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American Transplant Congress abstracts

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Articles tagged "Renal dysfunction"

  • 2020 American Transplant Congress

    Incidence of Chronic Kidney Disease after Liver Transplantation Using Measured GFR

    N. R. Mazumder1, J. Levitsky1, G. Saracino2, G. Klintmalm3, J. Trotter2, S. Asrani2

    1Gastroenterology and Hepatology, Northwestern University, Chicago, IL, 2Transplant Hepatology, Baylor University Medical Center Dallas, Dallas, TX, 3Transplant Surgery, Baylor University Medical Center Dallas, Dallas, TX

    *Purpose: Historical rates of ESRD after LT are 8% (1 year) and 18% (5 years) (Ojo NEJM 2003). However, these rates were based older estimates…
  • 2020 American Transplant Congress

    Avoiding Surveillance Biopsy: How? When? Now!

    A. Ang1, C. Schieve2, S. Rose2, C. Kew1, M. R. First2, R. B. Mannon1

    1School of Medicine, University of Alabama, Birmingham, Birmingham, AL, 2Transplant Genomics Inc., Mansfield, MA

    *Purpose: The TruGraf™ blood test measures a specific gene expression signature in the peripheral blood mononuclear cells to enable noninvasive serial assessment of kidney transplant…
  • 2020 American Transplant Congress

    Large Academic Center Experience with Treatment of Suspected/Confirmed Kidney Transplant Active Antibody Mediated Rejection

    J. T. Reece1, B. A. Steiner2, V. Bhoj1, N. Aqui1, R. D. Bloom3, J. Trofe-Clark4

    1Transfusion Medicine Div, Univ of Pennsylvania, Philadelphia, PA, 2Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, 3Renal Div, Univ of Pennsylvania, Philadelphia, PA, 4Pharmacy, Hospital of University of Pennsylvania, Philadelphia, PA

    *Purpose: Therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIG) are common active antibody mediated rejection (ABMR) treatments in kidney transplant recipients (KTRs), but with unclear…
  • 2020 American Transplant Congress

    ANG-3777, A Hepatic Growth Factor Mimetic, Attenuates Post-Transplant Renal Dysfunction in Rats

    P. Narayan, I. D. Goldberg

    Angion Biomedica, Uniondale, NY

    *Purpose: ANG-3777, a small-molecule mimetic of hepatocyte growth factor (HGF), has the potential to exert antifibrotic and nephroprotective effects. A rat model of renal transplantation…
  • 2020 American Transplant Congress

    Time-Zero Histology Correlates with Donor Characteristics but Does Not Predict Short-Term Outcomes in Kidney Transplantation

    S. Raza, G. Agarwal, D. Anderson, M. Deierhoi, H. Fatima, M. Hanaway, J. Locke, P. MacLennan, B. Orandi, C. Young, R. Mannon, M. Seifert

    University of Alabama School of Medicine, Birmingham, AL

    *Purpose: Time-zero biopsies provide important information about baseline histology but their clinical utility compared to other non-invasive predictors is unclear. Our center performs universal time-zero…
  • 2020 American Transplant Congress

    Recurrence of Igg3Lambda Restricted Cryoglobulinemic Glomerulonephritis in a Renal Allograft: Resolution after Daratumumab Treatment

    S. C. Jordan, R. Vescio, J. Hou, N. Ammerman, R. Najjar, S. Sethi, E. Huang, A. Peng, A. Vo

    Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: C3GN encompasses a group of renal diseases often associated with paraproteinemias. Recurrence in renal allografts is reported. Currently, there are no effective or curative…
  • 2020 American Transplant Congress

    Clinical Implication of Tertially Lymphoid Tissue in the Renal Graft

    M. Saito1, Y. Lee2, Y. Sato2, S. Narita1, S. Satoh1, M. Yanagita2, T. Habuchi1

    1Urology, Akita University Hospital, Akita, Japan, 2Nephrology, Kyoto University Graduate School of Medicine, Kyoto, Japan

    *Purpose: Tertialy lymphoid organs (TLTs) are defined as inducible lymphoid tissues that arise in non-lymphoid organs, and chronic sustained inflammation is one of the most…
  • 2020 American Transplant Congress

    Evaluation of Apixaban Usage in Solid Organ Transplant Patients with Renal Impairment

    L. Rakouki, R. Yau, C. Tunwar

    Pharmacy, CHI St. Luke's Health-Baylor St. Luke's Medical Center, Houston, TX

    *Purpose: There remains a gap in the literature for apixaban dosing recommendations for treatment of deep vein thrombosis (DVT) or pulmonary embolism (PE) in special…
  • 2020 American Transplant Congress

    Incidence and Outcomes of Secondary Cutaneous Malignancies among Renal Transplant Recipients

    T. Maw1, P. Vaidya1, J. Samaan2, S. Ghanshani1, G. In1

    1Keck School of Medicine, LA, CA, 2Cedar Sinai Hospital, LA, CA

    *Purpose: Solid-organ transplant recipients on immunosuppressive therapy are known to have higher morbidity and mortality from secondary malignancies; however, there are no established guidelines for…
  • 2020 American Transplant Congress

    Two Pilot Studies Exploring the Diagnostic and Predictive Potential of Serum LAG3 and FGL1 in Kidney Transplant Recipients

    Y. Li1, L. Yan1, Y. Li1, C. Yang1, Z. Wan1, Y. An1, Y. Bai1, L. Wang1, Y. Shi2

    1Department of Laboratory Medicine, West China Hospital, Chengdu, China, 2Department of Nephrology, West China Hospital, Chengdu, China

    *Purpose: Lymphocyte activation gene 3 (LAG3), an immune checkpoint, plays an important role in the negative regulation of immune response and the induction of immune…
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