2016 American Transplant Congress
CD45RO+/CD62L- Effector Memory T Cells Mediate Depletion Resistant Allograft Rejection in Intestinal Transplant Recipients.
MedStar Georgetown Transplant Institute, Washington DC.
A. A high risk of acute cellular rejection (ACR) is one of the key factors limiting intestinal transplantation (ITx). An extremely poor prognosis is related…2016 American Transplant Congress
Frequency and Utility of Donor-Specific Antibody Testing in Simultaneous Liver Kidney Transplant.
Introduction: The risk of antibody mediated rejection (AMR) in simultaneous liver kidney (SLK) recipients is thought to be lower than in kidney alone patients due…2016 American Transplant Congress
Tocilizumab as Treatment for Persistent Chronic Active Antibody Mediated Rejection.
Columbia University Medical Center, NYC.
Intro: CAAMR is an increasingly recognized cause of renal allograft failure with limited treatment options. Many patients with CAAMR have engagement of both T and…2016 American Transplant Congress
Influence of Country-Associated Geographical Variables in the Ouctomes of Kidney Transplantation in Patients with HIV-Infection.
Objective: To evaluate effects of geographical factors on demography, clinical management and evolution of two cohorts of HIV-infected KT recipients.Methods: Observational, retrospective cohort study including…2016 American Transplant Congress
Factors Mediating Kidney Rejection in Patients of Simultaneous Liver-Kidney Transplants.
BACKGROUND & AIM: Kidney grafts in simultaneous liver-kidney (SLK) recipients are considered to be immunologically protected due to hepatic tolerance, although recent studies have alternatively…2016 American Transplant Congress
Benefit of Protocol Biopsies in Pediatric Kidney Transplant Patients.
Medical University of South Carolina, Charleston.
BackgroundMuch debate exists over the utility of protocol biopsies for pediatric kidney transplant recipients. While there is a growing amount of literature on the utility…2016 American Transplant Congress
First Clinical Experience with Belatacept in 3 Hand Transplanted Patients.
Study purposeBelatacept (CTLA4Ig) is an emerging treatment in solid organ transplantation. Effects on the development of donor specific antibodies (DSA) as well as its clinical…2016 American Transplant Congress
DEPTOR Inhibits mTORC1 in CD4+ T Cells and Increases Treg Function by Stabilizing Foxp3 Expression.
The modulation of PI-3K/Akt-induced signaling is critical for CD4+ Treg homeostasis and stability. Moreover, activation of PI-3K/Akt/mTOR signals within T cell subsets is associated with…2016 American Transplant Congress
The Impact of Ritonavir-Boosted Protease Inhibitors and Non-Depleting Antibody Induction on Outcomes in HIV-Infected Kidney Transplant Recipients.
Mount Sinai Hospital, New York.
Background: One-year rejection rates in HIV-infected kidney transplant recipients range from 15-40%, compared to overall rejection rates of 10% in HIV-negative patients. Protocols for immunosuppression…2016 American Transplant Congress
Mapping Heterogeneity in Antibody-Mediated Rejection Using Molecular Phenotypes and Archetype Analysis.
Archetype analysis is a method for identifying new relationships among samples without subdividing them into classes, finding a limited number of archetypical cases and calculating…
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