Articles tagged "Rat"

2015 American Transplant Congress
Anti-Apoptotic But Not Mitotic Effects of 3,3',5-triiodo-l-thyronine in the Liver of Brain Dead Rats
A. van Erp,¹ R. Rebolledo,² J. Wiersema-Buist,¹ P. Ottens,¹ H. Leuvenink,¹ P. Romanque.²
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Surgery, University of Chile, Santiago, Chile.
Thyroid hormone treatment in brain dead organ donors has been extensively studied and applied in the clinical setting. However, its effectiveness remains controversial due to…
2015 American Transplant Congress
Effects of Mast Cell Stabilization on the Development of Aspiration-Induced Fibrosis in a Rat Model
E. Sapmaz, Z. Sun, J.-C. Chang, N. Sanders, S. Bell, M. Everett, Z. Holzknecht, W. Parker, R. Davis, S. Lin.
Surgery, Duke University Medical Center, Durham, NC.
Gastric fluid aspiration affects a great number of lung transplant recipients, both before and after the transplant, and can contribute significantly to morbidity and mortality.…
2015 American Transplant Congress
Lifor Organ Preservation Solution Protects Pulmonary Microvasculature in a Rat Model of Ex Vivo Lung Perfusion and Transplantation
T. Okamoto,^1,3 A. Yasuda,^1,2 D. Mathisen,^1,3 H. Ott.^1,3
¹Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; ²Department of Anesthesiology, Massachuetts General Hospital, Boston, MA; ³Department of Surgery, Massachuetts General Hospital, Boston, MA.
A. Ex Vivo Lung Perfusion (EVLP) has emerged as an innovative method for lung preservation. Microvascular dysfunction and breakdown of endothelial barrier during EVLP are…
2015 American Transplant Congress
Gradual Warming Up Perfusion Post Static Cold Storage Reduces Renal Injury
P. Mahboub,^3,1 P. Ottens,¹ R. Ploeg,² P. Martins,³ H. Leuvenink.¹
¹Surgery, UMCG, Groningen, Netherlands; ²Surgery, University of Oxford, Oxford, United Kingdom; ³Surgery, UMass, Worcester, MA.
We hypothesize that the sudden warm reperfusion after Cold Storage [CS] is detrimental for the graft and we therefore evaluated different warming-up procedures before reperfusion.Methods:Rat…
2015 American Transplant Congress
Mesenchymal Stem Cell Therapy to Improve Functional Outcome in Vascular Composite Allotransplantation (VCA)
S. Salgar, J. Bingham, M. DeHart, J. Tercero, T. Brown.
Madigan Army Medical Center, Tacoma.
Introduction: Although over 200 VCA including hand and face transplants have been performed worldwide with encouraging graft survival outcomes, long-term success with motor and sensory…
2015 American Transplant Congress
Effects of the Allo-Immune Response On Nerve Regeneration in Vascularized Composite Allotranplantation
S. Tuffaha,¹ J. Budihardjo,¹ P. Afrooz,² K. Sarhane,¹ R. Jindal,² D. Cooney,¹ G. Brandacher,¹ W. Lee.¹
¹Plastic and Reconstructive Surgery, Johns Hopkins Medical Institutions, Baltimore, MD; ²Plastic and Reconstructive Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.
Purpose: Unlike solid organ transplantation, VCA relies on adequate nerve regeneration for graft function. There is a lack of understanding regarding how the alloimmune response…
2015 American Transplant Congress
Experimental Study Using Contrast-Enhanced Ultrasonography to Evaluate Rat Chronic Allograft Nephropathy Model and the Relationship Between Hemodynamic Parameters and Renal Allograft Fibrosis
Q. Zhang,¹ Z. Yu,² Y. Xu,¹ S. Zeng,¹ W. Xue,¹ X. Hu.¹
¹Urology Department, Beijing ChaoYang Hospital Capital Medical University, Beijing, China; ²Ultrasound Department, Beijing ChaoYang Hospital Capital Medical University, Beijing, China.
Objectives:To quantitatively analyze the changes of hemodynamic characteristics in renal allograft at different stages of a rat chronic allograft nephropathy [CAN]model and the relationship between…