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American Transplant Congress abstracts

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Articles tagged "Prophylaxis"

  • 2021 American Transplant Congress

    Probiotic Protocol to Reduce Perioperative Infection After Liver Transplantation

    M. Jorgenson1, Q. Yang2, D. Yang2, G. Leverson2, C. Saddler2, J. Smith2, N. Safdar2, L. Fernandez2, D. Al-Adra2

    1UW Health, Madison, WI, 2UW School of Medicine and Public Health, Madison, WI

    *Purpose: Evaluate efficacy and safety of a probiotic preparation to reduce perioperative infection in patients undergoing liver transplant surgery*Methods: Adult patients receiving liver transplantation from…
  • 2021 American Transplant Congress

    PDSA Model to Improve Pneumococcal Vaccine Adherence Among Kidney Transplant Candidates

    J. M. Ramakrishna, L. Brumble, C. R. Libertin

    Division of Infectious Diseases, Mayo Clinic, Florida, Jacksonville, FL

    *Purpose: Streptococcus pneumoniae infections occur in solid organ transplant patients at a rate of 146 per 100,000 persons per year versus 11.5 per 100,000 persons…
  • 2021 American Transplant Congress

    Perioperative Anidulafungin Combined with Triazole Prophylaxis for the Prevention of Early Invasive Candidiasis in Lung Transplant Recipients

    E. Sartain1, K. Schoeppler1, B. Crowther1, J. B. Smith2, M. Abidi3, T. J. Grazia4, M. Steele2, T. Gleason2, K. Porter2, A. Gray2

    1University of Colorado Skaggs School of Pharmacy, Aurora, CO, 2Division of Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO, 3Division of Infectious Disease, University of Colorado, Denver, CO, 4Baylor University Medical Center, Dallas, TX

    *Purpose: Invasive candidiasis (IC) is a substantial cause of morbidity and mortality in lung transplant recipients (LTRs). Post-operative factors, such as prolonged hospital stay, central…
  • 2021 American Transplant Congress

    Methenamine for the Prevention of Recurrent UTIs Post-Renal Transplant

    A. Bigness1, S. Mohamed2, S. Mandala1, N. Khodieva2, K. Robichaux3, H. Mohammed1, J. Buggs4, A. Kumar1, A. Brueckner5, L. Bowman5

    1Morsani College of Medicine, University of South Florida, Tampa, FL, 2College of Public Health, University of South Florida, Tampa, FL, 3Honors College, University of South Florida, Tampa, FL, 4Transplant Surgery, Tampa General Hospital, Tampa, FL, 5Department of Pharmacology, Tampa General Hospital, Tampa, FL

    *Purpose: Urinary tract infections (UTIs) are a highly prevalent postoperative complication in kidney transplant recipients (KTRs), occurring in approximately 34% of patients. The common method…
  • 2021 American Transplant Congress

    Outcomes Among CMV Mismatched and Highly Sensitized Kidney Transplant Recipients Who Develop Leukopenia or Neutropenia

    S. Brar1, R. Berry2, A. Raval3, Y. Tang3, F. Vincenti2, N. Skartsis2

    1University of British Columbia, Vancouver, BC, Canada, 2University of California, San Francisco, San Francisco, CA, 3Merck and Co., Inc., Kenilworth, NJ

    *Purpose: Kidney transplant recipients (KTRs) who receive antiproliferative agents for immunosuppression and valganciclovir for CMV prophylaxis are at high risk of developing leukopenia and neutropenia.…
  • 2021 American Transplant Congress

    Management of Drug Interactions During Protocolized Implementation of Posaconazole Immediately Post Heart Transplant

    G. Waldman, C. Rogers Marks, J. Clark, A. Woo, L. Irwin, A. Gerlach, G. D. Lewis, J. A. Fishman

    Massachusetts General Hospital, Boston, MA

    *Purpose: Posaconazole (POSA) is a strong CYP3A4 inhibitor known to increase tacrolimus exposure by up to 4-fold. Initiation requires empiric tacrolimus dose adjustment and close…
  • 2021 American Transplant Congress

    Unquantified Blips Lead to CMV Slips – Post Transplant CMV Monitoring in High Risk Kidney Transplant Recipients

    A. T. Payne1, J. G. Timpone2, A. Gilbert2, B. Thomas2, B. K. Lindner2

    1Georgetown University School of Medicine, Washington, DC, 2Medstar Georgetown University Hospital, Washington, DC

    *Purpose: Cytomegalovirus (CMV) is a significant cause of morbidity, mortality, and graft failure after solid organ transplantation, with high risk (D+/R-) patients being the highest…
  • 2020 American Transplant Congress

    The Safety and Effectiveness and of Isoniazid Empirical Prophylaxis Compared to Screening Based Prophylaxis Post Lung Transplantation

    G. B. Korayem1, R. S. Almaghrabi2, N. I. AlSuhaibani1, G. S. AlSwailem1, M. A. AlShammari1, D. A. Aleissa3

    1Pharmacy Practice Department, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia, 2Section of Infectious Diseases, Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, 3Transplant Clinical Pharmacist, Pharmaceutical Care Division, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

    *Purpose: Even though guidelines recommend using isoniazid (INH) for TB prophylaxis depending on donors and recipients’ screening tests, previous studies supported its use in all…
  • 2020 American Transplant Congress

    Alternate Triazole Therapy for Breakthrough Invasive Fungal Disease in Lung Transplant Recipients on Triazole Prophylaxis

    A. Abbas, H. Hassouna, F. Marco Canosa, K. D. Brizendine

    Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Invasive fungal diseases (IFD) are a leading cause of infection related morbidity and mortality in lung transplant (LT) recipients. Data regarding outcomes of breakthrough…
  • 2020 American Transplant Congress

    Isavuconazole (ISA) versus Voriconazole (VOR) Prophylaxis (px) in Lung Transplant Recipients (LTR)

    P. Samanta, C. J. Clancy, R. V. Marini, R. Rivosecchi, E. K. McCreary, R. K. Shields, B. A. Falcione, A. Viehman, L. Sacha, E. J. Kwak, F. P. Silveira, L. Clarke, M. H. Nguyen

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: IFI is a significant complication following lung transplant (LT). VOR was universal antifungal (AF) px in our LT program from 2004-09/2015, at which time…
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