2020 American Transplant Congress
Chronic Active T-Cell Mediated Rejection is Variably Responsive to Immunosuppressive Therapy
*Purpose: Chronic active T cell-mediated rejection (CACMR) is a newly described variant of kidney allograft rejection associated with long-term graft loss. A key histologic feature…2020 American Transplant Congress
The Use of Allosure Donor Derived Cell-Free DNA in a Community Based Kidney Transplant Program
Kidney Transplantation, Christiana Care Hospital, Newark, DE
*Purpose: Donor derived cell-free DNA (dd-cfDNA) has emerged as a marker of kidney allograft injury. Beginning in 2019, the dd-cfDNA monitoring has been introduced as…2020 American Transplant Congress
Parathyroidectomy Post Kidney Transplant: A Single Center Report of Short Term Outcomes
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Whether parathyroidectomy in ESRD patients should be performed before or after kidney transplant remains controversial. There is concern that post-transplant parathyroidectomy can adversely affect…2020 American Transplant Congress
Gene Expression Signatures Associated with Antibody-Mediated Rejection (ABMR) in Renal Allograft Biopsies (Bx) Are Beneficial to Clarifying ABMR Activity in Ambivalent Cases
*Purpose: “Thoroughly validated gene transcripts” in renal Bx was adopted as one of the criteria for ABMR diagnosis in the latest Banff classification. Here, we…2020 American Transplant Congress
Change In i-IFTA Associated with Treatment of Rejection
*Purpose: Recent studies have shown that inflammation in areas of interstitial fibrosis and tubular atrophy (i-IFTA) is associated with worse kidney allograft outcomes. How i-IFTA…2020 American Transplant Congress
Novel Role of Qa-1, a Murine Homolog of HLA-E, in Controlling Follicular Helper T Cells During Humoral Alloimmunity
*Purpose: Antibody-mediated rejection (AMR) is a major challenge in prolonging allograft survival. Limited insight into the humoral alloimmunity hinders the development of therapeutic strategies. We…2020 American Transplant Congress
The Use of Cell-Free MicroRNAs for the Diagnosis of Allograft Rejection in Liver Transplant Recipients Using Standard and Novel Direct Detection Platforms
*Purpose: Standard immunosuppression therapy (IST) in liver transplant (LTx) recipients requires a delicate balance to prevent side effects and allograft rejection (AR). There is no…2020 American Transplant Congress
Improved Platelet Sequestration with Humanization of Von Willebrand Factor in Pig Xenogeneic Lung Perfusion Model
*Purpose: Von Willebrand factor (vWF) is an important element of hemostasis and when activated, mediates platelet adhesion and promotes platelet aggregation under shear stress conditions.…2020 American Transplant Congress
FcγRIIIb Inhibits Renal Transplant Rejection by Inducing Neutrophils Apoptosis
Kidney Disease Center, The First Affiliated Hospital of Zhejiang University, Hangzhou, China
*Purpose: Fcγ receptors (FcγR) have been proposed to be involved in the pathogenesis of acute rejection (AR) after organ transplantation. However, the mechanisms by which…2020 American Transplant Congress
Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients is Associated with Increased Risk of Urinary Tract Infections and Pneumonia
University of Wisconsin, Madison, WI
*Purpose: Infections are a common cause of morbidity and mortality after kidney transplantation. Chronic active antibody mediated rejection (cABMR) is a leading cause of kidney…
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