2022 American Transplant Congress
Intraabdominal Hypertension in the Death by Neurologic Criteria Organ Donor
*Purpose: This study attempts to identify the incidence of abdominal compartment syndrome (ACS) within the death by neurological criteria organ donor population, provide timely intervention,…2022 American Transplant Congress
Early vs. Late Heparin Administration After Declaration of Death in DCD Donors Does Not Impact Short Term Outcomes in Kidney Transplantation
Organ Recovery, LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK
*Purpose: Kidneys from Donation after Cardiac Death (DCD) donors are well-known to have satisfactory outcomes post-transplant. In DCD donors, heparin is typically given immediately prior…2022 American Transplant Congress
Perfusate Il-6 Levels During Liver Nmp Are Predictive For Hemodynamic Response And Catecholamine Demand After Reperfusion In The Recipient
*Purpose: Normothermic liver preservation (NMP) has become a clinical routine at several transplant centres. Reperfusion-syndrome occurs less often in recipients of NMP-livers compared to cold…2022 American Transplant Congress
Xenogeneic Cross-Circulation Supports Ex Vivo Human Livers for 24 Hours
*Purpose: Despite increasing use of machine perfusion as an organ preservation and rescue technique in liver transplantation, significant organ shortages and waitlist mortality highlight a…2022 American Transplant Congress
Evaluation of UW-Based Solutions Formulated to Be Anti-Apoptotic and Neuroprotective of Retinal Ganglion Cells (RGCs) Following Whole Eye Transplantation (WET) in a Rat Model
*Purpose: As vascularized composite allotransplantation (VCA) of an intact optical system to restore vision requires overcoming RGC apoptosis caused by ischemia reperfusion injury, UW and…2022 American Transplant Congress
Regulation of Cell Death During Cold Preservation of Marginal Human Kidneys
*Purpose: Each year thousands of kidneys from marginal donors are discarded due to an increased sensitivity to injury during cold storage and consequently a high…2022 American Transplant Congress
Addressing the Organ Shortage, Improving Transplant Longevity, and Enabling Minimally Invasive Kidney Transplantation: Development of an Intraoperative Kidney Anastomosis Facilitation and Regelation Device
*Purpose: Second warm ischemia time (SWIT) of a renal allograft during anastomosis increases rates of delayed graft function and premature graft failure. In the setting…2022 American Transplant Congress
Novel Portable Hypothermic Cardiac Preservation Device Enhances Cardiac Viability and Function of the Isolated Porcine Hearts
Vascular Perfusion Solutions, Inc, San Antonio, TX
*Purpose: Cardiac heart transplantation is the gold standard for treating end-stage heart failure; however, the list of patients waiting for heart transplants continues to increase.…2022 American Transplant Congress
Analysis of Tissue and Effluent Damage Associated Molecular Patterns Following Hypothermic Oxygenated Machine Perfusion vs Static Cold Storage in Liver Transplantation
Transplant Surgery, Rutgers New Jersey Medical School, Newark, NJ
*Purpose: Hypothermic Oxygenated Machine Perfusion (HMP-O2) results in decreased ischemia/reperfusion injury (IRI) after liver transplantation; however, the molecular pathways of protection are largely unexplored. In…2022 American Transplant Congress
Artificial Mitochondria Transfer to Mitigate Ischemic Damage in an In Vitro Model of Tubular Injury and in an Ex Vivo Porcine Model of DCD Renal Transplantation
*Purpose: We aimed at assessing whether artificial mitochondrial transfer (AMT) mitigates renal injury in an in vitro model of tubular damage and in an ex…
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