ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Preservation"

  • 2020 American Transplant Congress

    The Scenario of Delayed Graft Function in Brazil

    T. V. Sandes-Freitas1, M. Mazzali2, R. Manfro3, H. Tedesco-Silva4, L. Andrade5, V. Garcia6, E. Davi-Neto7, R. Esmeraldo8, C. Oliveira9, E. Lasmar10, R. Madeira11, G. Ferreira12, G. Meira13, F. Cavalcanti14, A. Bignelli15, D. Carvalho16, D. Pedroso17, L. Deboni18, A. Silva e Filho19, A. Vicari3, M. Sousa2, .. on behalf of 'DGF multicêntrico' group20

    1Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil, 2HC/UNICAMP, Campinas, Brazil, 3HCPA/UFRGS, Porto Alegre, Brazil, 4Hospital do Rim, São Paulo, Brazil, 5HC-Botucatu/UNESP, Botucatu, Brazil, 6Santa Casa de Porto Alegre, Porto Alegre, Brazil, 7HC/FMUSP, São Paulo, Brazil, 8H. Geral de Fortaleza, Fortaleza, Brazil, 9HUWC/UFC, Fortaleza, Brazil, 10H. Universitário São José, Belo Horizonte, Brazil, 11H. Felício Rocho, Belo Horizonte, Brazil, 12Santa Casa de Juiz de Fora, Juiz de Fora, Brazil, 13Santa Casa de Montes Claros, Montes Claros, Brazil, 14Real Hospital Português, Recife, Brazil, 15H. Universitário Cajuru, Curitiba, Brazil, 16H. São Francisco na Providencia de Deus, Rio de Janeiro, Brazil, 17H. Santa Isabel, Blumenau, Brazil, 18H. Municipal São José, Joinville, Brazil, 19H. Israelita Albert Einstein, São Paulo, Brazil, 20ABTO, São Paulo, Brazil

    *Purpose: Unicenter Brazilian studies reported high incidences (50-70%) of delayed graft function (DGF). This is a multicenter Brazilian study aimed to evaluate the incidence, the…
  • 2020 American Transplant Congress

    In-Depth Assessment of Ischemia/Reperfusion Injury in a Murine Model of Hindlimb Transplantation

    F. Messner1, K. Kadono2, Y. Guo1, B. Oh1, J. Kupiec-Weglinski2, G. Brandacher1

    1Department of Plastic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Surgery, Division of Liver and Pancreas Transplantation, University of California, Los Angeles, Los Angeles, CA

    *Purpose: Static cold storage (SCS) still represents the gold standard for organ and tissue preservation in transplantation. Ischemia/reperfusion injury (IRI) that occurs due to the…
  • 2019 American Transplant Congress

    Brief Normothermic Machine Perfusion is Superior to Cold Storage Alone – A Paired Discarded Human Kidney Analysis

    A. Hameed1, E. Patrick2, D. B. Lu1, C. P'ng1, M. Hu2, Y. Chew2, R. De Roo1, L. Yuen1, W. Hawthorne1, N. Rogers1, H. Pleass1

    1Westmead Hospital, Sydney, Australia, 2Westmead Institute for Medical Research, Sydney, Australia

    *Purpose: The use of marginal has increased due to ongoing donor shortages. These kidneys have higher rates of graft discard after procurement, and also have…
  • 2019 American Transplant Congress

    CEACAM1 – p38 Signaling Axis Alleviates Peri-Transplant Liver Injury: From Mouse-to-Human

    H. Hirao1, K. Nakamura1, S. Kageyama1, T. Ito1, K. Kadono1, M. Kujawski2, K. J. Dery1, R. A. Sosa1, E. F. Reed1, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec‐Weglinski1

    1UCLA, Los Angeles, CA, 2City of Hope, Duarte, CA

    *Purpose: Although CEACAM1 (CM1; carcinoembryonic antigen-related cell adhesion molecule 1; CD66a) regulates hepatic metabolism, its role in orthotopic liver transplantation (OLT) is unknown. A recent…
  • 2019 American Transplant Congress

    Patient Perspectives of Informed Consent for Deceased Donor Organ Intervention Research

    E. Gordon1, B. Knopf1, A. Mussell2, C. Phillips2, R. Veatch3, P. Abt2, P. Reese2

    1Northwestern University, Chicago, IL, 2University of Pennsylvania, Philadelphia, PA, 3Georgetown University, Washington DC, DC

    *Purpose: Interventions on deceased donors or their organs hold promise for increasing the quantity and quality of organs for transplantation by minimizing organ injury and…
  • 2019 American Transplant Congress

    Normothermic Ex-Vivo Kidney Perfusion Preservation Consistently Improves Extreme Marginal Graft Function Compared to Hypothermic Machine Perfusion

    P. Urbanellis1, M. Hamar1, I. Linares1, D. Kollmann1, S. Ganesh1, F. Oquendo1, M. Sharma1, R. John1, A. Ghanekar1, I. Mucsi1, D. Bagli2, A. Konvalinka1, L. Robinson3, M. Selzner1

    1Multi-Organ Transplantation Program, University Health Network, Toronto, ON, Canada, 2Division of Urology, The Hospital for Sick Children, Toronto, ON, Canada, 3Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada

    *Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) is an emerging technique for renal graft preservation. We investigated whether NEVKP promoted improved marginal graft function compared to…
  • 2019 American Transplant Congress

    A Novel Multi-Thermic, Antiseptic, and Anthropomorphic System for Ex-Vivo Face Perfusion

    J. W. Etra1, J. Brassil2, F. A. Chang1, S. A. Fidder1, D. S. Cooney1, G. Brandacher1

    1Johns Hopkins University School of Medicine, Baltimore, MD, 2Functional Circulation LLC, Northbrook, IL

    *Purpose: Facial disfigurement is profoundly disabling, and great relief follows resolution by facial transplantation, now a technical reality at multiple centers worldwide. However, distance between…
  • 2019 American Transplant Congress

    Protection of the Donor Kidney Vascular Endothelium by Ex-Vivo Perfusion with a Pan-Caspase Inhibitor

    R. Plenter1, S. Jain2, T. Nydam1, A. jani2

    1Transplant Microsurgery Program, University of Colorado, Aurora, CO, 2Renal Division, University of Colorado, Aurora, CO

    *Purpose: Orthotopic kidney transplantation is a life-saving therapeutic option for patients with end stage organ failure. Pulsatile perfusion (PP) of deceased donor kidneys is increasingly…
  • 2019 American Transplant Congress

    Perfluorocarbon (PFC) Solutions for Organ Preservation

    N. Battula, T. Parsons, J. Zhu, C. Giordano, A. Esnakula, B. Spiess, M. Johnson, A. Zarrinpar, K. Andreoni

    University of Florida, Gainesville, FL

    *Purpose: The current status of organ transplantation demands consideration of extended criteria (ECD) brain dead donors (DBD) as well as donation after circulatory death (DCD)…
  • 2019 American Transplant Congress

    Pancreatic Extracellular Matrix Improves Human Islet Culture and Function In Vitro

    Y. Shindo, R. Pouillot, B. M. Young, P. Link, R. L. Heise, M. F. Levy, M. A. Kanak

    Virginia Commonwealth University, Richmond, VA

    *Purpose: Islet transplantation is a thriving therapy for patients with Chronic Pancreatitis and Type-1 Diabetes. Within the pancreas, the islets are surrounded by Extracellular Matrix…
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