2019 American Transplant Congress
Combined Thoracic-Liver Transplants Using Normothermic Machine Perfusion for Liver Preservation: A Case Series
Henry Ford Transplant Institute, Detroit, MI
*Purpose: There is minimal data describing combined thoracic-liver transplants (tx) with normothermic machine perfusion (NMP) used for liver preservation as the thoracic tx is done.…2019 American Transplant Congress
Brief Normothermic Machine Perfusion is Superior to Cold Storage Alone – A Paired Discarded Human Kidney Analysis
1Westmead Hospital, Sydney, Australia, 2Westmead Institute for Medical Research, Sydney, Australia
*Purpose: The use of marginal has increased due to ongoing donor shortages. These kidneys have higher rates of graft discard after procurement, and also have…2019 American Transplant Congress
CEACAM1 – p38 Signaling Axis Alleviates Peri-Transplant Liver Injury: From Mouse-to-Human
1UCLA, Los Angeles, CA, 2City of Hope, Duarte, CA
*Purpose: Although CEACAM1 (CM1; carcinoembryonic antigen-related cell adhesion molecule 1; CD66a) regulates hepatic metabolism, its role in orthotopic liver transplantation (OLT) is unknown. A recent…2019 American Transplant Congress
Patient Perspectives of Informed Consent for Deceased Donor Organ Intervention Research
*Purpose: Interventions on deceased donors or their organs hold promise for increasing the quantity and quality of organs for transplantation by minimizing organ injury and…2019 American Transplant Congress
Normothermic Ex-Vivo Kidney Perfusion Preservation Consistently Improves Extreme Marginal Graft Function Compared to Hypothermic Machine Perfusion
*Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) is an emerging technique for renal graft preservation. We investigated whether NEVKP promoted improved marginal graft function compared to…2019 American Transplant Congress
A Novel Multi-Thermic, Antiseptic, and Anthropomorphic System for Ex-Vivo Face Perfusion
*Purpose: Facial disfigurement is profoundly disabling, and great relief follows resolution by facial transplantation, now a technical reality at multiple centers worldwide. However, distance between…2019 American Transplant Congress
Protection of the Donor Kidney Vascular Endothelium by Ex-Vivo Perfusion with a Pan-Caspase Inhibitor
*Purpose: Orthotopic kidney transplantation is a life-saving therapeutic option for patients with end stage organ failure. Pulsatile perfusion (PP) of deceased donor kidneys is increasingly…2019 American Transplant Congress
Perfluorocarbon (PFC) Solutions for Organ Preservation
University of Florida, Gainesville, FL
*Purpose: The current status of organ transplantation demands consideration of extended criteria (ECD) brain dead donors (DBD) as well as donation after circulatory death (DCD)…2019 American Transplant Congress
Pancreatic Extracellular Matrix Improves Human Islet Culture and Function In Vitro
Virginia Commonwealth University, Richmond, VA
*Purpose: Islet transplantation is a thriving therapy for patients with Chronic Pancreatitis and Type-1 Diabetes. Within the pancreas, the islets are surrounded by Extracellular Matrix…2018 American Transplant Congress
Ex-Vivo Subnormothermic Oxygenated Machine Perfusion of Rodent Hindlimb: Feasibility Study to Elongate Preservation Time of Vascularized Composite Allograft
PURPOSE: A pressing challenge in the field of VCA is adequate tissue preservation. Static cold preservation, successfully used in field of solid organ transplantation, greatly…
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