ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal dysfunction"

  • 2015 American Transplant Congress

    Comparison of Renal Outcomes for Liver Transplant Recipients With Pretransplant Renal Dysfunction Receiving Sirolimus Or Tacrolimus With Rabbit Antithymocyte Globulin Induction

    B. Duhart,1 W. Ally,2 V. Rao,3 A. Krauss,4 J. Eason,3 J. Vanatta.3

    1University of Tennessee College of Pharmacy, Memphis, TN; 2Pharmacy, University of Virginia Medical Center, Charlottesville, VA; 3Surgery, Methodist University Hospital Transplant Institute/University of Tennessee Health Science Center, Memphis, TN; 4Pharmacy, Methodist University Hospital, Memphis, TN.

    Published data are limited describing renal outcomes in orthotopic liver transplant (OLT) recipients prescribed de novo sirolimus (SRL) maintenance immunosuppression and rabbit antithymocyte globulin (rATG).…
  • 2015 American Transplant Congress

    Targeting Leukocyte Integrin CD11b/CD18 With a Novel mAb Salvages Renal Function Following an Otherwise Irreversible Ischemic Insult in Cynomolgus Monkeys

    A. Cosimi,1 A. Dehnadi,1 R. Smith,2 D. Ko,1 X. Li,3 M. Arnaout.3

    1Transplant Surgery, Massachusetts General Hospital, Boston, MA; 2Pathology, MGH, Boston, MA; 3Nephrology, MGH, Boston, MA.

    Allograft dysfunction resulting from ischemic reperfusion injury (IRI) leads to increased peri-transplant costs, morbidity, and inferior long-term survival. Leukocyte/endothelial adhesion is an important pathway contributing…
  • 2015 American Transplant Congress

    Renal Function Difference Between Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy and HBIG Combined With Entecavir in Liver Recipients

    J. Lee,1,2 J. Lee,1,2 J. Lee,3 M. Kim,1,2 M. Ju,1,2 G. Choi,1,2 J. Choi,1,2 S. Kim,1,2 D. Joo.1,2

    1Department of Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seroul, Korea; 2Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; 3Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.

    Background: To reduce the HBV reinfection after liver transplantation, anti-hepatitis B immunoglobulin (HBIG) alone or combination with antiviral nucleotide analogues are usually used regimen. However,…
  • 2015 American Transplant Congress

    Clinicopathological Scenarios (CPS) Defined by Viremia, Creatinine and Histology in Polyomavirus Nephropathy Differ in 1st and 2nd (Follow-Up) Biopsy

    C. Drachenberg, M. Chaudhry, F. Yang, R. Ugarte, A. Haririan, M. Mavanur, C. Cangro, B. Thomas, N. Costa, E. Ramos, M. Weir, J. Papadimitriou.

    Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Studies of sequential kidney biopsies (KB) after the diagnosis of polyomavirus allograft nephropathy (PVN) are scarce and clinicopathological evolution of PVN poorly understood. In practice…
  • 2015 American Transplant Congress

    Correlates and Consequences of Gout Among Living Kidney Donors

    N. Lam,1 A. Garg,1 D. Segev,2 M. Schnitzler,3 H. Xiao,3 D. Axelrod,4 J. Tuttle-Newhall,3 D. Brennan,5 B. Kasiske,6 K. Lentine.3

    1Western Uni., London, Canada; 2John Hopkins Uni., Baltimore; 3Saint Louis Uni., St. Louis; 4Dartmouth Hitchcock Medical Center, Hanover; 5Washington Uni., St. Louis; 6Uni. of Minnesota, Minneapolis.

    Background: Currently, the demographic correlates and consequences of gout in living kidney donors are understudied.Methods: We examined a novel database that linked national U.S. identifiers…
  • 2015 American Transplant Congress

    Isolated Microcirculation Inflammation Negatively Impacts Renal Graft Function at 5 Years

    A. Chapelet,1 M. Touzot,1 M. Fournier,2 A. Cesbron,3 K. Renaudin,4 A. Moreau,4 E. Morelon,5 D. Anglicheau,6 M. Giral.1

    1Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; 2EA 4275 SPHERE—Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences, University of Nantes, Nantes, France; 3Etablissement Français du Sang (EFS), Nantes, France; 4Service d'Anatomie et Cytologie Pathologiques, CHU Nantes, Nantes, France; 5Service de Néphrologie, Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, Lyon, France; 6Service de Transplantation Rénale et de Soins Intensifs, Hôpital Necker, Paris, France.

    BACKGROUND: Microcirculation inflammation (MI, ie: glomerulitis (g) and peritubular capillaritis (ptc)) associated with anti-HLA Donor Specific Antibody (DSA) with or without C4d deposits in ptc…
  • 2015 American Transplant Congress

    Lung Transplant Patients With Elevated Baseline Pulmonary Arterial Pressures Are More Likely to Recover from Post-Transplant Acute Kidney Injury

    B. Stephany,1 E. Wehbe,2 M. Budev.3

    1Nephrology & Hypertension, Cleveland Clinic, Cleveland, OH; 2Nephrology, Wichita, KS; 3Pulmonary, Allergy & Critical Care, Cleveland Clinic, Cleveland, OH.

    Purpose: Elevated pre-operative pulmonary arterial pressures predict acute kidney injury (AKI) after lung transplant. It is unknown if the elevated pulmonary pressures predict recovery from…
  • 2015 American Transplant Congress

    Renal Function Following Basiliximab Induction in Liver Transplant Recipients

    J. Hagopian, T. Horwedel, L. Bowman, K. Collins, M. Doyle.

    Washington University School of Medicine, St. Louis.

    Purpose: Reports of the use of antibody induction to delay the start of calcineurin inhibitor therapy postoperatively in patients with renal insufficiency at the time…
  • 2015 American Transplant Congress

    Acute Kidney Injury After Lung Transplantation – Incidence, Risk Factors and Mechanisms

    F. Gueler,1 G. Warnecke,5 M. Peperhove,2 M.-S. Jang,1 C. Schroeder,3 S. Tewes,2 B. Wiese,6 C. Fegbeutel,5 R. Lichtinghagen,7 B. Jüttner,8 F. Wacker,2 D. Hartung,2 B. Akerstrom,4 M. Gram,4 H. Haller,1 A. Haverich,9 K. Hueper.2

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Radiology, Hannover Medical School, Hannover, Germany; 3Proteomics, German Research Cancer Center, Heidelberg, Germany; 4Physiology, Lund University, Lund, Sweden; 5Thoracic and Cardiac Surgery, Hannover Medical School, Hannover, Germany; 6Medical Statistics, Hannover Medical School, Hannover, Germany; 7Laboratory Medicine, Hannover Medical School, Hannover, Germany; 8Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany; 9Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany.

    Background: Acute kidney injury (AKI) is a frequent and severe complication after solid organ transplantation. In a retrospective analysis and afterwards in a prospective clinical…
  • 2015 American Transplant Congress

    Everolimus With Low Dose Tacrolimus in Intestinal Transplantation

    T. Beduschi, J. Garcia, J. Lugo-Baruqui, J. Fan, S. Nishida, J. Jebrock, A. Tekin, G. Selvaggi, P. Ruiz, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Introduction: Renal dysfunction is a well-known complication after organ transplant given immunosuppression (ISP) with calcineurin inhibitors. This is especially true after intestinal transplant (ITx) given…
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