ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Rat"

  • 2015 American Transplant Congress

    Gradual Warming Up Perfusion Post Static Cold Storage Reduces Renal Injury

    P. Mahboub,3,1 P. Ottens,1 R. Ploeg,2 P. Martins,3 H. Leuvenink.1

    1Surgery, UMCG, Groningen, Netherlands; 2Surgery, University of Oxford, Oxford, United Kingdom; 3Surgery, UMass, Worcester, MA.

    We hypothesize that the sudden warm reperfusion after Cold Storage [CS] is detrimental for the graft and we therefore evaluated different warming-up procedures before reperfusion.Methods:Rat…
  • 2015 American Transplant Congress

    Mesenchymal Stem Cell Therapy to Improve Functional Outcome in Vascular Composite Allotransplantation (VCA)

    S. Salgar, J. Bingham, M. DeHart, J. Tercero, T. Brown.

    Madigan Army Medical Center, Tacoma.

    Introduction: Although over 200 VCA including hand and face transplants have been performed worldwide with encouraging graft survival outcomes, long-term success with motor and sensory…
  • 2015 American Transplant Congress

    Effects of the Allo-Immune Response On Nerve Regeneration in Vascularized Composite Allotranplantation

    S. Tuffaha,1 J. Budihardjo,1 P. Afrooz,2 K. Sarhane,1 R. Jindal,2 D. Cooney,1 G. Brandacher,1 W. Lee.1

    1Plastic and Reconstructive Surgery, Johns Hopkins Medical Institutions, Baltimore, MD; 2Plastic and Reconstructive Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Purpose: Unlike solid organ transplantation, VCA relies on adequate nerve regeneration for graft function. There is a lack of understanding regarding how the alloimmune response…
  • 2015 American Transplant Congress

    Experimental Study Using Contrast-Enhanced Ultrasonography to Evaluate Rat Chronic Allograft Nephropathy Model and the Relationship Between Hemodynamic Parameters and Renal Allograft Fibrosis

    Q. Zhang,1 Z. Yu,2 Y. Xu,1 S. Zeng,1 W. Xue,1 X. Hu.1

    1Urology Department, Beijing ChaoYang Hospital Capital Medical University, Beijing, China; 2Ultrasound Department, Beijing ChaoYang Hospital Capital Medical University, Beijing, China.

    Objectives:To quantitatively analyze the changes of hemodynamic characteristics in renal allograft at different stages of a rat chronic allograft nephropathy [CAN]model and the relationship between…
  • 2015 American Transplant Congress

    Identification of miRNAs Associated With Induced Tolerance to Allografts

    M. Vitalone, L. Wei, C. Esquivel, S. Busque, O. Martinez, S. Krams.

    Surgery-Transplantation, Stanford University School of Medicine, Stanford, CA.

    Introduction: Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. Total lymphoid irradiation (TLI) is part of…
  • 2015 American Transplant Congress

    Type III Phosphodiesterase (PDE3) Inhibitor Improves Survival Rate After Ischemia Reperfusion Injury of the Liver in Rats

    T. Fujii,1 H. Obara,2 N. Fujimura,2 K. Matsubara,2 Y. Kitagawa.2

    1Surgery, Inagi Municipal Hospital, Tokyo, Japan; 2Surgery, Keio University School of Medicine, Tokyo, Japan.

    BackgroundPDE3 inhibitor (Cilostazol) has long been used as a potent inhibitor of platelet aggregation and thrombosis. Recently, there have been a report on the protective…
  • 2015 American Transplant Congress

    Stem Cell and Novel Biologic Therapies to Enhance Functional Recovery in Limb Transplantation

    K. Kniery, M. DeHart, T. Brown, S. Salgar.

    Surgery/Clinical Investigation, Madigan Army Medical Center, Tacoma, WA.

    Introduction: Unlike visceral organ transplants, vascular composite allotransplantation such as limb and face require successful nerve regeneration and reinnervation of graft motor and sensory targets…
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