ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Rejection"

  • 2019 American Transplant Congress

    Continuous 24-Hour vs. Daily Antithymocyte Globulin (ATG) Infusions for Treatment of Renal Allograft Rejection: Preliminary Results of a Prospective Trial

    S. J. Patel, S. Kuten, R. Knight, J. Nolte-Fong, D. Nguyen, E. Graviss, A. Gaber

    Methodist Hospital, Houston, TX

    *Purpose: When used for acute rejection (AR), ATG is generally administered in the inpatient setting, given the need for intravenous (IV) access, risk of infusion-related…
  • 2019 American Transplant Congress

    Impact Of Inhaled Vasodilator Therapy On Early Morbidity And Mortality After Lung Transplant

    M. Tomeczkowicz1, A. Wexler1, M. Patel2, J. Fernandez-Castillo2, J. Rusniak1, E. Mancl3, S. Quddus2

    1Department of Pharmacy, Loyola University Medical Center, Maywood, IL, 2Division of Pulmonary and Critical Care, Loyola University Medical Center, Maywood, IL, 3Loyola University Medical Center, Maywood, IL

    *Purpose: Within the first 72 hours of lung transplant, recipients may develop primary graft dysfunction (PGD). This complication is associated with acute and chronic rejection,…
  • 2019 American Transplant Congress

    Adjunctive Therapy With Tocilizumab For Treatment Of Acute Antibody Mediated Rejection – 2 Year Experience

    K. Venkatachalam, R. Delos Santos, B. Heady, A. Malone, T. Alhamad

    Washington University, St. Louis, MO

    *Purpose: Reporting our center's experience in use of tocilizumab for treatment of antibody mediated rejection*Methods: We have previously reported the efficacy of Tocilizumab (TCZ), an…
  • 2019 American Transplant Congress

    Biomarkers in Multivisceral and Intestinal Transplantation

    D. A. Cheung1, J. Garcia1, T. Beduschi2, A. H. Langshaw1, K. L. Arheart3, I. A. Gonzalez4

    1Pediatric Gastroenterology, University of Miami, Miami, FL, 2Surgery, Division of Liver/GI Transplant, University of Miami, Miami, FL, 3Public Health Sciences, Division of Biostatistics, University of Miami, Miami, FL, 4Pediatric Infectious Diseases and Immunology, University of Miami, Miami, FL

    *Purpose: Multivisceral transplant (MVT) and isolated intestinal transplant (ITx) are complex surgical procedures that result in a pro-inflammatory state, making interpretation of biomarkers in the…
  • 2018 American Transplant Congress

    Comparison of Induction and Maintenance Immunosuppression Regimens in Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Registry

    S. Nagai,1 M. Rizzari,1 Y. Muszkat,2 K. Collins,1 A. Yoshida,1 S-.M. Jafri,2 M. Abouljoud.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI.

    Aim: Induction and maintenance immunosuppression regimens in intestinal transplant widely vary among centers. The aim of this study was to investigate an association between immunosuppression…
  • 2018 American Transplant Congress

    Incidence of Acute Cellular Rejection in Liver Transplant Patients Receiving Direct Acting Antivirals for Hepatitis C Treatment

    D. Bley,1 L. Sagardia,1 R. Ford,2 S. Todd.1

    1Pharmacy, Emory University Hospital, Atlanta, GA; 2School of Medicine, Emory University, Atlanta, GA.

    Direct acting antivirals (DAAs) have been used for the treatment of hepatitis C (HCV) in liver transplant patients since early on after their approval, however…
  • 2018 American Transplant Congress

    Pro-Inflammatory B Cells Predict Progressive Minimal Early Renal Allograft Inflammation Which is Associated with Poor Graft Outcomes

    A. Sharma, A. Cherukuri, D. Chittka, R. Mehta, S. Hariharan, D. Rothstein.

    UPMC, Pittsburgh.

    The clinical significance of minimal tubulointerstitial inflammation (MTI:'t'+'i'scores 0.5-1.5) and Banff Borderline changes (BBC:'t'+'i'scores 2-3) in early renal allograft biopsies is unclear. The rate and…
  • 2018 American Transplant Congress

    DSA with TCMR Identifies High Risk Renal Transplant Recipients That Can Be Predicted by Proinflammatory Transitional B Cells

    D. Chittka, A. Cherukuri, A. Sharma, R. Mehta, S. Hariharan, D. Rothstein.

    Starzl Transplant Inst., Univ. of Pittsburgh, Pittsburgh.

    Post-transplant DSA is strongly associated with poor graft outcomes but has limited predictive value. In this prospective study we aimed to risk-stratify patients with early…
  • 2018 American Transplant Congress

    Isolation and Profiling of miRNAs from Formalin Fixed Paraffin Embedded Endomyocardial Tissues from Human Heart Transplant Recipients

    R. Nog,1,2 C. Gupta,1,2 J. Fallon,1,2 J. Panza,1,2 N. Haque.2

    1Westchester Medical Center, Valhalla, NY; 2New York Medical College, Valhalla, NY.

    Allograft rejection is a common complication post heart transplant (HTx) and can be confirmed by endomyocardial biopsy (EBx) only. There is however an increasing need…
  • 2018 American Transplant Congress

    Comparison of Bortezomib in Addition to Rituximab Based Treatment of Acute Antibody Mediated Rejection in Kidney Transplantation

    A. Mattiazzi,1,2 J. Pagan,1,2 A. Arunachalam,1 I. De la Cruz Alcantara,1 J. Revollo,2 A. Centeno,2 A. Valdes,1,2 G. Guerra.1,2

    1Nephrology & Hypertension, University of Miami, Miami, FL; 2Miami Transplant Institute, Jackson Memorial Hospital, Miami, FL.

    Purpose:The optimal treatment strategy of acute antibody mediated rejection (AMR) in renal allograft recipients remains undefined. The aim of our study was to compare the…
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