2017 American Transplant Congress
Patients with Renal Failure Have a pERK-Dependent Defective TCR-Mediated Activation of CD4+ T Cells.
Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands
Introduction Patients with end-stage renal disease (ESRD) have an impaired immune response with a prematurely aged T cell system. Mitogen-activated protein kinases (MAPKs) including extracellular…2017 American Transplant Congress
Increased T Cell Exhaustion in Dialysis Patients.
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
Infection is a major complication post-transplantation. Evaluating the immune system prior to transplant may allow better optimization of immunosuppression dose. T cell exhaustion has been…2017 American Transplant Congress
Non-Donor-Specific Anti-HLA Antibodies Have an Adverse Impact in Kidney Graft Outcomes.
1CHP, Porto, Portugal; 2IPST, Porto, Portugal
Few studies have studied the impact of non-donor-specific antibodies (NDSA) in kidney transplantation (KT), with most showing no impact of these antibodies. As antibody-mediated graft…2017 American Transplant Congress
Acute Renal Replacement Therapy in Pediatric Liver Transplantation: A Predictor of Increased Risk.
1Surgery, UCLA, Los Angeles, CA; 2Pediatric Gastroenterology, UCLA, Los Angeles, CA
BackgroundAmong pediatric patients (≤18 yrs) awaiting liver transplantation (LT), limited data exist on the prognostic significance of acute (<90d) renal replacement therapy (RRT) prior to…2017 American Transplant Congress
Improved Creatinine Immediately Post-LVAD Predicts Lower AKI Risk After Heart Transplant.
Background-Left ventricular assist device(LVAD) placement often improves renal function in patients with advanced heart failure. In those bridged to transplant with LVAD support it is…2017 American Transplant Congress
Sequential Liver-Kidney Transplantation Is Equivalent to Simultaneous Liver–Kidney Transplantation in Candidates Requiring Dialysis Pre-Transplant.
Surgery, Duke University Medical Center, Durham, NC
Introduction: Liver transplant is the optimal therapy for patients with end-stage liver disease (ESLD). Appropriately-selected candidates with renal impairment benefit from transplantation of liver and…2017 American Transplant Congress
Kidney Re-Transplant Rate in Simultaneous Kidney Pancreas Transplant Recipients.
Transplant, University of Nebraska Medical Center, Omaha, NE
Bladder drainage, although no longer the most commonly performed method for exocrine drainage of the pancreas, remains an option for patients undergoing simultaneous pancreas- kidney…2017 American Transplant Congress
Serum Phosphorus and Cardiovascular Disease Outcomes, Graft Failure, or Total Mortality in Chronic Kidney Transplant Recipients.
Mild hyperphosphatemia may be present in chronic kidney transplant recipients [KTRs]. Limited data are available from large, multicenter KTR cohorts assessing the potential relationships between…2017 American Transplant Congress
A Decade of Paediatric Kidney Transplantation in Children Weighing <20kg.
Introduction: Renal transplantation is the gold standard treatment for end-stage kidney disease. There are increased challenges in paediatric renal transplant recipients under 20kg, especially when…2017 American Transplant Congress
Does Simultaneous Liver Kidney Transplant in Patients with MELD ≥35 on Renal Replacement Therapy at the Time of Transplant Improve Outcome?
Transplant Hepatology, Univ. of Tennessee, Memphis, TN
Background: A significant proportion of patients with MELD ≥35 have renal failure requiring renal replacement therapy (RRT) at the time of transplant, and receive either…
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