2020 American Transplant Congress
Impact of Variation in Histological Assessments and Their Impact on Clinical Trial Enrollment and Endpoints – Preliminary Report of The Gen04 Study
*Purpose: Renal allograft histology is often used as inclusion criteria for clinical trials. This includes Gen04, which is an NIH sponsored multi-center clinical trial involving…2020 American Transplant Congress
Cost-Effectiveness of Protocol Biopsies in Kidney Transplantation
Medicine, University of Pittsburgh, Pittsburgh, PA
*Purpose: To perform an economic evaluation of protocol biopsies in kidney transplantation*Methods: We used a Markov decision analytical model (Figure 1) to compare the following…2020 American Transplant Congress
The Impact of DSA Screening in Stable Kidney Transplant Recipients in the 1st Year Post-Transplant
*Purpose: The importance of Donor Specific Antibody (DSA) as a screening tool within the 1st year post kidney transplant in stable patients remains unclear. We…2020 American Transplant Congress
Time-Zero Histology Correlates with Donor Characteristics but Does Not Predict Short-Term Outcomes in Kidney Transplantation
University of Alabama School of Medicine, Birmingham, AL
*Purpose: Time-zero biopsies provide important information about baseline histology but their clinical utility compared to other non-invasive predictors is unclear. Our center performs universal time-zero…2020 American Transplant Congress
Torque Teno Virus Level for Risk Stratification of Subclinical Graft Rejection at 12 Months after Kidney Transplantation – An Prospective Observational Cohort Study
Medical University Vienna, Vienna, Austria
*Purpose: Non-invasive monitoring strategies are insufficient to detect patients at risk for subclinical graft rejection after kidney transplantation. The highly prevalent and non-pathogenic Torque Teno…2020 American Transplant Congress
Impact of Focal Cortical Necrosis (CN) in Preimplantation Biopsy (PBx) on Outcomes after Deceased Donor Kidney Transplantation
*Purpose: The data on outcomes of focal CN in PBx after deceased donor transplantation is sparse. We studied the prognostic value of focal CN on…2020 American Transplant Congress
1 -Year Protocol Biopsies in Pediatric Kidney Transplant Children: Are Unfavorable Histological Lesions Related to No Adherence?
*Purpose: In adults with kidney transplantation (KT), histological findings in surveillance biopsies at 1-year post KT are independent correlate to short and long-term graft survival.…2020 American Transplant Congress
The 1st Year Posttransplant Course Reliably Predicts Kidney Graft Survival up to 15 Years Using a Machine Learning-Based Modeling Approach
Hannover Medical School, Hannover, Germany
*Purpose: Identification of patients at risk for graft failure can improve individual surveillance and early therapeutic interventions. We used a well-documented patient cohort to establish…2020 American Transplant Congress
The UCSF Cardiovascular Risk after Kidney Transplantation (CARAKTER) Study
1UCSF, San Francisco, CA, 2UC Davis, Sacramento, CA
*Purpose: We established the UCSF CARAKTER (Cardiovascular Risk After Kidney Transplantation) Study in order to evaluate risk factors for cardiac disease onset and progression in…2020 American Transplant Congress
Impact of Timing of T Cell Mediated Rejection in the First Year after Kidney Transplantation
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: To evaluate the impact of timing of T-cell mediated rejection (TCMR) occurrence in the first year after kidney transplantation (KT).*Methods: Single center retrospective cohort…
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