2016 American Transplant Congress
Hypothermic Machine Perfusion Is Also Beneficial for Deceased Donor Kidneys When Cold Ischemic Time Is Short and a Short Cold Ischemic Time Is Also Beneficial When Kidneys Are Machine Perfused.
IntroductionHypothermic machine perfusion (HMP) of deceased donor kidneys is associated with better outcome compared to static cold storage (SCS). It is generally assumed that HMP…2016 American Transplant Congress
Influence of Pancreas Import and Cold Ischemia on Outcomes Following Pancreas Transplantation.
1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC.
Proposed changes in pancreas transplant (PT) allocation may improve organ sharing but increase cold ischemia time (CIT). Methods: We performed a single center, retrospective study…2016 American Transplant Congress
Ex Vivo Perfusion of Porcine Forelimbs to Prolong Allowable Ischemia Time.
PurposeSuccessful replantation in patients suffering from traumatic amputation of one or more extremities is limited by the muscle ischemia time of 4-6h, which also holds…2015 American Transplant Congress
Hypothermic Machine Perfusion Improves the Quality of Marginal Donor Pancreata
Introduction. Pancreas or islet transplantation is considered the most effective treatment for patients with type 1 diabetes mellitus. Due to the persistent organ shortage, pancreata…2015 American Transplant Congress
Lifor Organ Preservation Solution Protects Pulmonary Microvasculature in a Rat Model of Ex Vivo Lung Perfusion and Transplantation
A. Ex Vivo Lung Perfusion (EVLP) has emerged as an innovative method for lung preservation. Microvascular dysfunction and breakdown of endothelial barrier during EVLP are…2015 American Transplant Congress
Impact of Machine Perfusion After Long Static Cold Storage On Delayed Graft Function Incidence and Duration and Time to Hospital Discharge
Our transplant center is not involved in organ harvesting and usually we receive a kidney for transplant with more then 20 hours of static cold…2015 American Transplant Congress
European ELITA ELTR Multicenter Survey On the Management of Bile Duct During Liver Procurement, Preservation and Transplantation
Background: Surgical donor/preservation/recipient factors may play a role in the development of biliary strictures. Only scarce data are described on what is the best practice…2015 American Transplant Congress
In House Oxygen Persufflation of Cold Stored Livers Versus Simple Cold Storage in Extended Criteria Liver Grafts: Results of a Randomized Controlled Clinical Trial
Two hours of end-ischemic oxygen persufflation of cold stored porcine livers regenerates cellular energy dependent pathways and improves survival after transplantation. The present trial evaluated…2015 American Transplant Congress
Correlation Between Level of Biomarkers Measured in Perfusate of Machine-Preserved ECD/DCD Kidneys and Post-Transplant Graft Function
Background:DCD and ECD kidneys are associated with higher risk of failure compare to SCD kidneys. Therefore we see increasing need to identify sensitive tool to…2015 American Transplant Congress
Profound Effect of HDAC2 Deletion on Renal Ischemia-Reperfusion Injury Is Intrinsic to the Kidney and Includes Protection Against Cold Ischemia
Introduction: Histone/protein deacetylases (HDACs) regulate gene expression by modifying chromatin accessibility and protein acetylation. We have previously found that deletion of HDAC2 protects from renal…
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