2019 American Transplant Congress
5-Year Post-Transplant Outcomes with Bortezomib-Based Desensitization in Renal Transplant Recipients
1U of Cincinnati, Cincinnati, OH, 2Christ Hospital, Cincinnati, OH
*Purpose: Renal transplant (RT) after desensitization (DS) has been associated with increased rejection rates. Proteasome inhibitor(PI)-based DS yields significant reductions in HLA Ab among sensitized…2019 American Transplant Congress
Impact of Transplant Ureteral Stricture Location and Type of Ureteral Revision on Long-Term Graft Survival and Patient Outcomes in Kidney Transplantation
*Purpose: Transplant ureteral strictures are a major cause of morbidity following kidney transplantation and often require surgical revision including ureteroureterostomy (UU) and neocystoureterostomy (NC). Our…2019 American Transplant Congress
Early And Late Borderline Lesions Exhibit Differential Outcomes In Renal Transplant Recipients
1University of Cincinnati, Cincinnati, OH, 2The Christ Hospital, Cincinnati, OH
*Purpose: A major distinguishing factor in the risk of acute rejection episodes that markedly affects graft survival is the timing of the rejection episode. Early…2019 American Transplant Congress
Comparison of Basiliximab and Alemtuzumab for Lung Transplant Induction
*Purpose: Compare alemtuzumab and basiliximab used for lung transplant in terms of rejection, CLAD, and mortality.*Methods: A retrospective review of lung transplants performed between 2010…2019 American Transplant Congress
Peritubular Capillary C4d Positivity in Renal Allograft Biopsies: Implications for Allograft Survival
Transplant Surgery, University of Cincinnati, Cincinnati, OH
*Purpose: C4d deposition in the peritubular capillaries (PTCs) is associated with acute antibody mediated rejection (AMR) and reduced renal allograft survival. PTC C4d positivity, however,…2019 American Transplant Congress
Perioperative Blood Transfusion Significantly Increases Inpatient Morbidity and Mortality in Renal Transplant Recipients: 15-year Experience
*Purpose: This study evaluates the immediate effects of perioperative blood transfusion (PBT) on inpatient morbidity and mortality among renal transplant (RT) recipients during their index…2019 American Transplant Congress
Molecular Analysis of Rejection and Injury in Human Liver Transplant Biopsies: First Results of the INTERLIVER Study
University of Alberta, Edmonton AB, AB, Canada
*Purpose: The relationship of histologic liver transplant biopsy assessments to actual rejection and injury is unclear. Recent progress in molecular reclassification of kidney, heart, and…2019 American Transplant Congress
Targeted Proteomic Analysis Detects Acute T Cell-Mediated Kidney Allograft Rejection in Belatacept-Treated Patients
Erasmus MC, Rotterdam, Netherlands
*Purpose: There is an unmet need for reliable minimally-invasive diagnostic biomarkers for immunological allograft monitoring and detection of acute kidney transplant rejection. Here, targeted proteomic…2019 American Transplant Congress
Characterizing the Dominant Phenotype in Kidney Transplant Biopsies: Improving the Prediction of Risk by a Global View of Rejection, Injury, and Atrophy-Fibrosis
*Purpose: Interpreting kidney transplant biopsies by histology or molecules involves assigning scores for separate pathologic categories: rejection, acute injury (molecules only), and chronic parenchymal loss…2019 American Transplant Congress
Rejection Of Optic And Sciatic Transplants
*Purpose: Mechanisms of rejection of peripheral nerve and optic nerve remains largely unknown. The inability to prevent rejection of the optic nerve has thwarted the…
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