ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Rejection"

  • 2020 American Transplant Congress

    Yield and Utility of Surveillance Kidney Biopsies in Pediatric Kidney Transplant Recipients at Various Time Points Post-Transplant

    A. Landsberg1, M. Riazy2, T. Blydt-Hansen1

    1Nephrology, BC Children's Hospital, Vancouver, BC, Canada, 2Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, BC, Canada

    *Purpose: There lacks consensus regarding the appropriate timing of routine surveillance biopsies (SB) for pediatric kidney transplant recipients. We evaluated the yield of positive biopsy…
  • 2020 American Transplant Congress

    A Comprehensive Evaluation of Risk Factors for Pneumocystis Jiroveci Pneumonia in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis

    N. Permpalung1, V. Kittipibul2, P. Mekraksakit3, P. Rattanawong4, S. Nematollahi1, S. Mehta-Steinke1

    1Johns Hopkins University School of Medicine, Baltimore, MD, 2University of Miami/Jackson Memorial Hospital, Miami, FL, 3Texas Tech University Health Sciences, Lubbock, TX, 4Mayo Clinic, Phoenix, AZ

    *Purpose: Pneumocytis jiroveci pneumonia (PJP) is an important opportunistic fungal infection in solid organ transplant (SOT) recipients that carries a significant morbidity and mortality. Several…
  • 2020 American Transplant Congress

    Assessment of the Usefulness of Urine Signature to Differentiate Acute Rejection in a Prospective Kidney Transplantation Cohort

    J. Seo1, S. Jung2, J. Moon2, K. Jeong3, C. Kim4, B. Chung5, J. Park6, Y. Kim7, S. Lee2

    1Department of Core Research Laboratory, Medical Science Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, 2Department of Internal Medicine, Division of Nephrology, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, 3Department of Internal Medicine, Division of Nephrology, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, 4Department of Internal Medicine, Division of Nephrology, Kyung-pook National University School of Medicine, Daegu, Korea, Republic of, 5Department of Internal Medicine, Division of Nephrology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, 6Department of Internal Medicine, Sungkyunkwan University, Samsung Hospital, College of Medicine, Seoul, Korea, Republic of, 7Department of Internal Medicine, Division of Nephrology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea, Republic of

    *Purpose: Despite many biomarker studies in the field of transplantation, development and validation of noninvasive molecular assays to diagnose disease and monitor immune activity is…
  • 2020 American Transplant Congress

    Efficacy and Possible Risk of De Novo Use of Everolimus for Primary Kidney Transplantation

    S. Narumi1, Y. Watarai1, N. Goto2, T. Hiramtsu1, M. Okada1, K. Futamura2, T. Tomosugi1, A. Kanda2, T. Kobayashi3

    1Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya City, Aichi Prefecture, Japan, 2Transplant Nephrology, Nagoya Daini Red Cross Hospital, Nagoya City, Aichi Prefecture, Japan, 3Transplant Surgery, Aichi Medical University School of Medicine, Nagakute City, Aichi Prefecture, Japan

    *Purpose: Transplant outcome and protocol stay rate of everolimus were investigated to clarify efficacy and risk of everolimus based regimens at a single institute.*Methods: During…
  • 2020 American Transplant Congress

    Clinical Performance of a Donor-Derived Cell-Free DNA Assay for Detection of Rejection in Kidney Transplant Recipients

    S. Kleiboeker, J. Grantham, K. Mickey, S. Cowden, E. Bixler, R. Sinha, M. Altrich

    Viracor Eurofins, Lees Summit, MO

    *Purpose: Rejection is a major complication in solid organ transplant recipients and diagnosis often depends on periodic invasive biopsies. Thus there is a need for…
  • 2020 American Transplant Congress

    Outcomes of Early versus Late Rejection in Kidney Transplant Recipients

    A. Jaffer, S. Chong, S. Rai, M. Harber, R. Motallebzadeh

    Centre for Transplantation, Department of Renal Medicine, University College London & Royal Free London NHS Foundation Trust, London, United Kingdom

    *Purpose: Advances in immunosuppression have resulted in significantly improved acute rejection rates and short-term renal graft survival. Several studies have suggested that late rejection (LR)…
  • 2020 American Transplant Congress

    Pancreas Transplant in Patients Older Than 50: An Analysis of Outcomes and Immunosuppression

    I. Booth1, J. Casale1, S. Freedman1, B. Ravichandran1, J. Scalea2, A. Haririan2, B. Masters1

    1Pharmacy, University of Maryland Medical Center, Baltimore, MD, 2Medicine, University of Maryland Medical Center, Baltimore, MD

    *Purpose: Pancreas transplant (PT) is the ideal therapy for many patients with diabetes and kidney failure. There are limited published data addressing the impact of…
  • 2020 American Transplant Congress

    Crosstalk between TLR4 and HLA Class I Mediates P-Selectin Expression and Monocyte Capture to Endothelial Cells

    Y. Jin, N. M. Valenzuela, R. A. Sosa, E. F. Reed

    Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA

    *Purpose: Transplant recipients developing donor specific HLA antibodies (DSA) are at risk for acute and chronic antibody-mediated rejection (AMR). DSA contribute to the process of…
  • 2020 American Transplant Congress

    Peripheral Blood RNA Sequencing Unravels a Differential Role of Coding and Non-Coding Genes by Types of Kidney Allograft Rejection

    S. Sur1, S. Pineda1, T. Sigdel1, M. Sirota1, O. Bestard2, M. Sarwal1

    1University of California San Francisco, San Francisco, CA, 2Laboratory of Experimental Nephrology and Transplantation, Barcelona, Spain

    *Purpose: Peripheral blood molecular patterns characterizing the different effector immune pathways driving kidney allograft rejection remain to be fully completely elucidated, to more fully type…
  • 2020 American Transplant Congress

    Steroid Withdrawal and Lymphocyte Subsets in Graft Capillary Blood versus Peripheral Blood in Low Immunological Risk Kidney Transplant Patients: Randomized, Parallel Group, Controlled Clinical Trial

    T. Vazquez Sanchez, A. Caballero, J. Alonso-Titos, V. Lopez, E. Sola, M. Cabello, E. Gutierrez Vilchez, M. Martínez-Esteban, P. Ruiz Esteban, J. Delgado, D. Hernandez

    Regional University Hospital, Malaga, Spain

    *Purpose: Whether steroid withdrawal can modulate the subclinical inflammatory response after a kidney transplant is unknown.*Methods: We undertook a controlled multicenter clinical trial involving 105…
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