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American Transplant Congress abstracts

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Articles tagged "Preservation solutions"

  • 2020 American Transplant Congress

    Consistent Prevention of Perioperative Cardiac Xenograft Dysfunction with Non-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model

    C. E. Goerlich1, A. Singh1, D. Kaczorowski1, M. Abdullah1, B. Lewis1, I. Tatarov1, A. Hershfeld1, T. Zhang1, P. Odonkor1, A. Tabatabai1, A. Bhutta1, E. Strauss1, B. Williams1, D. Ayares2, M. Mohiuddin1

    1Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Revivicor, Blacksburg, VA

    *Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
  • 2020 American Transplant Congress

    Comparing Two Methods of Minimally-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model

    C. E. Goerlich1, A. Singh1, D. Kaczorowski1, M. Abdullah1, B. Lewis1, I. Tatarov1, A. Hershfeld1, T. Zhang1, E. Strauss1, P. Odonkor1, B. Williams1, D. Ayares2, B. Griffith1, M. Mohiuddin1

    1Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Surgery, Revivicor, Blacksburg, VA

    *Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
  • 2020 American Transplant Congress

    Early Graft Function and Intrarenal Resistant Index after Kidney Transplantation Using New Preservation Fluid (Biolasol)

    A. Kolonko1, R. Król2, J. Chudek3, L. Cierpka2, A. Więcek1

    1Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland, 2General, Vascular and Transplant Surgery, Medical University of Silesia, Katowice, Poland, 3Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice, Poland

    *Purpose: Biolasol is a newly developed preserving solution for cold organ storage prior to transplantation. The aim of this study was to compare in the…
  • 2020 American Transplant Congress

    Successful Transplantation of Murine Hearts Preserved 24h Under Subzero Ischemia Using Novel Bio-Inspired Next Generation Cryoprotectants

    B. Oh1, A. Callegari2, M. Kline2, A. Childs2, M. Iglesias Lozano1, G. Brandacher1, X. Wei2

    1Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA), Johns Hopkins University School of Medicine, Baltimore, MD, 2X-Therma Inc., Richmond, CA

    *Purpose: Extension of the organ ischemia window is of paramount importance to prolong viability of transplantable organs and to improve overall outcomes. Transport using a…
  • 2019 American Transplant Congress

    Partial Freezing: Subzero Whole Liver Preservation In The Presence Of Ice

    S. E. Cronin1, C. A. Pendexter1, R. J. deVries1, S. Kimura2, S. Ozer1, P. D. Banik1, S. Nagpal1, H. Yeh2, S. N. Tessier1, K. Uygun1, M. Toner1

    1Center for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 2Transplant Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA

    *Purpose: We aim to develop a protocol to bank organs for several days, enabling global organ matching and potentially the utilization of organs unusable with…
  • 2019 American Transplant Congress

    Supercooling Preservation Prolonged Mouse Cardiac Graft Cold Ischemia Time

    W. Que1, X. Hu1, M. Fujino1, Y. Yamada2, L. Zhong3, X. Li1

    1Division of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan, 2Technican Co., Ltd., Kanagawa, Japan, 3Department of Surgery, Shanghai General Hospital, shanghai Jiao Tong University School of Medicine, Shanghai, China

    *Purpose: Supercooling preservation techniques store a donor organ below 0°C without freezing. This has great advantages in inhibiting metabolism and preserving the organ in comparison…
  • 2019 American Transplant Congress

    Sigma-1 Receptor Agonists Are Renoprotective in a Rat Model of Kidney Transplantation

    A. Hosszu1, Z. Antal2, L. Illesy2, L. Lenart1, D. B. Balogh1, L. Wagner3, A. Vannay4, A. J. Szabo2, A. Fekete1

    1"Lendulet" Diabetes Research Group, MTA-SE, Budapest, Hungary, 21st Department of Pediatrics, Semmelweis University, Budapest, Hungary, 3Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, 4Pediatrics and Nephrology Research Group, MTA-SE, Budapest, Hungary

    *Purpose: Kidney transplantation is associated with better quality of life and reduced costs compared to dialysis, but the shortage in donor organs is a limiting…
  • 2019 American Transplant Congress

    Perfluorocarbon (PFC) Solutions for Organ Preservation

    N. Battula, T. Parsons, J. Zhu, C. Giordano, A. Esnakula, B. Spiess, M. Johnson, A. Zarrinpar, K. Andreoni

    University of Florida, Gainesville, FL

    *Purpose: The current status of organ transplantation demands consideration of extended criteria (ECD) brain dead donors (DBD) as well as donation after circulatory death (DCD)…
  • 2019 American Transplant Congress

    Evaluation of New Baskent University Preservation Solution for Liver, Kidney and Intestine Graft during Cold Ischemia: Preliminary Experimental Animal Study

    M. Haberal1, M. Kirnap1, R. Erdem2, H. Ozdemir3, M. Lux2, D. Bacanli4

    1Transplantation, Baskent University, Ankara, Turkey, 2Pharmacology, Baskent University, Ankara, Turkey, 3Pathology, Baskent University, Ankara, Turkey, 4Experimental Laboratory, Baskent University, Ankara, Turkey

    *Purpose: Despite significant advances in organ transplantation, damage caused to organs due to long cold ischemia time and perfusion solutions remains a serious hurdle. The…
  • 2019 American Transplant Congress

    Assessment of Culture/Preservation Conditions on Survival and Function of Islets

    Y. Shindo, M. F. Levy, M. A. Kanak

    Surgery, Virginia Commonwealth University, Richmond, VA

    *Purpose: Culture or preservation of human islets prior to transplantation has been adopted by various centers because it may reduce immunogenicity, suppress exocrine contamination and…
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