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Articles tagged "Prophylaxis"

  • 2020 American Transplant Congress

    Early versus Delayed Initiation of CMV Prophylaxis after Liver Transplantation

    M. Magid, J. Byrns, J. Gommer, Z. Yang, M. Harris

    Duke University Hospital, Durham, NC

    *Purpose: To determine the incidence of CMV DNAemia in early (prior to post-op day 7) versus delayed prophylaxis in liver transplant recipients.*Methods: Retrospective, single-center study…
  • 2020 American Transplant Congress

    Evaluation of an Intervention to Reduce Underdosing of Valganciclovir for Primary Prophylaxis of Cytomegalovirus Infection in Donor Seropositive/Recipient Seronegative Kidney and Liver Transplant Recipients

    L. Al Bizri1, Z. S. Chaudhry2, A. Vahia2, J. Williams2, J. C. Lemos-Ramirez3, B. Summers4, A. Patel5, S. Nagai6, O. Abreu Lanfranco2, M. Ramesh2, R. Del Busto2, G. Alangaden2

    1Internal Medicine, Henry Ford Health System, Detroit, MI, 2Infectious Disease, Henry Ford Health System, Detroit, MI, 3Department of Transplant Infectious Disease, Memorial Regional Hospital, Hollywood, FL, 4Central Pharmacy, Henry Ford Health System, Detroit, MI, 5Nephrology, Henry Ford Health System, Detroit, MI, 6Surgery Transplant, Henry Ford Health System, Detroit, MI

    *Purpose: Valganciclovir (VCV) prophylaxis is used to prevent primary cytomegalovirus (CMV) infection in CMV donor seropositive/recipient seronegative (D+/R-) solid organ transplant recipients (SOT). We examined…
  • 2020 American Transplant Congress

    Twice Weekly Valganciclovir for Cytomegalovirus Infection Prophylaxis in Kidney Transplant Recipients with Delayed Graft Function on Hemodialysis

    S. A. Mehta1, A. Katz2, R. Dieter2, P. Jen2, J. Siegfried2, J. Papadopoulos2, T. Lewis2

    1Infectious Diseases, NYU Langone Health, New York, NY, 2Pharmacy, NYU Langone Health, New York, NY

    *Purpose: The incidence of cytomegalovirus (CMV) remains high in the first year following kidney transplantation. Valganciclovir (VGC) is commonly prescribed in the early post-operative period…
  • 2020 American Transplant Congress

    Incidence of Oropharyngeal and Esophageal Candidiasis in Adult Kidney Transplant Recipients Receiving Nystatin versus No Prophylaxis

    L. Moreno1, K. Klein1, C. Long2, R. Hall1, J. Nelson1

    1Pharmacotherapy and Pharmacy Services, Pharmacotherapy Division, University Health System, The University of Texas Health Science Center at San Antonio, The University of Texas at Austin, College of Pharmacy, San Antonio, TX, 2Pharmacotherapy and Pharmacy Services, Pharmacy Practice, University Health System, University of the Incarnate Word Feik School of Pharmacy, San Antonio, TX

    *Purpose: The purpose of this study is to evaluate the need for nystatin prophylaxis for oropharyngeal (OPC) and esophageal Candidiasis (EC) in adult kidney transplant…
  • 2019 American Transplant Congress

    Pneumocystis Prophylaxis in Solid Organ Transplant Recipients at Two Large Transplant Centers from 2015-2016: Why Not Trimethoprim-Sulfamethoxazole?

    J. M. Lum1, V. Athans2, I. Echenique3, C. E. Koval1

    1Infectious Diseases, Cleveland Clinic Floundation, Cleveland, OH, 2Infectious Diseases, University of Pennsylvania, Philadelphia, PA, 3Infectious Diseases, Cleveland Clinic Florida, Weston, FL

    *Purpose: Trimethoprim-sulfamethoxazole (T/S) is the drug of choice for Pneumocystis jirovecii pneumonia (PJP) prophylaxis (ppx) after solid organ transplant (SOT). Perceived side effects may lead…
  • 2019 American Transplant Congress

    Impact of a Short Duration, Narrow Spectrum Perioperative Antibiotic Prophylaxis Regimen on Multi-Drug Resistant Surgical Site Infections in Adult Orthotopic Liver Transplantation

    M. John1, K. Maguigan1, D. Schain2, E. Thomas3, P. Efron4, J. Nelson5

    1Pharmacy, UF Health Shands Hospital, Gainesville, FL, 2Infectious Diseases, UF Health Shands Hospital, Gainesville, FL, 3Transplant Surgery, University Health System, San Antonio, TX, 4Surgery, UF Health Shands Hospital, Gainesville, FL, 5Pharmacy, University Health System, San Antonio, TX

    *Purpose: There is a paucity of data defining the optimal agent and timing of peri-operative antimicrobial prophylaxis in orthotopic liver transplantation (OLT). The purpose of…
  • 2019 American Transplant Congress

    Retrospective Evaluation of Dapsone Prophylaxis Complications in Kidney Transplant Recipients

    S. Hamel1, V. Johnson2, D. Johnson2, E. Blumberg3, R. Bloom4, J. Trofe-Clark2

    1Pharmacy, Vanderbilt Univ. Medical Center, Nashville, TN, 2Pharmacy, Hospital of the Univ. of Pennsylvania, Philadelphia, PA, 3Infectious Diseases, Univ. of Pennsylvania, Philadelphia, PA, 4Renal, Univ. of Pennsylvania, Philadelphia, PA

    *Purpose: Secondary options for Pneumocystis Jirovecii pneumonia (PJP) prophylaxis in kidney transplant recipients (KTRs) include atovaquone or dapsone. Atovaquone use may be limited by cost/side…
  • 2019 American Transplant Congress

    Low-Dose Valacyclovir Prophylaxis for Cytomegalovirus Infection in Renal Transplant Recipients with Intermediate Risk

    A. Velioglu1, H. Arikan1, E. Asicioglu1, S. Alagoz2, N. Seyahi2, S. Tuglular1, C. Ozener1

    1Nephrology, Marmara University School of Medicine, İstanbul, Turkey, 2Nephrology, Istanbul University, Cerrahpasa Medical School, İstanbul, Turkey

    *Purpose: According to recent guidelines ganciclovir or valganciclovir chemoprophylaxis is recommended for all kidney transplantation (KT) recipients (except for D-/R- serology) for preventing cytomegalovirus (CMV)…
  • 2019 American Transplant Congress

    Real World Data Support International Consenus Guidelines on Management of CMV after Kidney Transplantation

    A. Asberg, G. B. Kro, A. V. Reisæter, A. Hartmann, K. Midtvedt

    Oslo University Hospital - Rikshospitalet, Oslo, Norway

    *Purpose: Cytomegalovirus (CMV) naïve kidney transplant recipients (R-) transplanted with an organ from a CMV positive donor (D+) are at high risk for CMV disease.…
  • 2019 American Transplant Congress

    Pharmacokinetics of Innovative versus Generic Valganciclovir in Kidney Transplant Recipients

    I. Parra-Avila1, A. Cohen-Bucay1, J. Alberu2, G. Castañeda-Hernandez3, L. E. Morales-Buenrostro1

    1Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición, Ciudad de Mexico, Mexico, 2Transplant, Instituto Nacional de Ciencias Médicas y Nutrición, Ciudad de Mexico, Mexico, 3Pharmacology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de Mexico, Mexico

    *Purpose: In kidney transplant recipients (KTR), cytomegalovirus (CMV) is a common viral infection associated with significant morbidity and mortality. In the absence of prophylaxis, CMV…
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