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Articles tagged "Renal dysfunction"

  • 2015 American Transplant Congress

    Calcineurin Inhibitors (CNI) Minimization Associated With Mammalian Target of Rapamycin Inhibitors (i-mTOR) to Improve Renal Function in Renal Grafts from Uncontrolled Donation After Cardiac Death Donors (UDCDD)

    M. Molina,1 E. Gutierrez,1 S. González-Sanchidrian,2 E. González,1 J. Cabrera,1 N. Polanco,1 A. Hernández,1 A. Sevillano,1 M. Praga,1 A. Andres.1

    1Nephrology, Hospital 12 de Octubre, Madrid, Spain; 2Nephrology, Hospital San Pedro de Alcántara, Caceres, Spain.

    INTRODUCTION: Ischemia injury in kidneys grafts from UDCDD could produce a poor renal function. Minimized blood levels of CNI associated with i-mTOR therapy could avoid…
  • 2015 American Transplant Congress

    Correlation of Serum Creatinine-Based Equations With Radionuclide GFR in Candidates for Liver Transplantation

    A. Alqallaf, A. Alam, P. Ghali, M. Cantarovich.

    McGill University Health Centre, Montreal, QC, Canada.

    Background: Renal dysfunction is common prior to liver transplantation (LTx); however, the best way to determine the glomerular filtration rate (GFR) pre-LTx is unclear. Our…
  • 2015 American Transplant Congress

    Molecular Classifiers Accurately Measure the Degree of Fibrosis in Human Kidney Transplant Biopsies

    J. Venner, J. Reeve, P. Halloran.

    University of Alberta, Edmonton, Canada.

    Irreversible injury in organ transplants is an important clinical parameter, and is estimated by histology as the observed “ci” lesion, but with considerable inter-observer variability…
  • 2015 American Transplant Congress

    Long-Term Results After Heart Transplantation – A Randomized Trial Comparing Tacrolimus Versus Cyclosporine A in Combination With Mycophenolate Mofetil After a Mean Duration of 15 Years

    S. Guethoff,1 C. Grinninger,1 B. Reichart,2 P. Ueberfuhr,1 C. Hagl,1 B. Meiser.2

    1Department of Cardiac Surgery, Ludwig-Maximilians University, Munich, Germany; 2Transplantation Center, Ludwig-Maximilians University, Munich, Germany.

    Purpose. Development of cardiac allograft vasculopathy (CAV), renal dysfunction and malignancies are the main risks due to long-term immunosuppressive therapy after heart transplantation (HTx). We…
  • 2015 American Transplant Congress

    Estimation of Glomerular Filtration Rate With Serum Cystatin C Accurately Discriminates Renal Dysfunction in Liver Transplant Candidates With End-Stage Liver Disease

    S. Gonzalez,1 J. Trotter,1 H. Szerlip,2 M. Levy,3 A. Chandrakantan,4 A. Yango,4 A. Rajagopal,4 Y. Barri,4 K. Rice,4 M. Saim,2 L. Melton,4 M. Emmett,2 G. Klintmalm,3 B. Fischbach.4

    1Hepatology, Baylor Simmons Transplant Institute, Fort Worth, TX; 2Nephrology, Baylor University Medical Center, Dallas, TX; 3Transplant Surgery, Baylor Simmons Transplant Institute, Fort Worth, TX; 4Nephrology, Baylor Simmons Transplant Institute, Fort Worth, TX.

    Background: Renal insufficiency is common in end-stage liver disease (ESLD) and is linked to survival in patients awaiting liver transplantation. Serum creatinine correlates poorly with…
  • 2015 American Transplant Congress

    A Joint Survival Longitudinal Approach to Better Assess the Etiological Role of Risk Factors of Kidney Transplant Graft Failure

    M.-C. Fournier,1,2 E. Dantan,1 Y. Foucher,1,2 M. Giral.2

    1EA 4275 - SPHERE - Biostatistique, Pharmacoépidémiologie et Mesures Subjectives en Santé, Université de Nantes, Nantes, France; 2INSERM CR1064 Centre pour la Recherche en Transplantation et Immunointervention (CRTI), Institut Transplantation-Urologie-Néphrologie (ITUN), Nantes, France.

    Background. Although risk factors of graft failure after renal transplantation have been widely considered, it is difficult to distinguish their etiological role: a direct association…
  • 2015 American Transplant Congress

    Dengue Virus Infection Among Renal Transplant Recipients: A Series of 10 Cases in a Tropical Country

    S. Costa,1,2 C. Jacinto,1 L. Martiniano,1 Y. Amaral,1 F. Paes,2 M. Sales,2 E. Daher,1,2 G. Junior,3 R. Esmeraldo.2

    1Post-Graduation Program in Medical Sciences, Department of Internal Medicine, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil; 2Division of Renal Transplantation, Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil; 3Post-Graduation Program in Collective Health, School of Medicine, Sciences Center, University of Fortaleza, Fortaleza, Ceará, Brazil.

    Background: Dengue in an important endemic disease in many parts of the world. The aim of this study is to describe a case series of…
  • 2015 American Transplant Congress

    Clinical and Radiological Predictors of Transplant Renal Artery Stenosis (TRAS)

    H. Wadei,1 D. Hodge,2 L. White,2 A. Ayub,3 N. Aslam,3 T. Gonwa,1 G. Frey,4 D. Sella,4 M. Mai.1

    1Transplant, Mayo Clinic, Jacksonville, FL; 2Biomedical Statistics, Mayo Clinic, Jacksonville, FL; 3Department of Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL; 4Diagnostic Radiology, Mayo Clinic, Jacksonville, FL.

    Elevated peak systolic velocity (PSV) on Doppler ultrasound at the transplant renal artery (TRA) does not always correlate with true transplant renal artery stenosis (TRAS)…
  • 2015 American Transplant Congress

    A Retrospective Review of a Renal Sparing Protocol in Orthotopic Liver Transplantation

    B. Pierce,2 J. Levitsky,1,3 M. McLaughlin,2 C. Richardson.2

    1Department of Medicine, Northwestern Medicine, Chicago, IL; 2Pharmacy, Northwestern Medicine, Chicago, IL; 3Hepatology, Northwestern Medicine, Chicago, IL.

    Liver transplant recipients with pre-existing renal insufficiency are placed on a renal sparing protocol (RSP) consisting of delayed initiation of low-dose tacrolimus in addition to…
  • 2015 American Transplant Congress

    Cyclosporine Nephrotoxicity Is Associated With Diminished Expression of Heat Shock Protein 27 (HSP27) and Loss of Claudin-2-Dependent Intercellular Adhesion

    A. Zmijewska,1 R. Thuillier,2 J. Chen,1 J. Zmijewski,1 R. Mannon.1

    1Medicine, University of Alabama at Birmingham, Birmingham, AL; 2INSERM U1082, Poitiers, France.

    Although Cyclosporine A (CsA), a calcineurin inhibitor (CNI), is an effective immunosuppressant used to prevent kidney allograft rejection, prolonged administration is frequently associated with kidney…
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