2019 American Transplant Congress
Interruption of Notch Signaling via Blockade of Delta-Like Ligands 1 and 4 Prevents Co-Stimulation Blockade Resistant Allograft Rejection
Surgery and Transplantation, Emory University, Atlanta, GA
*Purpose: Co-stimulation blockade (CoB) has emerged as a promising immunosuppression strategy with the advent of belatacept, a novel CTLA4-Ig fusion protein that blocks CD28-mediated T…2019 American Transplant Congress
High Fibre Diet Prevents Transplant-Associated Dysbiosis and Prevents Kidney Allograft Rejection
*Purpose: To investigate the impact of high fibre (HF) diet or dietary supplementation with the short chain fatty acid (SCFA) sodium acetate (SA) on kidney…2019 American Transplant Congress
Clinical Implications of Serum Mac-2 Binding Protein in Regular Follow Up after Pediatric Living Donor Liver Transplantation
*Purpose: Pediatric living donor liver transplant (LDLT) patients sometimes develops graft fibrosis. They showed graft fibrosis even if their liver function tests were within normal…2019 American Transplant Congress
Analysis of Immune Cell Proportions in Kidney Transplant Biopsies of Acute Cellular Rejection and Antibody Mediated Rejection Compared with Non-Rejecters
*Purpose: Understanding the immune cell types that are associated with acute rejection (AR) in kidney transplant biopsies may lead to new therapeutic targets for AR.…2019 American Transplant Congress
Comparison with Solid Organ Transplants Reveals Distinct Face Transplant Rejection Gene Signature That Reflects the Unique Immunobiology of Skin
Brigham and Women's Hospital, Boston, MA
*Purpose: Skin containing transplants, such as face transplants, are immunologically unique. We compared the gene expression profiles of acute cellular rejection in human face transplants…2019 American Transplant Congress
Urinary Biomarkers- CXCL9 and CXCL10 for Non-Invasive, Early Diagnosis of Rejection in Pediatric Renal Transplantation
*Purpose: Renal transplantation is the treatment of choice for End Stage Renal Disease, but requires strict medication adherence and lifelong surveillance for rejection, infection and…2019 American Transplant Congress
The Effect Of Tacrolimus Trough Variability On Kidney Transplant Outcomes
*Purpose: High variability in tacrolimus as assessed by tacrolimus coefficient of variability (TCV) in trough levels of kidney transplant recipients (KTRs) has been associated with…2019 American Transplant Congress
Torque Teno Virus is a Prognostic Biomarker for Acute Biopsy-Proven Alloreactivity in Kidney Transplants
*Purpose: Drug-induced immunosuppression in kidney transplantation is crucial to prevent allograft rejection, but increases risk for infectious, cardiovascular and malignant disease. Tailoring of immunosuppressive drug…2019 American Transplant Congress
Detection and Desensitization of Donor-Specific Antibody Reduces Risk of Early but Not Late Renal Transplant Failure in a Cohort of 1000 Cases
Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan
*Purpose: The Human Organ Transplant Act in Taiwan was promulgated in 1987 and, thereafter, organ transplantation from brain-dead donors legalized. To review the results of…2019 American Transplant Congress
The Molecular Pathology of Immune Checkpoint Inhibitor-Associated Renal Allograft Rejection: Overlap with Acute Interstitial Nephritis
*Purpose: The use of immune checkpoint inhibitors (ICIs) for various malignancies has been associated with numerous immunological adverse events, including acute interstitial nephritis (AIN) in…
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