2015 American Transplant Congress
De Novo Donor-Specific HLA Antibodies After Kidney Transplantation Are Associated With Donation After Circulatory Death and HLA-DQ Mismatch
Introduction: De novo donor-specific HLA-antibodies (dnDSA) have been associated with rejection and inferior kidney graft survival. The purpose of this study was to investigate the…2015 American Transplant Congress
Immune-Mediated Injury in Kidney Transplant Recipients Treated With Alemtuzumab Induction and a Steroid Avoidance Protocol
McGill University Health Centre, Montreal, Canada.
Study purpose: We evaluated short-term clinical and immunological outcomes of kidney transplant recipients who received alemtuzumab induction and a steroid-avoidance protocol.Methods: This is a retrospective…2015 American Transplant Congress
Allograft Enterectomy as a Life-Saving Procedure and Salvage for Retransplantation
Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: Allgraftectomy after solid organ transplantation is usually performed as a palliative therapy. After isolated intestinal transplantation (IIT), allograft enterectomy is sometimes necessary as a…2015 American Transplant Congress
ABO Incompatible Simultaneous Liver-Kidney Transplant With Positive Crossmatch. A Case Report
INTRODUCTION: Donor Specific (DS) antibodies and ABO incompatibility remain major immunological barriers in organ transplantation. Clinical evidence suggest the liver can protect a kidney from…2015 American Transplant Congress
Moderate Rejection Episode of Face Transplant After mTOR Conversion to Preserve Renal Function
1University of Maryland School of Medicine, Baltimore; 2New York Medical University, New York City.
Face and hand vascularized composite allografts (VCA) have demonstrated durable graft survivals with conventional immunosuppression but with the appearance of renal dysfunction. Management strategies that…2015 American Transplant Congress
Evaluation of Preformed Anti-HLA Antibody of "Unknown Origin" after Kidney Transplant in a Brazilian Center
Background: The use of single antigen beads assay (SAFB) for the detection of anti-HLA antibodies (Abs) may reveal the presence of Abs in individuals without…2015 American Transplant Congress
Single Center Experience of C4d Staining of Kidney Transplant Biopsies
Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.
Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…2015 American Transplant Congress
Vitamin D Supplementation and Acute Rejection Following Kidney Transplantation
1Barnes-Jewish Hospital, St. Louis, MO; 2Washington University in St. Louis, St. Louis, MO.
Purpose: Low serum levels of vitamin D have been associated with deleterious effects post-transplantation, including increased risk of rejection. Low serum vitamin D levels are…2015 American Transplant Congress
Clinical Subclassifiation of ABMR Phenotypes: Recognizing Variation in Presentation
Alberta Transplant Applied Genomics Centre, Edmonton, Canada.
The diagnosis of ABMR in kidney transplants is based on ptc-, g- and cg-lesions in biopsies and donor-specific antibody (DSA). To recognize the actual phenotypes…2015 American Transplant Congress
Prediction of Acute Antibody Mediated Rejection in Antibody Incompatible Renal Transplantation Using Machine Learning for Wide Data
The dynamic field of renal transplantation is characterised by limited access to data, the high cost of equipment and underlying complexity of immunological responses to…
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