavenstädt, B. Suwelack, S. Reuter.

    Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, Münster, Germany

    Introduction: Tacrolimus (Tac) is an integral part of the immunosuppressive regimen after renal transplantation (RTx). A fast Tac metabolism rate defined as the Tac blood…
  • 2017 American Transplant Congress

    Belatacept in Chronic Kidney Disease Stabilizes and Improves Renal Function in Pancreas Transplant Recipients: Intermediate Results.

    J. Chen, M. Mujtaba, T. Taber, M. Yaqub, J. Powelson, O. Adebiyi, J. Fridell, A. Sharfuddin.

    Indiana University Health, Indianapolis

    Background: We report our experience in converting Pancreas Transplant recipients from tacrolimus to Belatacept in order to avoid further worsening of kidney function.Results: Eight (7…
  • 2017 American Transplant Congress

    The Impact of Marginal Factors on the Postoperative Kidney Function of Complex Living Donors for Kidney Transplantation.

    T. Hiramitsu, K. Futamura, M. Okada, M. Tsujita, N. Goto, S. Narumi, Y. Watarai.

    Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan

    BackgroundMedically complex living donors with marginal factors are increasing.MethodsBetween January 2008 and May 2015, 639 living donors for kidney transplantation were included. Marginal factors for…
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