2016 American Transplant Congress
The Effect of Donor-Recipient Relationship on the Immunologic Outcome in Living Kidney Transplantation.
Nephrology, Charite Campus Mitte, Berlin, Germany.
Background. Presensitization and degree of HLA-matching influences immunologic outcome and kidney graft survival. Thus the donor-recipient relationship may influence incidence of immunologic events and outcome…2016 American Transplant Congress
A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?
Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.
Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…2016 American Transplant Congress
Transcriptome Profiles in Peripheral Blood of Kidney Graft Recipients.
The discovery of sensitive noninvasive diagnosis and the development of immune management in the renal allograft recipients are required for long-term graft survival. Although the…2016 American Transplant Congress
Eomesodermin Expression by CD8+ Alloreactive T Cells in Human and Nonhuman Primate Allograft Recipients.
Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.
Background:The transcription factor Eomesodermin (Eomes) is critical in the maintenance of antigen-specific memory T cells (Tmem). We have shown previously that prolonged kidney allograft survival…2016 American Transplant Congress
Pre-Existing Diabetes Mellitus Type 2 and Insufficiently Controlled Post-Transplant HbA1c in Kidney Transplantation.
Nephrology, Charité University, Berlin, Germany.
Background Limited data have been reported on the outcomes of kidney transplant recipients (KTR) with pre-existing diabetes mellitus type 2 (preDM) at time of transplantation…2016 American Transplant Congress
The Bacterial Enzyme IdeS, Inhibits HLA Antibody-Mediated NK Cell Activation and Cell Cytotoxicity (ADCC) In Vitro.
Background: Antibody-mediated rejection (ABMR) is a major obstacle for successful transplantation in HLA-sensitized patients. ADCC is one of the primary mechanisms for ABMR. IdeS cleaves…2016 American Transplant Congress
The Combined Effect of Acute Rejection and De Novo Donor-Specific Antibodies on Kidney Allograft Survival.
Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO.
While dnDSA is associated with graft loss in multiple studies, the clinical context in which dnDSA develops and contributes to graft loss is less well…2016 American Transplant Congress
Alloimmunity Through Non-HLA Epitopes in Kidney Transplantation.
Introduction: An unexpected diversity in the human genome has been identified including more than 2,500 nonsynonymous single nucleotide polymorphisms (nsSNP) and up to 20 homozygous…2016 American Transplant Congress
A Model to Explore the Potential Budget Impact of a Novel Screening Tool for the Detection of Subclinical Rejection Among Kidney Transplant Patients.
1Immucor, Inc, Waukesha, WI; 2Avalare Health, LLC, Washington, DC.
Background: Acute rejection among kidney transplant patients is common, with ~10% of individuals experiencing acute rejection within the first year and rising to 16-17% at…2016 American Transplant Congress
Pediatric Heart Transplantation Across a Positive Cross-Match Is Associated with High Rates of AMR but No Difference in Short Term Graft Loss, Dysfunction and Death (CTOTC-04 study).
Sensitization is common in pediatric heart transplant (HT) candidates. Waitlist mortality is high if a prospective -ve CDC-crossmatch (XM) is required, but HT across a…
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