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American Transplant Congress abstracts

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Articles tagged "Prophylaxis"

  • 2022 American Transplant Congress

    Therapeutic Drug Monitoring of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Patients

    S. Sial, K. Cunningham, J. Moore, C. Dagostino, K. Lang, C. Kane

    Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Lung transplant patients are at an increased risk for invasive fungal infections and often require prophylaxis post-transplant, routinely including posaconazole at our institution. These…
  • 2022 American Transplant Congress

    Assessment of Letermovir as Universal Prophylaxis for Cytomegalovirus Infection in Lung Transplant Recipients

    L. F. Borges, T. Sparkman, K. Gutierrez, J. Banbury

    UAB Hospital, Birmingham, AL

    *Purpose: Cytomegalovirus (CMV) poses a significant concern in the post-operative management of lung transplant (LT) recipients. Current recommended prophylactic strategies with ganciclovir (GCV) or valganciclovir…
  • 2022 American Transplant Congress

    Preemptive Therapy in Cytomegalovirus (CMV) Seropositive Donor to Seronegative Recipient Liver Transplants

    J. Revollo, E. Aldag, K. Cooper, B. Noell, V. Casingal, K. Gajurel

    Transplant, Atrium Health's Carolinas Medical Center, Charlotte, NC

    *Purpose: To evaluate if a preemptive therapy strategy can prevent CMV disease and induce CMV seroconversion.*Methods: Observational data collection for CMV D+/R- adult liver transplant…
  • 2022 American Transplant Congress

    Risk for Loss of Hepatitis B Surface Antibody or Hepatitis B Reactivation in Kidney Transplant Recipients Receiving Lymphocyte Depleting Induction

    K. Paplaczyk1, C. Kane1, M. Kapugi1, K. Lang1, K. Cunningham1, C. D'Agostino1, J. Boike2

    1Pharmacy, Northwestern Memorial Hospital, Chicago, IL, 2Transplant Hepatology, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Although used in over 60% of kidney transplant recipients, the impact of lymphocyte depleting induction on hepatitis B surface antibody (HBsAb) and hepatitis B…
  • 2022 American Transplant Congress

    Letermovir for Prophylaxis of Cytomegalovirus After Solid Organ Transplantation: A Single-Center, Observational Study

    T. N. Bullard1, C. A. Moore2, J. Dasigi2, L. M. Sacha2, C. A. Iasella3, K. A. Shimko2, E. K. McCreary4, F. P. Silveira4

    1Massachusetts General Hospital, Boston, MA, 2UPMC, Pittsburgh, PA, 3Univ of Pittsburgh, Pittsburgh, PA, 4Univ of Pittsburgh and UPMC, Pittsburgh, PA

    *Purpose: Cytomegalovirus (CMV) infections cause significant complications post-transplant; however, prophylactic medications are often limited by toxicities. Letermovir is a novel terminase inhibitor specific to CMV…
  • 2022 American Transplant Congress

    Recurrent Cytomegalovirus and the Role of Secondary Prophylaxis in Heart and Lung Transplant Recipients

    S. N. Finder1, K. Harrison1, M. Morrison1, S. Rega2, I. Feurer2, C. Gorsline3, G. Satyanarayana3, S. Hamel1

    1Department of Pharmaceutical Sciences, Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt Transplant Center, Nashville, TN, 3Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: This study aimed to describe the incidence of cytomegalovirus (CMV) recurrence in heart and lung transplant recipients and the effect of secondary prophylaxis (SP)…
  • 2022 American Transplant Congress

    Effect of Micafungin Bridging on Prevention of Invasive Candidiasis Post Lung Transplantation

    C. Baladad1, M. Converse1, K. DeSear1, S. Karimi1, E. Rubido1, G. El Helou2, T. Pasley1

    1Pharmacy, University of Florida Health, Shands, Gainesville, FL, 2Infectious Diseases, University of Florida Health, Shands, Gainesville, FL

    *Purpose: This study aims to determine the effect of micafungin, added as a bridging agent to azole antifungal prophylaxis, in lung transplantation patients with positive…
  • 2021 American Transplant Congress

    Cost-Effectiveness Analysis of Short-Duration Anti-Viral Prophylaxis for Hepatitis C Positive Donor Kidney Transplants

    I. Yakubu, Y. Zhang, S. Ijioma, N. V. Carroll, J. Patterson, R. Sterling, G. Gupta

    Virginia Commonwealth University Health System, Richmond, VA

    *Purpose: Trials describing 4-12 week courses of direct-acting anti-viral drugs (DAAs) to treat hepatitis C virus (HCV) transmission from infected donors to uninfected kidney transplant…
  • 2021 American Transplant Congress

    Practice Patterns in Pneumocystis Jirovecii Pneumonia Prophylaxis in Solid Organ and Bone Marrow Transplant Recipients

    S. Cao, K. Khalil, F. Cirrone, S. Mehta

    NYU Langone Transplant Institute, New York, NY

    *Purpose: Trimethoprim-sulfamethoxazole (TMP-SMX) is the preferred agent for pneumocystis jirovecii pneumonia (PJP) prophylaxis in solid organ transplant (SOT) and bone marrow transplant (BMT); however, adverse…
  • 2021 American Transplant Congress

    Utilizing Risk Factors to Guide Prevention of Invasive Fungal Infections in Liver Transplant Recipients

    K. Fitton, A. Chan, C. Truax, B. Sirandas, T. Larson, L. Smith, A. Carlson

    University of Utah Health, Salt Lake City, UT

    *Purpose: Invasive fungal infection (IFI) after liver transplant (LT) is associated with significant morbidity and mortality. The optimal antifungal prophylaxis regimen has not been defined.…
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