ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Preservation"

  • 2022 American Transplant Congress

    Duration of Brain Death Does Not Impact Short Term Outcomes in Kidney Transplantation

    A. M. Hawxby1, R. Ketcham2, J. P. Orlowski3, R. A. Squires2, C. Hostetler2

    1Organ Recovery, LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK, 2LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK, 3LifeShare Transplant Donors Services, Oklahoma City, OK

    *Purpose: In animal models, brain death has been shown to induce renal injury, primarily due to ischemia, inflammation, and alterations in hemodynamics. However, donor management…
  • 2022 American Transplant Congress

    Vitrification of Pancreatic Islets and Transplantation

    J. S. Rao1, L. Zhan1, D. Tobolt1, M. Q. Slama2, N. Sethia1, Z. Han1, C. S. Dutcher1, Q. Peterson2, J. C. Bischof1, E. B. Finger1

    1University of Minnesota, Minneapolis, MN, 2Mayo Clinic, Rochester, MN

    *Purpose: A limitation to potential cure for diabetes through islet transplantation is insufficient islet equivalence (IEQ) from a single donor to achieve insulin independence in…
  • 2022 American Transplant Congress

    Cold Pulsatile Perfusion of Donor Kidneys Varies Significantly by Procuring Organ Procurement Organization Indicating Both Over and Underutilization of This Preservation Method

    D. S. Keith, E. Lessmann

    Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL

    *Purpose: To assess the usage and variability cold pulsatile perfusion preservation in the United States based on procuring organ procurement organization (OPO).*Methods: All donors procured…
  • 2022 American Transplant Congress

    Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data

    A. E. Mangus1, C. Kubal2, B. Ekser3, P. Mihaylov4, A. J. Lutz1, J. Fridell5, R. Mangus6

    1Indiana University Purdue University of Indianapolis, Indianapolis, IN, 2Indiana University Hospital, Indianapolis, IN, 3Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, 4Indiana Univ School of Medicine, Indianapolis, IN, 5Indiana University School of Medicine, Indianapolis, IN, 6Indiana University, Indianapolis, IN

    *Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…
  • 2022 American Transplant Congress

    Cold Pulsatile Perfusion of Deceased Donor Kidneys Substantially Improves Kidney Utilization of Donors After Cardiac Death and Brain Dead Donors with KDPI Greater Than 60%

    D. S. Keith, E. Lessmann

    Kidney Transplant, Ascension Sacred Heart Hospital, Pensacola, FL

    *Purpose: To determine trends in usage of cold pulsatile kidney perfusion and its impact on organ utilization in the United States using the SRTR database.*Methods:…
  • 2022 American Transplant Congress

    Intraabdominal Hypertension in the Death by Neurologic Criteria Organ Donor

    C. Schardein1, M. Moncure2, S. Craft1, S. Sanders3

    1General Surgery, University of Missouri at Kansas City, Kansas City, MO, 2Trauma and Critical Care Surgery, University of Missouri at Kansas City, Kansas City, MO, 3MTN, Kansas City, MO

    *Purpose: This study attempts to identify the incidence of abdominal compartment syndrome (ACS) within the death by neurological criteria organ donor population, provide timely intervention,…
  • 2022 American Transplant Congress

    Early vs. Late Heparin Administration After Declaration of Death in DCD Donors Does Not Impact Short Term Outcomes in Kidney Transplantation

    A. M. Hawxby, R. Ketcham, R. Squires, J. P. Orlowski, H. Solomon, C. Hostetler

    Organ Recovery, LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK

    *Purpose: Kidneys from Donation after Cardiac Death (DCD) donors are well-known to have satisfactory outcomes post-transplant. In DCD donors, heparin is typically given immediately prior…
  • 2022 American Transplant Congress

    Perfusate Il-6 Levels During Liver Nmp Are Predictive For Hemodynamic Response And Catecholamine Demand After Reperfusion In The Recipient

    A. Weissenbacher1, S. Mathis2, B. Cardini1, C. Bogensperger1, G. Putzer2, L. Gasteiger2, T. Resch1, R. Oberhuber1, D. Öfner1, T. Hell3, J. Martini2, S. Schneeberger1

    1Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria, 2Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria, 3Department of Mathematics, Faculty of Mathematics, Computer Science and Physics, University of Innsbruck, Innsbruck, Austria

    *Purpose: Normothermic liver preservation (NMP) has become a clinical routine at several transplant centres. Reperfusion-syndrome occurs less often in recipients of NMP-livers compared to cold…
  • 2022 American Transplant Congress

    Xenogeneic Cross-Circulation Supports Ex Vivo Human Livers for 24 Hours

    W. K. Wu1, R. Ukita2, Y. J. Patel2, I. A. Ziogas3, M. Cortelli2, M. Mentz2, J. R. Talackine2, S. A. Francois2, N. L. Cardwell2, J. W. Stokes2, S. P. Alexopoulos3, M. Bacchetta2

    1Hepatobiliary Surgery and Liver Transplantation; Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, 2Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, 3Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Despite increasing use of machine perfusion as an organ preservation and rescue technique in liver transplantation, significant organ shortages and waitlist mortality highlight a…
  • 2022 American Transplant Congress

    Evaluation of UW-Based Solutions Formulated to Be Anti-Apoptotic and Neuroprotective of Retinal Ganglion Cells (RGCs) Following Whole Eye Transplantation (WET) in a Rat Model

    N. J. Khatter1, Y. Wang1, B. Li1, C. R. Owens1, A. H. Jani2, C. A. Huang1, R. W. Nickells3, A. A. Su1, K. M. Washington1

    1Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Colorado, Anschutz Medical Campus, Aurora, CO, 2Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, 3Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI

    *Purpose: As vascularized composite allotransplantation (VCA) of an intact optical system to restore vision requires overcoming RGC apoptosis caused by ischemia reperfusion injury, UW and…
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