2016 American Transplant Congress
A Novel Intra-Abdominal Cooling System Prevents Graft Warming During Implantation for Robotic-Assisted Renal Transplantation.
Background and objectiveRobotic kidney transplantation is minimal invasive and leads to decreased surgical site infection. In this stetting, warm ischemia time remains a valid concern.…2015 American Transplant Congress
Proteasome Activation During Renal Cold Storage and Transplantation: A Novel Pathway for Mitochondrial Destruction?
Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR.
Purpose: Renal cold storage (CS) is considered to be an alloantigen-independent risk factor for long-term transplant outcome. The precise molecular mechanisms responsible for CS-related renal…2015 American Transplant Congress
The Immunogenic Perlecan Fragment LG3 Is Released Through Apoptotic Extracellular Vesicles Downstream of Caspase-3 Activation
LG3, a C-terminal fragment of perlecan, has been implicated in aggravation of renal allograft rejection and vascular injury. LG3 is known to be produced at…2015 American Transplant Congress
Inflammasome Activation in Hepatocytes and Kupffer Cells Orchestrates the Hepatotoxic Effect of Bile Acids and Can Be Potential Target in the Management of Cholestatic Liver Injury
Purpose: Cholestatic liver injury (CLI) is commonly associated with many hepatobiliary diseases and substantially increases the peri-operative morbidity and mortality in liver surgery and transplantation.…2015 American Transplant Congress
A Novel Signaling Approach for the Prevention of Ischemia/Reperfusion Injury (IRI)
Mitochondrial reactive oxygen species (ROS) produced during early reperfusion are important triggers for the development of ischemia/reperfusion injury (IRI). However, antioxidants yielded little clinical benefit…
American Transplant Congress abstracts