ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Rejection"

  • 2022 American Transplant Congress

    Steroid-Free Living Donor Liver Transplantation Using Rabbit Antithymocyte Globulin Induction Reduces Incidence of Acute Cellular Rejection

    C. Eymard1, S. Naik1, J. Eason2

    1James D Eason Transplant Institute, Memphis, TN, 2University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: The efficacy of steroid-free immunosuppression protocols using rabbit antithymocyte globulin (RATG) induction with tacrolimus minimization has previously been described in deceased donor liver transplantation.…
  • 2022 American Transplant Congress

    Peripheral Blood Immune Cell Profiles of Corneal Transplant with and without Acute Rejection

    J. Hjortdal1, M. Griffin2, C. C. Murphy3, S. Brouard4, N. Degauque4

    1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark, 2National University of Ireland, Galway, Galway, Ireland, 3Royal Victoria Eye and Ear Hospital, Dublin, Ireland, 4Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France

    *Purpose: Acute rejection (AR) of allogeneic corneal transplantation (CT) has a profound effect on subsequent graft survival, indicating that immunological damage is often not fully…
  • 2022 American Transplant Congress

    A Three-gene Peripheral Blood Potential Diagnosis Signature Associated With Autophagy For Antibody-mediated Rejection In Renal Transplantation

    Y. Wang, Y. Xu, H. Zhang, X. Hu

    Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

    *Purpose: Antibody-mediated rejection (AMR) is emerging as a major cause of graft loss in renal transplantation. Nowadays, non-invasive diagnosis of AMR with high accuracy is…
  • 2022 American Transplant Congress

    De Novo DSA in the Setting of Stable Allograft Function is a Benign Finding

    R. J. Knight, E. A. Graviss, D. T. Nguyen, T. N. Eagar, S. G. Yi, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: We sought to determine the long-term outcome of renal allografts that developed de novo DSA (dnDSA) in the setting of stable renal function.*Methods: A…
  • 2022 American Transplant Congress

    Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience

    A. Altheaby1, R. Algain2, R. Salem2, A. Alotaibi2, K. Owaidah2, M. Tawahri1, M. Shaheen3, Z. Arabi4

    1Nephrology, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 2Internal Medicine, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 3King Saud Bin Abdulaziz for Health Sciences, Riyadh, Saudi Arabia, 4Renal Transplant, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia

    *Purpose: The expanding supply-demand mismatch between organs available for transplantation and patients in need led to the growth of transplant tourism. In our study, we…
  • 2022 American Transplant Congress

    Predictors of Response to Belatacept Conversion in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection

    D. Kumar1, R. Winstead1, H. Iftikhar1, R. Minniti1, S. Khorsandi1, J. Christensen1, I. Yakubu1, I. Moinuddin1, L. Kamal1, P. Halloran2, G. Gupta1

    1Virginia Commonwealth University, Richmond, VA, 2University of Alberta, Edmonton AB, AB, Canada

    *Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause of kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. We…
  • 2022 American Transplant Congress

    Impact of Induction Immunosuppression on Renal Recovery in Adult Liver Transplant Recipients – A Single Center Experience

    T. Zurick1, D. Bruno2, D. Kumar3, R. Winstead1, C. Song1, A. Brown1, S. Sterling1, I. Yakubu1

    1Pharmacy, VCU Health System, Richmond, VA, 2Transplant Surgery, VCU Health System, Richmond, VA, 3Transplant Nephrology, VCU Health System, Richmond, VA

    *Purpose: Renal dysfunction after liver transplantation (LT) is associated with increased morbidity and mortality. Early exposure to calcineurin inhibitors (CNI) is a risk factor for…
  • 2022 American Transplant Congress

    Clinical Significances Of Anti-collagen Type I And Type Iii Antibodies In Antibody-mediated Rejection

    S. Park1, S. Yang1, K. Moon1, J. Ha1, Y. Kim1, E. Song1, H. Lee2

    1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: It is important to determine the clinical significance of non-human leukocyte antigen (HLA) antibodies and their association with antibody-mediated rejection (ABMR) of kidney allografts.*Methods:…
  • 2022 American Transplant Congress

    Very Low Frequency of Pathological Findings in One-Year Protocol Biopsies of Low-Risk Kidney Transplant Recipients – Results from the Nordic Protocol Biopsy Study

    I. Helanterä1, C. Dörje2, F. Ortiz3, A. Varberg Reisæter2, C. Hammarstrøm2, J. Lauronen4, A. Räisänen-Sokolowski5, A. J. Haugen6, M. Lempinen1, A. Åsberg2, G. Mjøen2

    1Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland, 2Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, 3Nephrology, Helsinki University Hospital, Helsinki, Finland, 4Histocompatibility Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland, 5Department of Pathology, Helsinki University Hospital, Helsinki, Finland, 6Medical Department, Bærum Hospital, Bærum, Norway

    *Purpose: The clinical usefulness of kidney graft protocol biopsies have been debated. We studied the frequency of borderline and T-cell-mediated rejection (TCMR) in one-year protocol…
  • 2022 American Transplant Congress

    Hypomethylated Regulatory Regions in Immune Signaling Genes Characterize Rejection Prone Pediatric Liver Transplant (LT) Recipients

    R. Sindhi1, X. Shao2, C. Ashokkumar1, T. Pastinen3, R. Sindhi4

    1Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2National Research Council Canada, Digital Technologies Research Centre, National Research Council Canada, Ottawa, ON, Canada, 3University of Missouri-Kansas City School of Medicine, Kansas City, MO, 4Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    *Purpose: Transcriptional regulation of LT rejection may reveal novel predictive and therapeutic targets. To identify signaling pathways which are differentially regulated by DNA methylation in…
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