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American Transplant Congress abstracts

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Articles tagged "Renal dysfunction"

  • 2015 American Transplant Congress

    A Retrospective Review of a Renal Sparing Protocol in Orthotopic Liver Transplantation

    B. Pierce,2 J. Levitsky,1,3 M. McLaughlin,2 C. Richardson.2

    1Department of Medicine, Northwestern Medicine, Chicago, IL; 2Pharmacy, Northwestern Medicine, Chicago, IL; 3Hepatology, Northwestern Medicine, Chicago, IL.

    Liver transplant recipients with pre-existing renal insufficiency are placed on a renal sparing protocol (RSP) consisting of delayed initiation of low-dose tacrolimus in addition to…
  • 2015 American Transplant Congress

    Cyclosporine Nephrotoxicity Is Associated With Diminished Expression of Heat Shock Protein 27 (HSP27) and Loss of Claudin-2-Dependent Intercellular Adhesion

    A. Zmijewska,1 R. Thuillier,2 J. Chen,1 J. Zmijewski,1 R. Mannon.1

    1Medicine, University of Alabama at Birmingham, Birmingham, AL; 2INSERM U1082, Poitiers, France.

    Although Cyclosporine A (CsA), a calcineurin inhibitor (CNI), is an effective immunosuppressant used to prevent kidney allograft rejection, prolonged administration is frequently associated with kidney…
  • 2015 American Transplant Congress

    Survival Benefit of Simultaneous Liver Kidney (SLK) Transplant in Liver Transplant Candidates With Renal Dysfunction

    B. Tanriover,1 S. Zhang,2 J. Marrero.3

    1Medicine/Nephrology, UT Southwestern, Dallas, TX; 2Clinical Sciences, UT Southwestern, Dallas, TX; 3Medicine/Hepatology, UT Southwestern, Dallas, TX.

    Survival benefit of SLK over liver transplant alone (LTA) in patients with same level of renal dysfunction and effect of organ quality on mortality are…
  • 2015 American Transplant Congress

    Norovirus Infection in Renal Transplant Recipients – Clinical Severity and Genotype Identification

    J. Roodnat,1 Y. Rakké,1 J. Beek van,3 M. Koopmans,2 M. Betjes,1 W. Weimar,1 M. Beersma.2

    1Internal Medicine, Erasmus Medical Centre, Rotterdam, Netherlands; 2Department of Viroscience, Erasmus Medical Centre, Rotterdam, Netherlands; 3National Institute for Public Health and the Environment, Bilthoven, Netherlands.

    Introduction: Norovirus (NoV) is increasingly recognized as causative agent of gastro-enteritis in renal transplant recipients.Methods: We performed a retrospective study (2003-2012) to investigate the clinical…
  • 2015 American Transplant Congress

    Intraoperative Renal Replacement Therapy During Liver and Liver-Kidney Transplant: Outcomes of 155 Cases

    M. Mai,1 E. Golan,2 K. Croome,1 A. Keaveny,1 B. Taner,1 T. Gonwa,1 H. Wadei.1

    1Transplantation, Mayo Clinic, Jacksonville, FL; 2Florida State University, Tallahassee, FL.

    Background: Renal dysfunction in liver (LT) and liver-kidney (LKT) transplant candidates increases intraoperative risks of electrolyte disturbances and volume excess complications. The role of intraoperative…
  • 2015 American Transplant Congress

    Pre-Transplant Angiotensin Receptor II Type 1 Antibodies (AT1R) and Serum Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) as Predictors of Post Transpalnt FSGS Recurrence

    A. Khalil, T. Tim, A. Sharfuddin, S. Doshi, M. Yaqub, D. Mishler, W. Goggins, M. Mujtaba.

    Indiana University school of Medicine-IU Health Transplant, Indianapolis, IN.

    Approximately 30% of renal transplant patients develop recurrence of FSGS in the first kidney allograft. AT1R is expressed on podocytes; its expression is elevated in…
  • 2015 American Transplant Congress

    Comparison of Renal Outcomes for Liver Transplant Recipients With Pretransplant Renal Dysfunction Receiving Sirolimus Or Tacrolimus With Rabbit Antithymocyte Globulin Induction

    B. Duhart,1 W. Ally,2 V. Rao,3 A. Krauss,4 J. Eason,3 J. Vanatta.3

    1University of Tennessee College of Pharmacy, Memphis, TN; 2Pharmacy, University of Virginia Medical Center, Charlottesville, VA; 3Surgery, Methodist University Hospital Transplant Institute/University of Tennessee Health Science Center, Memphis, TN; 4Pharmacy, Methodist University Hospital, Memphis, TN.

    Published data are limited describing renal outcomes in orthotopic liver transplant (OLT) recipients prescribed de novo sirolimus (SRL) maintenance immunosuppression and rabbit antithymocyte globulin (rATG).…
  • 2015 American Transplant Congress

    Targeting Leukocyte Integrin CD11b/CD18 With a Novel mAb Salvages Renal Function Following an Otherwise Irreversible Ischemic Insult in Cynomolgus Monkeys

    A. Cosimi,1 A. Dehnadi,1 R. Smith,2 D. Ko,1 X. Li,3 M. Arnaout.3

    1Transplant Surgery, Massachusetts General Hospital, Boston, MA; 2Pathology, MGH, Boston, MA; 3Nephrology, MGH, Boston, MA.

    Allograft dysfunction resulting from ischemic reperfusion injury (IRI) leads to increased peri-transplant costs, morbidity, and inferior long-term survival. Leukocyte/endothelial adhesion is an important pathway contributing…
  • 2015 American Transplant Congress

    Renal Function Difference Between Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy and HBIG Combined With Entecavir in Liver Recipients

    J. Lee,1,2 J. Lee,1,2 J. Lee,3 M. Kim,1,2 M. Ju,1,2 G. Choi,1,2 J. Choi,1,2 S. Kim,1,2 D. Joo.1,2

    1Department of Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seroul, Korea; 2Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; 3Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.

    Background: To reduce the HBV reinfection after liver transplantation, anti-hepatitis B immunoglobulin (HBIG) alone or combination with antiviral nucleotide analogues are usually used regimen. However,…
  • 2015 American Transplant Congress

    Clinicopathological Scenarios (CPS) Defined by Viremia, Creatinine and Histology in Polyomavirus Nephropathy Differ in 1st and 2nd (Follow-Up) Biopsy

    C. Drachenberg, M. Chaudhry, F. Yang, R. Ugarte, A. Haririan, M. Mavanur, C. Cangro, B. Thomas, N. Costa, E. Ramos, M. Weir, J. Papadimitriou.

    Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Studies of sequential kidney biopsies (KB) after the diagnosis of polyomavirus allograft nephropathy (PVN) are scarce and clinicopathological evolution of PVN poorly understood. In practice…
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