2022 American Transplant Congress
Duration of Brain Death Does Not Impact Short Term Outcomes in Kidney Transplantation
*Purpose: In animal models, brain death has been shown to induce renal injury, primarily due to ischemia, inflammation, and alterations in hemodynamics. However, donor management…2022 American Transplant Congress
Vitrification of Pancreatic Islets and Transplantation
1University of Minnesota, Minneapolis, MN, 2Mayo Clinic, Rochester, MN
*Purpose: A limitation to potential cure for diabetes through islet transplantation is insufficient islet equivalence (IEQ) from a single donor to achieve insulin independence in…2022 American Transplant Congress
Cold Pulsatile Perfusion of Donor Kidneys Varies Significantly by Procuring Organ Procurement Organization Indicating Both Over and Underutilization of This Preservation Method
Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL
*Purpose: To assess the usage and variability cold pulsatile perfusion preservation in the United States based on procuring organ procurement organization (OPO).*Methods: All donors procured…2022 American Transplant Congress
Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data
*Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…2022 American Transplant Congress
Cold Pulsatile Perfusion of Deceased Donor Kidneys Substantially Improves Kidney Utilization of Donors After Cardiac Death and Brain Dead Donors with KDPI Greater Than 60%
Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL
*Purpose: To determine trends in usage of cold pulsatile kidney perfusion and its impact on organ utilization in the United States using the SRTR database.*Methods:…2022 American Transplant Congress
Intraabdominal Hypertension in the Death by Neurologic Criteria Organ Donor
*Purpose: This study attempts to identify the incidence of abdominal compartment syndrome (ACS) within the death by neurological criteria organ donor population, provide timely intervention,…2022 American Transplant Congress
Early vs. Late Heparin Administration After Declaration of Death in DCD Donors Does Not Impact Short Term Outcomes in Kidney Transplantation
Organ Recovery, LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK
*Purpose: Kidneys from Donation after Cardiac Death (DCD) donors are well-known to have satisfactory outcomes post-transplant. In DCD donors, heparin is typically given immediately prior…2022 American Transplant Congress
Perfusate Il-6 Levels During Liver Nmp Are Predictive For Hemodynamic Response And Catecholamine Demand After Reperfusion In The Recipient
*Purpose: Normothermic liver preservation (NMP) has become a clinical routine at several transplant centres. Reperfusion-syndrome occurs less often in recipients of NMP-livers compared to cold…2022 American Transplant Congress
Xenogeneic Cross-Circulation Supports Ex Vivo Human Livers for 24 Hours
*Purpose: Despite increasing use of machine perfusion as an organ preservation and rescue technique in liver transplantation, significant organ shortages and waitlist mortality highlight a…2022 American Transplant Congress
Evaluation of UW-Based Solutions Formulated to Be Anti-Apoptotic and Neuroprotective of Retinal Ganglion Cells (RGCs) Following Whole Eye Transplantation (WET) in a Rat Model
*Purpose: As vascularized composite allotransplantation (VCA) of an intact optical system to restore vision requires overcoming RGC apoptosis caused by ischemia reperfusion injury, UW and…
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