2015 American Transplant Congress
HLA Broad Antigen and Eplet Mismatches in Determining the Risk of Acute Rejection After Kidney Transplantation
Aim: To determine the clinical relevance of HLA-ABDR broad antigen and eplet matching for predicting acute rejection after kidney transplantation.Background: HLAMatchmaker determines structurally HLA compatibility…2015 American Transplant Congress
Is Electron Microscopy Adding a Diagnostic Advantage in the Evaluation of Renal Allograft Biopsies for Antibody Mediated Rejection (AMR)?
Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.
Some electron microscopy (EM) findings have been consistently associated with antibody mediated microvascular injury; however, no large studies have been performed examining the concrete advantage…2015 American Transplant Congress
CHBP Suppresses Acute Rejection by Inhibition Maturation of Dendritic Cells though Jak-2/STAT3/SOCS1 Signal in Rat Kidney Transplantation
Background. Renal acute rejection (AR) affects both allografts and recipients survival. We recently synthesized a novel proteolysis-resistant cyclic helix B peptide (CHBP), which exerts promising…2015 American Transplant Congress
Role of Innate Immune Cells in Chronic Allograft Loss and Novel Strategies to Target Them
Despite remarkable improvements in short term transplant survival, the long-term outcome of allografts remains poor in the clinic, and most transplants are eventually lost due…2015 American Transplant Congress
The Occurrence of v- Lesions Is Not Associated With Decreased Graft Survival
Intimal arteritis (v-lesions) in kidney transplant biopsies has been believed to have major prognostic and diagnostic significance. We assessed the relationship of v-lesions to prognosis…2015 American Transplant Congress
Glucose Chemical Exchange Saturation Transfer MRI of Acute Renal Allograft Rejection
Purpose: During acute rejection episodes large amounts of immune cells infiltrate renal grafts, leading to inflammation accompanied by an increased glucose metabolism.Given these circumstances we…2015 American Transplant Congress
De Novo Donor-Specific HLA Antibodies After Kidney Transplantation Are Associated With Donation After Circulatory Death and HLA-DQ Mismatch
Introduction: De novo donor-specific HLA-antibodies (dnDSA) have been associated with rejection and inferior kidney graft survival. The purpose of this study was to investigate the…2015 American Transplant Congress
Immune-Mediated Injury in Kidney Transplant Recipients Treated With Alemtuzumab Induction and a Steroid Avoidance Protocol
McGill University Health Centre, Montreal, Canada.
Study purpose: We evaluated short-term clinical and immunological outcomes of kidney transplant recipients who received alemtuzumab induction and a steroid-avoidance protocol.Methods: This is a retrospective…2015 American Transplant Congress
Allograft Enterectomy as a Life-Saving Procedure and Salvage for Retransplantation
Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: Allgraftectomy after solid organ transplantation is usually performed as a palliative therapy. After isolated intestinal transplantation (IIT), allograft enterectomy is sometimes necessary as a…2015 American Transplant Congress
ABO Incompatible Simultaneous Liver-Kidney Transplant With Positive Crossmatch. A Case Report
INTRODUCTION: Donor Specific (DS) antibodies and ABO incompatibility remain major immunological barriers in organ transplantation. Clinical evidence suggest the liver can protect a kidney from…
American Transplant Congress abstracts