ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Rejection"

  • 2022 American Transplant Congress

    Development and Validation of an Integrative DD-CFDNA System to Predict Allograft Rejection: A Population Based Study

    O. Aubert, R. Brousse, J. Gueguen, M. Racape, C. Lefaucheur, A. Loupy

    Paris Translational Center for Organ Transplantation, Paris, France

    *Purpose: Post-transplantation patient care requires development and validation of non-invasive biomarkers to improve allograft monitoring and prevention from unnecessary and costly biopsies. Reports have suggested…
  • 2022 American Transplant Congress

    Racial Differences in the Predictability of Donor-Derived Cell-Free DNA Among Renal Transplant Recipients

    M. D. Williams1, N. Nimmagadda1, S. Patel2, O. Olaitan1

    1Rush University Medical Center, Chicago, IL, 2CareDx, Brisbane, CA

    *Purpose: Donor-Derived Cell-Free DNA (dd-cfDNA) is used to monitor for allograft rejection following renal transplantation. Baseline dd-cfDNA is higher in African American (AA) patients compared…
  • 2022 American Transplant Congress

    Steroid-Free Living Donor Liver Transplantation Using Rabbit Antithymocyte Globulin Induction Reduces Incidence of Acute Cellular Rejection

    C. Eymard1, S. Naik1, J. Eason2

    1James D Eason Transplant Institute, Memphis, TN, 2University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: The efficacy of steroid-free immunosuppression protocols using rabbit antithymocyte globulin (RATG) induction with tacrolimus minimization has previously been described in deceased donor liver transplantation.…
  • 2022 American Transplant Congress

    Peripheral Blood Immune Cell Profiles of Corneal Transplant with and without Acute Rejection

    J. Hjortdal1, M. Griffin2, C. C. Murphy3, S. Brouard4, N. Degauque4

    1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark, 2National University of Ireland, Galway, Galway, Ireland, 3Royal Victoria Eye and Ear Hospital, Dublin, Ireland, 4Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France

    *Purpose: Acute rejection (AR) of allogeneic corneal transplantation (CT) has a profound effect on subsequent graft survival, indicating that immunological damage is often not fully…
  • 2022 American Transplant Congress

    A Three-gene Peripheral Blood Potential Diagnosis Signature Associated With Autophagy For Antibody-mediated Rejection In Renal Transplantation

    Y. Wang, Y. Xu, H. Zhang, X. Hu

    Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

    *Purpose: Antibody-mediated rejection (AMR) is emerging as a major cause of graft loss in renal transplantation. Nowadays, non-invasive diagnosis of AMR with high accuracy is…
  • 2022 American Transplant Congress

    Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study

    N. Sulejmani1, D. Axelrod2, S. Dholakia1, S. Shah3

    1CareDx, South San Francisco, CA, 2University of Iowa, Iowa City, IA, 3University of Cincinnati, Cincinnati, OH

    *Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…
  • 2022 American Transplant Congress

    Safety and Efficacy of a Probiotic Protocol to Reduce Perioperative Infection After Liver Transplantation

    M. Jorgenson, Q. Yang, G. Leverson, C. Saddler, J. Smith, N. Safdar, D. Al-Adra

    University of Wisconsin Health, Madison, WI

    *Purpose: Evaluate efficacy and safety of a probiotic preparation to reduce perioperative infection in patients undergoing liver transplant surgery*Methods: Adult patients receiving liver transplantation from…
  • 2022 American Transplant Congress

    Transjugular Intrahepatic Portosystemic Shunt Placement is Associated with Increased All-Cause and Cardiac Mortality in Those Undergoing Liver Transplant for Nonalcoholic Steatohepatitis

    D. U. Lee1, J. Han2, J. Kwon2, K. Chang2, G. Fan2, K. Lee1, N. Urrunaga3, C. Bhati1, D. Maluf3, K. Shetty3

    1Department of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, 2Tufts Medical Center, Boston, MA, 3University of Maryland, Baltimore, MD

    *Purpose: Since the effect of transjugular intrahepatic portosystemic shunt (TIPS) on post LT outcomes is not well understood, we undertook this analysis of a large…
  • 2022 American Transplant Congress

    Antibody-Mediated Rejections with C1q-binding and without C1-Binding Donor-Specific Antibodies in Kidney Transplantation

    J. Jeon, C. Baek

    Asan Medical Center, Seoul, Korea, Republic of

    *Purpose: All donor-specific antibodies (DSAs) are not clinically relevant. Therefore, the C1q assay has been recently used, but its clinical meaning and usefulness should be…
  • 2022 American Transplant Congress

    Correlating Histology, Immunohistochemical, & Serologic Data in Heart Transplant Recipients: Implications for Molecular Diagnostic Assays

    P. Randhawa, Y. Huang

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The ISHLT classification of rejection in heart allograft biopsies is independent of DSA status. There is only limited data on the prevalence of DSA…
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