ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Preservation solutions"

  • 2020 American Transplant Congress

    Consistent Prevention of Perioperative Cardiac Xenograft Dysfunction with Non-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model

    C. E. Goerlich1, A. Singh1, D. Kaczorowski1, M. Abdullah1, B. Lewis1, I. Tatarov1, A. Hershfeld1, T. Zhang1, P. Odonkor1, A. Tabatabai1, A. Bhutta1, E. Strauss1, B. Williams1, D. Ayares2, M. Mohiuddin1

    1Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Revivicor, Blacksburg, VA

    *Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
  • 2020 American Transplant Congress

    Comparing Two Methods of Minimally-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model

    C. E. Goerlich1, A. Singh1, D. Kaczorowski1, M. Abdullah1, B. Lewis1, I. Tatarov1, A. Hershfeld1, T. Zhang1, E. Strauss1, P. Odonkor1, B. Williams1, D. Ayares2, B. Griffith1, M. Mohiuddin1

    1Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Surgery, Revivicor, Blacksburg, VA

    *Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
  • 2020 American Transplant Congress

    Early Graft Function and Intrarenal Resistant Index after Kidney Transplantation Using New Preservation Fluid (Biolasol)

    A. Kolonko1, R. Król2, J. Chudek3, L. Cierpka2, A. Więcek1

    1Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland, 2General, Vascular and Transplant Surgery, Medical University of Silesia, Katowice, Poland, 3Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice, Poland

    *Purpose: Biolasol is a newly developed preserving solution for cold organ storage prior to transplantation. The aim of this study was to compare in the…
  • 2020 American Transplant Congress

    Successful Transplantation of Murine Hearts Preserved 24h Under Subzero Ischemia Using Novel Bio-Inspired Next Generation Cryoprotectants

    B. Oh1, A. Callegari2, M. Kline2, A. Childs2, M. Iglesias Lozano1, G. Brandacher1, X. Wei2

    1Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA), Johns Hopkins University School of Medicine, Baltimore, MD, 2X-Therma Inc., Richmond, CA

    *Purpose: Extension of the organ ischemia window is of paramount importance to prolong viability of transplantable organs and to improve overall outcomes. Transport using a…
  • 2019 American Transplant Congress

    Assessment of Culture/Preservation Conditions on Survival and Function of Islets

    Y. Shindo, M. F. Levy, M. A. Kanak

    Surgery, Virginia Commonwealth University, Richmond, VA

    *Purpose: Culture or preservation of human islets prior to transplantation has been adopted by various centers because it may reduce immunogenicity, suppress exocrine contamination and…
  • 2019 American Transplant Congress

    New Reactive Oxygen Species Scavenger Prevents Injury in Ischemia-Reperfusion Injury Model

    N. Bath, W. Fahl, R. Redfield III

    University of Wisconsin, Madison, WI

    *Purpose: Despite the success of preservation solutions, Ischemia-Reperfusion (IR) injury remains a significant problem for all solid organ transplants. As a result, an important, unmet…
  • 2019 American Transplant Congress

    The Significance and Impact of Screening Preservation Fluid Cultures in Renal Transplant Recipients

    A. Reticker, A. Lichvar, A. Gross, E. Benedetti, S. Patel

    University of Illinois Hospital and Health Sciences System, Chicago, IL

    *Purpose: Preservation fluid (PF) is necessary to maintain organ viability but serves as a vector for infection. The utility of routine PF screening and impact…
  • 2019 American Transplant Congress

    The Effect of the Beneficial Activity of α-Lipoic Acid Treatment Depend on the Quality of the Graft Kidneys

    F. Osella1, N. Ambrosi2, G. Werber1, F. Caro2, S. Beltramino1, I. Cabrera1, G. Hilchenbach1, L. Diaz Alvarez1, C. Incardona3, E. Chuluyan2, D. Casadei1

    1Instituto de Trasplante y Alta Complejidad, Buenos Aires, Argentina, 2CEFYBO, UBA, Buenos Aires, Argentina, 3GADOR S.A., Buenos Aires, Argentina

    *Purpose: In a previous preliminary study, with a small number of patients, we observed that the treatment of the donor and the recipient with the…
  • 2019 American Transplant Congress

    Partial Freezing: Subzero Whole Liver Preservation In The Presence Of Ice

    S. E. Cronin1, C. A. Pendexter1, R. J. deVries1, S. Kimura2, S. Ozer1, P. D. Banik1, S. Nagpal1, H. Yeh2, S. N. Tessier1, K. Uygun1, M. Toner1

    1Center for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 2Transplant Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA

    *Purpose: We aim to develop a protocol to bank organs for several days, enabling global organ matching and potentially the utilization of organs unusable with…
  • 2019 American Transplant Congress

    Supercooling Preservation Prolonged Mouse Cardiac Graft Cold Ischemia Time

    W. Que1, X. Hu1, M. Fujino1, Y. Yamada2, L. Zhong3, X. Li1

    1Division of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan, 2Technican Co., Ltd., Kanagawa, Japan, 3Department of Surgery, Shanghai General Hospital, shanghai Jiao Tong University School of Medicine, Shanghai, China

    *Purpose: Supercooling preservation techniques store a donor organ below 0°C without freezing. This has great advantages in inhibiting metabolism and preserving the organ in comparison…
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