2020 American Transplant Congress
Unusual Case of Delayed Onset Proteinuria in AT1R Antibody Mediated Rejection
Nephrology and Hypertension, University of Louisville, Louisville, KY
*Purpose: Describing the nuances in treatment of Angiotensin receptor II Type I antibody mediated rejection*Methods: Complement-independent Angiotensin receptor II Type I antibodies (AT1R-Ab) have been…2020 American Transplant Congress
The Use of dd-cfDNA as a Predictive Tool for Future Proteinuria
*Purpose: Most allografts with proteinuria >1500 mg/dL have new glomerular pathology. In contrast, lower levels of proteinuria are generally associated with non-glomerular, nonspecific histologic changes.…2020 American Transplant Congress
Characterization of an Integrative Prognostic Score for US Patients Taken from the DART Study
*Purpose: iBox is a validated cloud-based software as a service (SaaS) algorithm that provides a predictive analysis of the post-transplant patient, quantifying the risk of…2020 American Transplant Congress
Unique Podocyte and Multiplex Single-Cell RNASeq Analysis of Paired Sera and Bone Marrow Samples Suggest a Role for Perturbed Hematopoeitic Progenitors in FSGS Recurrence
University of California San Francisco, San Francisco, CA
*Purpose: Focal Segmental Glomerulosclerosis (FSGS) is the most common cause of nephrotic syndrome, can lead to ESRD, and carries a high burden of recurrence risk…2020 American Transplant Congress
Early Compensatory Hypertrophy Circumvents Hyperfiltration Injury in Adult Recipients of Small Pediatric Deceased Donor Kidneys
1Mayo Clinic Alix School of Medicine, Phoenix, AZ, 2Mayo Clinic, Phoenix, AZ
*Purpose: Donor-to-recipient body weight ratios have been shown to influence kidney transplant (KT) outcomes. For small pediatric donors, this mismatch is far more pronounced and…2020 American Transplant Congress
Change in Hypertension (HTN) Guidelines in Living Kidney Donors (LKDs) and Long-Term Renal Outcomes
1Mayo Clinic Rochester, Rochester, MN, 2Mayo Clinic Rochester, Scottsdale, AZ
*Purpose: There is limited knowledge regarding the long-term renal outcomes in hypertensive LKDs. We performed a multicenter study assessing long-term outcomes with or without HTN…2020 American Transplant Congress
Clinicopathologic Features and Risk Factors of Proteinuria in Transplant Glomerulopathy: A Cross-Sectional Study
*Purpose: Proteinuria is common after transplantation. Transplant Glomerulopathy (TG), one of the main causes of post-transplant proteinuria, is also a major contributor to graft loss.…2020 American Transplant Congress
Accelerated Decline in Glomerular Density: An Unrecognized Pathologic Process after Kidney Transplantation
Mayo Clinic, Rochester, Rochester, MN
*Purpose: Studies in healthy adults have shown that glomerular density slowly declines with older age (-0.5% per decade), and globally sclerotic glomeruli (GSG) slowly increase…2019 American Transplant Congress
Shroom3 Regulates Glomerular Hypertrophy after Uninephrectomy via mTOR
Mount Sinai School of Medicine, New York, NY
*Purpose: A Shroom3 intronic risk locus & Shroom3 protein have been associated with increased fibrosis but reduced albuminuria in recipients of allografts with the risk…2019 American Transplant Congress
Significance of Histopathologic Features for Predicting Progression in Patients with Transplant Glomerulopathy
National Clinical Research Center of Kidney Diseases, Nanjing, China
*Purpose: Transplant glomerulopathy (TG) represents a major cause of long-term allograft failure and is the leading cause of overall post-transplant proteinuria. We aimed to determine…
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