2020 American Transplant Congress
Clinical Performance of a Donor-Derived Cell-Free DNA Assay for Detection of Rejection in Kidney Transplant Recipients
Viracor Eurofins, Lees Summit, MO
*Purpose: Rejection is a major complication in solid organ transplant recipients and diagnosis often depends on periodic invasive biopsies. Thus there is a need for…2020 American Transplant Congress
Outcomes of Early versus Late Rejection in Kidney Transplant Recipients
*Purpose: Advances in immunosuppression have resulted in significantly improved acute rejection rates and short-term renal graft survival. Several studies have suggested that late rejection (LR)…2020 American Transplant Congress
Pancreas Transplant in Patients Older Than 50: An Analysis of Outcomes and Immunosuppression
*Purpose: Pancreas transplant (PT) is the ideal therapy for many patients with diabetes and kidney failure. There are limited published data addressing the impact of…2020 American Transplant Congress
Crosstalk between TLR4 and HLA Class I Mediates P-Selectin Expression and Monocyte Capture to Endothelial Cells
Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles, CA
*Purpose: Transplant recipients developing donor specific HLA antibodies (DSA) are at risk for acute and chronic antibody-mediated rejection (AMR). DSA contribute to the process of…2020 American Transplant Congress
Peripheral Blood RNA Sequencing Unravels a Differential Role of Coding and Non-Coding Genes by Types of Kidney Allograft Rejection
*Purpose: Peripheral blood molecular patterns characterizing the different effector immune pathways driving kidney allograft rejection remain to be fully completely elucidated, to more fully type…2020 American Transplant Congress
Steroid Withdrawal and Lymphocyte Subsets in Graft Capillary Blood versus Peripheral Blood in Low Immunological Risk Kidney Transplant Patients: Randomized, Parallel Group, Controlled Clinical Trial
Regional University Hospital, Malaga, Spain
*Purpose: Whether steroid withdrawal can modulate the subclinical inflammatory response after a kidney transplant is unknown.*Methods: We undertook a controlled multicenter clinical trial involving 105…2020 American Transplant Congress
Analyzing Causes for Death-Censored Graft Failure
Charité Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Since it has been proposed that several causes could contribute to graft loss (GL), we analyzed graft failure in our center and attributed a…2020 American Transplant Congress
The Role of the Molecular Microscope to Guide Therapy for T-Cell Mediated Rejection in Kidney Transplants
1Virginia Commonwealth University, Glen Allen, VA, 2ATAGC, Edmonton, AB, Canada
*Purpose: Histologic lesions (I+T) to characterize T-cell mediated rejection (TCMR) can be non-specific. In some cases the inflammation may represent a ‘response to wounding’ rather…2020 American Transplant Congress
Incidence of Antibody Mediated Rejection in Living Kidney Transplant Recipients with Sensitizing History
*Purpose: A donor-reactive alloimmune memory response can arise from prior exposure to foreign human leukocyte antigen by sensitization history in transplant recipients. Assessing risk levels…2020 American Transplant Congress
Hepatocellular Carcinoma Recurrence after Severe Acute Cellular Rejection
1Columbia University Irving Medical Center, New York, NY, 2Weill Cornell Medicine, New York, NY
*Purpose: The interplay between acute cellular rejection (ACR), immunosuppression and hepatocellular carcinoma (HCC) recurrence in patients who underwent liver transplantation (LT) for HCC is still…
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