2017 American Transplant Congress
36 Hours of Ex-Vivo Warm Cellular Perfusion of Swine Liver Using the Organ Care System (OCS™) Liver with Excellent Functional, Metabolic and Histological Outcomes.
Cold storage preservation results in ischemia/reperfusion injury to the donor liver, it lacks any resuscitative or assessment capabilities. The OCS™ Liver maintains livers in a…2017 American Transplant Congress
Results of the Initial Phase of the Portable Organ Care System (OCS™) Liver PROTECT Pivotal Trial.
PurposeThe OCS Liver PROTECT Trial is a prospective, international, randomized controlled trial to evaluate the impact of using portable ex-vivo warm, oxygenated blood perfusion using…2017 American Transplant Congress
Early Results of the UK REVIVE Trial for Ex-Vivo Liver Warm Blood Perfusion of DCD and DBD Livers Using the Portable Organ Care System (OCS™) Liver Technology.
Hepatobiliary and Transplant Surgery, The Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Purpose:TheOCS Liver REVIVE Trial is a single-arm prospective trial to evaluate the safety and performance of OCS™ Liver system to preserve and assess DCD and…2017 American Transplant Congress
Delayed Renal Implantation Improves Survival Following Simultaneous Liver-Kidney Transplantation in High Acuity Recipients.
1Houston Methodist Hospital, Houston, TX; 2David Geffen School of Medicine at UCLA, Los Angeles, CA
OBJECTIVES:Simultaneous liver-kidney transplantation (SLKT) improves survival for liver transplant (LT) recipients with renal dysfunction (RD); however, simultaneous transplant risks KT futility in high acuity recipients.…2017 American Transplant Congress
Use of Pulsatile Perfusion Modifies the Effect of Delayed Graft Function on Graft Failure.
While the causal mechanisms remain elusive, delayed graft function (DGF) has been associated with graft failure in recipients of deceased-donor kidneys. Pulsatile perfusion pump use…2017 American Transplant Congress
Direct Comparison of Hypothermic and Normothermic Organ Preservation in a Porcine Ex-Vivo Kidney Model.
Background: Hypothermic machine perfusion is a well established method for deceased donor organ preservation as well as pre-transplant assessment and preconditioning. Recent translational and clinical…2016 American Transplant Congress
Ex-Vivo Normothermic Perfusion for Assessment of High Risk Deceased Donor Kidneys for Transplantation.
Surgery, University of California-Davis, Sacramento, CA.
Despite the organ shortage, many procured deceased donor kidneys are deemed too high risk for failure and discarded. Ex-vivo normothermic perfusion (EVNP) may be useful…2016 American Transplant Congress
Associations of Perfusate Biomarkers and Pump Parameters with Delayed Graft Function and Deceased-Donor Kidney Allograft Function.
Hypothermic machine perfusion (HMP) is increasingly used in deceased-donor kidney transplantation, but controversy exists regarding the value of perfusion biomarkers and pump parameters for assessing…2015 American Transplant Congress
Delayed Kidney Transplant in Combined Liver-Kidney Transplantation Improves GFR and Patient Survival
Transplant Division, Department of Surgery, Indiana University, Indianapolis.
Background: Patients requiring combined liver-kidney transplantation (LKTx) are at risk for worse outcomes compared to LTx and KTx alone due to severity of illness and…2015 American Transplant Congress
Do Pre-Procurement Factors Affect Vascular Resistance During Pulsitile Perfusion of Deceased Donor Kidneys?
Background: Pulsatile perfusion (PP) of explanted deceased donor kidneys can improve early function after transplantation, as compared to static cold flushing and storage. High vascular…
American Transplant Congress abstracts