ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Protocol biopsy"

  • 2020 American Transplant Congress

    The 1st Year Posttransplant Course Reliably Predicts Kidney Graft Survival up to 15 Years Using a Machine Learning-Based Modeling Approach

    W. Gwinner, M. Gietzelt, R. Hanna, A. A. Khalifa, M. Hallensleben, M. Marschollek, H. Haller, J. H. Braesen, I. Scheffner

    Hannover Medical School, Hannover, Germany

    *Purpose: Identification of patients at risk for graft failure can improve individual surveillance and early therapeutic interventions. We used a well-documented patient cohort to establish…
  • 2019 American Transplant Congress

    C1q Dominant Deposits in Renal Transplant Biopsies Are Not Associated with Allograft Dysfunction

    A. Babu1, S. Williamson2, N. Khoury1, M. Safwan1, A. Patel1

    1Transplant Institute, Henry Ford Hospitals, Detroit, MI, 2Pathology Surgical, Henry Ford Hospitals, Detroit, MI

    *Purpose: Complement deposition in renal allograft biopsies and native kidneys may represent an ongoing inflammatory process. We studied the significance of incidental finding of predominant…
  • 2019 American Transplant Congress

    Clinical Features of IgA Nephropathy Recurrence after Kidney Transplantation

    H. HIGUCHI1, K. Hotta2, H. Harada1, Y. Wada1, A. Mitsuke1, D. Iwami2, N. Shinohara2

    1Urology and Kidney transplant surgery, Sapporo General Hospital, Sapporo, Japan, 2Urology, Hokkaido University, Sapporo, Japan

    *Purpose: Recurrence of IgA nephropathy (IgAN) is one of the major cause of kidney graft loss. The clinical features of disease recurrence after kidney transplantation…
  • 2019 American Transplant Congress

    Mesangiopathic Glomerulonephritis in Kidney Transplants

    G. Towns, G. Agarwal, S. Ong, R. Mundra, C. Kew

    UAB, Birmingham, AL

    *Purpose: Describe higher than anticipated prevalence of Mesangiopathic Glomerulonephritis on surveillance biopsies.*Methods: Review of all surveillance biopsies from September 2014 through September 2018 for presence…
  • 2019 American Transplant Congress

    When to Hold: Apixaban in Renal Transplant Recipients

    V. H. Do1, D. Haakinson2, K. D. Belfield1

    1Yale New Haven Hospital, New Haven, CT, 2Yale School of Medicine, New Haven, CT

    *Purpose: Renal transplant recipients (RTRs) may develop deep venous thrombosis (DVT), pulmonary embolism (PE), or atrial fibrillation requiring treatment with oral anticoagulation. There is limited…
  • 2019 American Transplant Congress

    Impact of Six-Month Surveillance Biopsies and Monitoring on 2-Year Outcomes in Pediatric Renal Transplant Recipients

    J. Lyons1, D. Ranch2, R. Hall1, P. Maxwell1, K. Hitchman2, B. Crowther1

    1University Health System, The University of Texas at Austin, College of Pharmacy, Pharmacotherapy Division, Austin, TX, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 2University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX

    *Purpose: Evaluate the utility of surveillance biopsies on post-transplant outcomes.*Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011-10/2015 was conducted.…
  • 2019 American Transplant Congress

    Effect of Race and Antibody-Mediated Injury on Outcomes after Early Subclinical Inflammation

    E. P. Kasik, M. E. Seifert, M. Bernard, G. Agarwal, H. Fatima, R. Gaston, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, F. Rosenblum, G. Towns, R. B. Mannon

    University of Alabama, Birmingham, AL

    *Purpose: The impact of subclinical inflammation (SCI) on transplant outcomes has been variable, based on previous studies in homogeneous cohorts with relatively low immunologic risk.…
  • 2019 American Transplant Congress

    Recurrent Diabetic Nephropathy Despite Intensive Glycemic Control: An Observational Cohort Study

    M. Coemans, E. Van Loon, E. Lerut, D. Kuypers, B. Sprangers, P. Gillard, C. Mathieu, G. Verbeke, M. Naesens

    KU Leuven, Leuven, Belgium

    *Purpose: After kidney transplantation, recurrence of diabetic nephropathy has been reported. The presentation and kinetics of recurrent diabetic nephropathy and its risk factors remain however…
  • 2019 American Transplant Congress

    Humoral Immune Responses to Kidney Associated Non-HLA Antigens is Not Associated with Progression to Chronic Immune Injury in Kidney Transplant Recipients

    S. Sukumaran Nair1, R. Ravichandran2, R. Heilman1, A. Jaramillo1, D. Ramon1, M. Buras1, B. Kaplan1, T. Mohanakumar2

    1Mayo Clinic, Phoenix, AZ, 2St. Joseph’s Hospital, Phoenix, AZ

    *Purpose: Development of donor specific anti-HLA (DSA) although is a known risk factor for Chronic immune injury (CII), it is undetectable in many patients with…
  • 2019 American Transplant Congress

    IL-6R Blockade with Tocilizumab Increases Tregs and Decreases Early Graft Inflammation in Kidney Transplant Recipients: Results of a Randomized Controlled Trial

    S. Chandran, J. Leung, Z. Laszik, Q. Tang, C. Hu, M. Joanes, F. Vincenti

    UCSF, San Francisco, CA

    *Purpose: IL-6, a proinflammatory cytokine and key regulator of Treg/Th17 balance, is strongly associated with renal graft rejection. We hypothesized that IL-6 blockade with tocilizumab…
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