ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Preservation"

  • 2018 American Transplant Congress

    Ex-Situ Normothermic Human Upper Extremity Perfusion: Preliminary Report

    V. Fahradyan, E. Dalla Pozza, M. Madajka, K. Cho, N. Dawlagala, E. Duraes, H. Shah, S. Al-deen Said, C. Ordenana, F. Papay, A. Rampazzo, B. Bassiri Gharb.

    Plastic Surgery, Cleveland Clinic, Cleveland, OH.

    Purpose: Ischemia time remains a significant limiting factor for successful extremity replantation and transplantation. Normothermic ex-situ perfusion is a novel method of a limb preservation…
  • 2018 American Transplant Congress

    Evaluation of a Marine OXYgen Carrier (Hemo2Life®) for Organ Preservation: First Use in Kidney Transplantation in Humans

    Y. Le Meur,1 E. Morellon,2 M. Essig,3 A. Thierry,4 M. Buchler,5 S. Drouin,6 C. Deruelle,1 L. Badet,2 F. Pesteil,3 P-.O. Delpech,4 J-.M. Boutin,5 B. Barrou.6

    1Transplantation, University Hospital, Brest, France; 2Hopital Edouard Herriot, Lyon, France; 3University Hospital, Limoges, France; 4University Hospital, Poitiers, France; 5University Hospital, Tours, France; 6La Pitié Salpetrière, Paris, France.

    Preventing ischemia/reperfusion injuries (IRIs) is a major issue in organ transplantation. At present, grafts are preserved at 4[deg]C in preservation solution in order to reduce…
  • 2018 American Transplant Congress

    A Cost Analysis on Normothermic Machine Perfusion at a Single Center

    D. Pezzati, Q. Liu, H. Hassan, G. Iuppa, L. Hernandez, G. D'Amico, T. Diago Uso, B. Heghtsad, C. Miller, C. Quintini.

    General Surgery, Cleveland Clinic, Cleveland, OH.

    INTRODUCTION: Normothermic machine perfusion (NMP) for liver transplantation is a novel and promising technique.One of the concerns related to its usage is the high cost.The…
  • 2018 American Transplant Congress

    Hypothermic Oxygenated Machine Perfusion in Liver and Kidney Transplantation of Extended Criteria Donors: A Phase-1 of Clinical Trial

    M. Ravaioli,1 V. De Pace,1 M. Cescon,1 M. Del Gaudio,1 V. R. Bertuzzo,1 A. Siniscalchi,1 A. D'Errico,2 G. Comai,2 G. La Manna,2 A. D. Pinna.1

    1General Surgery and Transplantation, University of Bologna Sant'Orsola - Malpighi Hospital, Bologna, Emilia Romagna, Italy; 2Experimental Diagnostic and Specialty Medicine, University of Bologna Sant'Orsola- Malpighi Hospital, Bologna, Emilia Romagna, Italy.

    In the field of liver (LT) and kidney transplantation (KT), extended criteria donors (ECD) offer an additional organ source that is more vulnerable for early…
  • 2017 American Transplant Congress

    Cost-Effectiveness of Renal Machine Perfusion Use After Long Cold Ischemia Time.

    A. Matos,1 D. Malheiro,3 S. Morgado,1 L. Requi[acirc]o-Moura,1 M. Souza-Durão,1,2 E. Tonato,1 M. Nogueira,1 M. Borrelli,1 A. Pacheco-Silva.1,2

    1Renal Transplant, Hospital Israelita Albert Einstein, São Paulo, Brazil; 2Nephrology, Universidade Federal de São Paulo, São Paulo, Brazil; 3Health Economics Department, Hospital Israelita Albert Einstein, São Paulo, Brazil

    High cold ischemia time (CIT) and inadequate care of donors in Brazil lead to a high incidence of delayed graft function (DGF), 60%-70%, and as…
  • 2017 American Transplant Congress

    36 Hours of Ex-Vivo Warm Cellular Perfusion of Swine Liver Using the Organ Care System (OCS™) Liver with Excellent Functional, Metabolic and Histological Outcomes.

    J. Magliocca,1 J. Markmann,2 M. Abouljoud,3 M. Ghobrial,4 A. Demetris.5

    1Division of Transplant Surgery Department of Surgery, The Emory Transplant Center, Atlanta, GA; 2Department of Surgery Division of Transplantation, Massachusetts General Hospital, Boston, MA; 3Transplant Institute and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 4Surgery - General, Houston Methodist Hospital, Houston, TX; 5Department of Transplant Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA

    Cold storage preservation results in ischemia/reperfusion injury to the donor liver, it lacks any resuscitative or assessment capabilities. The OCS™ Liver maintains livers in a…
  • 2017 American Transplant Congress

    Assessment and Transplantation of Declined Human Kidneys Using Ex-Vivo Normothermic Kidney Perfusion.

    S. Hosgood,1 M. Hamed,1 A. Sawpaul,2 R. Figueiredo,2 K. Saeb-Parsy,1 C. Wilson,2 M. Nicholson.1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2Transplantation, Transplant Institute, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom

    PurposeThe aim of this study was to make more kidneys available for transplantation by using ex-vivo normothermic kidney perfusion (EVKP) technology to assess the quality…
  • 2017 American Transplant Congress

    Outcomes from a Multinational Randomised Controlled Trial Comparing Normothermic Machine Perfusion with Static Cold Storage in Human Liver Transplantation.

    D. Nasralla,1 Consortium for Organ Preservation in Europe Liver Research Group,1 R. Ploeg,1 C. Coussios,2 P. Friend.1

    1Nuffield Department of Surgical Sciences, Oxford Transplant Centre, University of Oxford, Oxford, United Kingdom; 2Department of Biomedical Engineering, University of Oxford, Oxford, United Kingdom

    Introduction:By perfusing a liver with oxygenated blood, medications and nutrients at 37oC, normothermic machine perfusion (NMP) may improve outcomes after liver transplantation when compared with…
  • 2017 American Transplant Congress

    Risk Prediction Model for Delayed Graft Function in a Cohort of Brazilian Kidney Transplantation from Deceased Donors: What You See Is Not What You Get.

    S. Costa,1,2 T. Sandes-Freitas,1,2 E. Daher,2 R. Esmeraldo.1

    1Hospital Geral de Fortaleza, Fortaleza, Brazil; 2Federal University of Ceara, Fortaleza, Brazil

    Introduction: The estimated frequency of delayed graft function (DGF) in Brazil ranges from 50 to 70%, despite deceased donor and recipient characteristics similar to those…
  • 2017 American Transplant Congress

    Development of an Automatic Regulated Normothermic Kidney Preservation Device for Long-Term Organ Perfusion.

    A. Weissenbacher,1 O. Boubriak,2 L. Lo Faro,1 R. Ploeg,1 J. Hunter,1 D. Voyce,3 N. Mikov,3 A. Cook,3 C. Coussios,2 P. Friend.1

    1Nuffield Department of Surgical Sciences, Oxford Transplant Centre, University of Oxford, Oxford, United Kingdom; 2Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom; 3OrganOx Limited, Magdalen Centre, Oxford Science Park, Oxford, United Kingdom

    BackgroundNormothermic kidney perfusion for a period of 24 hours or longer would offer significant clinical advantages. It would enable clinicians to investigate the condition of…
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