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Articles tagged "Prophylaxis"

  • 2018 American Transplant Congress

    Micafungin Prophylaxis in Liver Transplant Recipients at High Risk for Invasive Fungal Infections

    A. Nolan, N. Harriott, K. Startsman.

    Medstar Georgetown University Hospital, Department of Pharmacy, Washington, DC.

    Purpose: This study was conducted to determine the incidence of proven or probable invasive fungal infections in the first 90 days after transplant in high…
  • 2018 American Transplant Congress

    Increase in Potentially Resistant Non-Aspergillus Molds Isolated in Lung Transplant Recipients after Voriconazole and Posaconazole Prophylaxis

    M. Fung,1 J. Greenland,2,3 S. Hays,2 J. Singer,2 J. Golden,2 P. Chin-Hong.1

    1Infectious Diseases, University of California San Francisco, San Francisco, CA; 2Pulmonary and Critical Care, University of California San Francisco, San Francisco, CA.

    Background: Lung transplant recipients are at higher risk for invasive fungal infections compared to other solid organs transplant patients. Antifungal prophylaxis with mold-active azoles has…
  • 2018 American Transplant Congress

    Infection Outcomes in Solid Organ Transplant Recipients Receiving Trimethoprim-Sulfamethoxazole as Opposed to Atovaquone for Prophylaxis

    A. Drelick,1 W. Mowrey,2 G. Minamoto.3

    1Medicine, Division of Infectious Diseases, Weill Cornell Medical Center, New York, NY; 2Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY; 3Medicine, Division of Infectious Diseases, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY.

    Background: Pneumocystis jiroveci pneumonia (PJP) is an important illness amongst solid organ transplant (SOT) recipients. Trimethoprim-sulfamethoxazole (TMP-SMX) is the prophylaxis of choice based on efficacy…
  • 2018 American Transplant Congress

    Making Sense of Hepatitis B Reactivation Risk in Anti-HBc Antibody (Ab) Positive Liver Transplant Recipients

    S. Leistman,1 J. Melaragno,1 M. Dokus,2 B. Al-Judaibi,2 T. Babu.3

    1Department of Pharmacy, University of Rochester Medical Center, Rochester, NY; 2Division of Transplantation, University of Rochester Medical Center, Rochester, NY; 3Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY.

    Background: Limited data exists regarding the rates of reactivation of hepatitis B virus (HBV) in anti-HBc Ab positive orthotopic liver transplant (OLT) recipients. Protocols vary…
  • 2018 American Transplant Congress

    Val-Ganciclovir Prophylaxis Delays Onset of EBV Viremia in the First Year Post-Solid Organ Transplantation in High-Risk Patients

    S. Albatati,1 A. Sharma,2 S. Gantt,1 K. Haubrich,1 A. Wright,1 T. Blydt-Hansen.1

    1University of British Columbia, Vancouver, Canada; 2University of Manitoba, Winnipeg, Canada.

    Introduction: Donor-derived primary Epstein-Barr virus (EBV) infection poses serious risks to EBV naïve children post-solid organ transplantation, including development of EBV-related PTLD. Currently, there is…
  • 2018 American Transplant Congress

    A Retrospective Review of De Novo Coccidioidomycosis among Remote Solid Organ Transplant Recipients in Arizona

    T. Zangeneh,1 J. August,1 N. Beatty,1 K. Asbury,2 L. Mi,2 J. Blair.2

    1Medicine/Division of Infectious Diseases, University of Arizona/Banner University Medical Center/Valley Fever Center for Excellence, Tucson, AZ; 2Medicine/Division of Infectious Diseases, Mayo Clinic Hospital, Phoenix, AZ.

    Background: Solid organ transplant (SOT) recipients residing in a Coccidioides-endemic region that acquire infection are at risk for complicated and protracted infection. Following transplantation, prophylaxis…
  • 2018 American Transplant Congress

    Pneumocystis jiroveci Pneumonia (PJP) in Kidney and Pancreas Transplant Recipients in the Present Era of Routine Post-Transplant Prophylaxis: Risk Factors and Outcomes

    N. Garg, M. Jorgenson, M. Birschbach, J. Descourouez, S. Parajuli, B. Astor, A. Djamali, D. Mandelbrot.

    University of Wisconsin, Madison.

    PJP after transplant (TX) is associated with substantial morbidity and mortality. In the present era of universal and routine implementation of PJP prophylaxis (PPX) during…
  • 2018 American Transplant Congress

    Impact of Pneumocystis Prophylaxis on Incidence of Treated Urinary Tract Infections Following Kidney Transplantation

    S. Sanchez, M. Brokhof, N. Kenyon, C. Varughese, N. Alvey.

    Rush University Medical Center, Chicago, IL.

    Background: Urinary tract infection (UTI) is the most common infectious complication after kidney transplantation resulting in increased morbidity and mortality. Sulfamethoxazole[mdash]trimethoprim (SMX-TMP) is commonly used…
  • 2018 American Transplant Congress

    Standard- versus Low-Dose Valganciclovir for Cytomegalovirus Prophylaxis in Intermediate-Risk Kidney Transplant Recipients

    N. Wilson, N. Sulejmani, A. Jantz, A. Patel, B. Summers.

    Henry Ford Hospital, Detroit, MI.

    Background: Although guidelines recommend valganciclovir (VGC) 900 mg daily for cytomegalovirus (CMV) prophylaxis in solid organ transplant patients, multiple centers have reported clinical success, reduced…
  • 2018 American Transplant Congress

    Burden of Primary CMV Infections Remains High Despite Six Months Valganciclovir Prophylaxis in High-Risk Kidney Transplant Recipients

    I. Helanterä,1 F. Ortiz,2 R. Loginov,3 L. Mannonen,3 M. Lempinen,1 I. Lautenschlager.3

    1Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; 2Nephrology, Helsinki University Hospital, Helsinki, Finland; 3Virology, Helsinki University Hospital, Helsinki, Finland.

    A. Prophylaxis has mostly replaced preemptive therapy in CMV seronegative recipients of kidneys from seropositive donors (D+/R-). Primary infections occur commonly even after six months…
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