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American Transplant Congress abstracts

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Articles tagged "Prophylaxis"

  • 2015 American Transplant Congress

    Prophylaxis of Post-Renal Transplant Urinary Tract Infection With Fosfomycin Trometamol. A Controlled, Randomized Clinical Trial. (Intermediate Analysis)

    J. Arreola-Guerra,1 L. Morales-Buenrostro,3 M. Arvizu-Hernandez,3 E. Mancilla-Urrea,2 P. Maria,2 M. Vilatoba-Chapa,1 J. Alberu,1 J. Sifuentes-Osornio.1

    1Transplantation, National Institute of Medical Sciences an Nutrition Salvador Zubirán, Mexico City, Mexico; 2Transplantation, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico; 3Nephrology and Mineral Metabolism, National Institute of Medical Sciences an Nutrition Salvador Zubirán, Mexico City, Mexico.

    Background: Urinary tract infection (UTI) is the most frequent infection during post-transplant (pTR) follow-up. Aim: To compare the incidence of UTI during the first 6…
  • 2015 American Transplant Congress

    Renal Function Difference Between Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy and HBIG Combined With Entecavir in Liver Recipients

    J. Lee,1,2 J. Lee,1,2 J. Lee,3 M. Kim,1,2 M. Ju,1,2 G. Choi,1,2 J. Choi,1,2 S. Kim,1,2 D. Joo.1,2

    1Department of Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seroul, Korea; 2Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; 3Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.

    Background: To reduce the HBV reinfection after liver transplantation, anti-hepatitis B immunoglobulin (HBIG) alone or combination with antiviral nucleotide analogues are usually used regimen. However,…
  • 2015 American Transplant Congress

    The Impact of Preoperative Antimicrobial Prophylaxis on Device-Related Infections in Recipients of Long-Term Mechanical Circulatory Support (MCS)

    I. El Lakkis,1 K. Lietz,2 C. Derber,1 U. Kelly,1 C. Wilson,1 A. Hoedt,2 P. Bourasssa,2 B. Smith,2 M. McGrath,2 J. Herre,2 M. Mooney.1

    1Eastern Virginia Medical School, Norfolk, VA; 2Sentara Norfolk General Hospital, Norfolk, VA.

    Purpose: Although preoperative antimicrobial prophylaxis is recommended for patients undergoing long-term MCS device implantation, there is a lack of consensus as to the optimal preoperative…
  • 2015 American Transplant Congress

    Favorable Long-Term Outcome of Late-Onset CMV Disease in D+R- Kidney Transplant Recipients Treated With Universal Prophylaxis

    H. Kaminski,1 L. Couzi,1,2 I. Garrigue,3,4 J. Déchanet-Merville,2 P. Merville.1,2

    1Nephrologie-Transplantation-Dialyse, CHU Bordeaux, Bordeaux, France; 2Unité Mixte de Recherche 5164, Centre National de la Recherche Scientifique, Bordeaux, France; 3Laboratoire de Virologie, CHU Bordeaux, Bordeaux, France; 4Unité Mixte de Recherche 5234, Centre National de la Recherche Scientifique, Bordeaux, France.

    Based on last international guidelines, both universal prophylaxis and preemptive strategies are viable approaches for the prevention of cytomegalovirus (CMV) disease after organ transplantation. Universal…
  • 2015 American Transplant Congress

    Implementation of Evidence-Based Guidelines for Cytomegalovirus Prevention in Pediatric Solid Organ Transplantation

    L. Danziger-Isakov, T. Hemmelgarn, R. Kohli, D. Lazear, M. Lake, J. Goebel, C. Castleberry, J. Courter, S. Kacoshis, M. Schecter, D. Witte, E. Clark, J. Bucuvalas.

    Cincinnati Children's, Cincinnati.

    Optimal strategies to prevent cytomegalovirus (CMV) disease after pediatric solid organ transplantation (SOT) in a cost effective manner are uncertain. We evaluated the frequency of…
  • 2015 American Transplant Congress

    Incidence and Characteristics of CMV Infection in High Risk (D+R-) Kidney Transplant Recipients and the Utility of Monthly Surveillance After Routine Prophylaxis

    M. Bhattarai, C. Puttarajappa, G. Mour, C. Wu, P. Sood, N. Shah, R. Mehta, A. Tevar, S. Hariharan.

    Internal Medicine, University of Pittsburgh, Pittsburgh, PA.

    Cytomegalovirus (CMV) infection is the most common opportunistic viral infection after renal transplantation. Optimal duration of antiviral prophylaxis and the role of post prophylaxis surveillance…
  • 2015 American Transplant Congress

    Low Dose Valganciclovir Prophylaxis Following Renal Transplantation With Steroid Free Immunosuppression

    J. Chen,1 A. Shah,2 M. Sauer,1 T. Taber,3 A. Sharfuddin,3 M. Yaqub,3 D. Mishler,3 J. Powelson,4 W. Goggins.4

    1Pharmacy, IU Health, Indianapolis; 2Surgery, Thomas Jefferson University, Philadelphia; 3Nephrology, Indiana University School of Medicine, Indianapolis; 4Surgery, Indiana University School of Medicine, Indianapolis.

    AST ID guidelines recommend a valganciclovir (VGCV) prophylaxis dose of 900 mg daily for patients with CrCL > 60 mL/min with reduced dose for renal…
  • 2015 American Transplant Congress

    The Role of Antiviral Prophylaxis for the Prevention of Epstein-Barr Virus (EBV) Associated Post-Transplant Lymphoproliferative Disease (PTLD) in Solid Organ Transplant Recipients: A Systematic Review

    M. AlDabbagh,1,2 M. Gitman,3 D. Kumar, A. Humar, C. Rotstein, S. Husain.1,3

    1Medicine, Division of Infectious Diseases, University Health Network, Toronto, On, Canada; 2Pediatrics, Division of Infectious Diseases, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Saudi Arabia; 3Multi-Organ Transplant Unit, University Health Network, Toronto, ON, Canada.

    Background The role of antiviral prophylaxis in EBV seronegative solid organ transplant recipients receiving organs from seropositive donors for prevention of PTLD remains controversial. We…
  • 2015 American Transplant Congress

    Deep Surgical Site Infections (dSSI) After Liver Transplantation (LTx): Emergence of Multiple-Drug Resistant (MDR) Pathogens

    J. Viehman,1 L. Clarke,1 R. Shields,2 C. Clancy,2,3 M. Nguyen.1,2

    1University of Pittsburgh Medical Center, Pittsburgh, PA; 2University of Pittsburgh, Pittsburgh, PA; 3VA Pittsburgh Health System, Pittsburgh, PA.

    Purpose: We described the epidemiology, microbiology and outcomes of dSSI after LTx.Methods: We performed a single center retrospective study of 332 consecutive patients undergoing LTX…
  • 2015 American Transplant Congress

    Efficacy of Low Dose Chemoprophylaxis for Coccidioidomycosis Infection in Liver Transplantation Recipients

    R. El Ramahi,2 S. Habib,1 S. Rosen,3 S. Farran,3 C. Walker,3 J. Shubeilat,4 S. Yost,5 O. McCotter,6 M. Cassal,6 A. Rana,7 T. Boyer,1 T. Zangeneh.2

    1Liver Research Institute, Divisions of Gastroenterology, Hepatology and Transplantation, Department of Medicine, University of Arizona, Tucson, AZ; 2Division of Infectious Disease, Department of Medicine, University of Arizona, Tucson, AZ; 3Internal Medicine Residency Program, Department of Medicine, University of Arizona, Tucson, AZ; 4Division of Infectious Disease, Department of Medicine, University of Massachusetts, Worcester, MA; 5Division of Transplantation, School of Pharmacy, University of Arizona, Tucson, AZ; 6Office of Border Health, Arizona Department of Health Services, Tucson, AZ; 7Division of Transplantation, Department of Surgery, University of Arizona, Tucson, AZ.

    Introduction:Coccidioidomycosis(CM) infection rate of 6.9% has been reported in solid organ transplantation recipients living in endemic Southwestern U.S.Aim:Assess the risk of CM infection in liver…
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