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Articles tagged "Prediction models"

  • 2015 American Transplant Congress

    The Potential Use of the Plasma Biomarker CXCL9 (MIG), Interleukin 2 Receptor alpha (IL2Rα) and SCGF-b as Predictors of Renal Graft Rejection

    C. Blume,1 S. Michael,2 N. Christine,3 H. Hermann,4 F. Christine.3

    1Technical Chemistry, Leibniz University, Hannover, Germany; 2Musculo Sceletal Reserach, University of Wuerzburg, Wuerzburg, Germany; 3Transplant Immunology, Medical School Hannover, Hannover, Germany; 4Dept. Nephrology, Medical School Hannover, Hannover, Germany.

    Background: Early detection of rejection in kidney transplantation is crucial, and predictive plasma biomarkers are highly desirable as non-invasive tests.Methods: From a cohort of 120…
  • 2015 American Transplant Congress

    The Impact of Critical Illness and Pre-Transplant Hospitalization on Cost of Liver Transplantation

    S. Knechtle, L. Brummett, S. Perez.

    Surgery, Emory University School of Medicine, Atlanta, GA.

    In order to understand the cost impact of hospitalization and ICU admission immediately prior to liver transplantation (LT), we obtained all hospital costs associated with…
  • 2015 American Transplant Congress

    Prediction of Acute Antibody Mediated Rejection in Antibody Incompatible Renal Transplantation Using Machine Learning for Wide Data

    T. Shaikhina,1 N. Khovanova,1 S. Daga,1,3 N. Krishnan,2 D. Lowe,3 D. Mitchell,1 D. Briggs,2 R. Higgins.3

    1University of Warwick, Coventry, United Kingdom; 2NHS Blood and Transplant, Birmingham, United Kingdom; 3University Hospitals Coventry and Warwickshire, Coventry, United Kingdom.

    The dynamic field of renal transplantation is characterised by limited access to data, the high cost of equipment and underlying complexity of immunological responses to…
  • 2015 American Transplant Congress

    MELD Velocity – An Early Predictor of Increased Mortality Risk

    D. Ladner,1 K. Skibba,2 J. Kang,1 B. Ho,1 A. Kho,1 L. Kulik,1 A. Daud,1 M. Abecassis,1 A. Skaro.1

    1Northwestern University, Chicago, IL; 2Rosalind Franklin University of Medicine and Science, Chicago, IL.

    INTRODUCTION: MELD is a satisfactory predictor of 3-month mortality in patients with cirrhosis. However, sub-populations of patients at increased hazard of mortality, but not well…
  • 2015 American Transplant Congress

    Multicenter Study to Develop a Novel Prediction Index for Hepatocellular Carcinoma (HCC) Recurrence After Liver Transplant (LT)

    N. Mehta,1 J. Heimbach,2 D. Harnois,3 J. Dodge,1 J. Burns,3 D. Lee,3 W. Sanchez,2 J. Roberts,1 F. Yao.1

    1UCSF, San Francisco, CA; 2Mayo Clinic, Rochester, MN; 3Mayo Clinic, Jacksonville, FL.

    Several factors have been associated with a high risk of recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT), but no reliable risk score has…
  • 2015 American Transplant Congress

    External Validation of Clinical Prediction Models of Patient and Graft Survival in a Canadian Cohort of Kidney Transplant Recipients

    S. Singh,1,2 D. Naimark,1,2,3 J. Victor,2 J. Kim.1,2,4,5

    1Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada; 2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; 3Division of Nephrology, Sunnybrook Health Sciences Center, Toronto, ON, Canada; 4Division of Nephrology and the Kidney Transplant Program, University Health Network, Toronto, ON, Canada; 5Division of Nephrology and the Renal Transplant Program, St. Michael's Hospital, Toronto, ON, Canada.

    Background: Several clinical prediction models (CPM) of patient and graft survival in kidney transplant recipients have been developed as tools to assist physicians in identifying…
  • 2015 American Transplant Congress

    Gender Differences in Kidney Transplant Delayed Graft Function Are Independent of Donor-Recpient Size Mismatch

    M. Levine,1 A. Thomasson,1 D. Aufhauser,1 R. Redfield,2 P. Abt,1 P. Reese.3

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Surgery, University of Wisconsin, Madison, WI; 3Medicine, University of Pennsylvania, Philadelphia, PA.

    Introduction: Superior female tolerance of ischemia reperfusion injury (IRI) relative to males has been described in animal models, but little human data are available to…
  • 2015 American Transplant Congress

    A Relative Survival Model to Compare the Risk of Mortality in Patients Awaiting Kidney Transplantation Versus Already Transplanted Patients

    M. Lorent,1,2 K. Trébern-Launay,2,1 C. Legendre,4 H. Kreis,4 G. Mourad,5 V. Garrigue,5 L. Rostaing,6 N. Kamar,6 M. Kessler,7 M. Ladrière,7 E. Morelon,8 F. Buron,8 M. Giral,2,3 Y. Foucher.1,2

    1EA 4275 - SPHERE bioStatistics, Pharmacoepidemiology and Human Sciences Research, Nantes University, Nantes, France; 2Institut de Transplantation, Urologie, Néphrologie (ITUN), Inserm U1064, CHU de Nantes, Nantes, France; 3CIC Biotherapy, CHU Nantes, Nantes, France; 4Service de Transplantation Rénale et de Soins Intensifs, Hôpital Necker, APHP Paris, Paris, France; 5Service de Néphrologie-Transplantation, Hôpital Lapeyronie, Montpellier, France; 6Service de Néphrologie, HTA, Dialyse et Transplantation d'Organes, CHU Rangueil, Toulouse, France; 7Service de Transplantation Rénale, CHU Brabois, Nancy, France; 8Service de Néphrologie, Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, Lyon, France.

    Introduction: It would be useful for physicians in some specific cases to identify whom patients could not benefit of kidney transplantations.Patients and method: To answer…
  • 2015 American Transplant Congress

    Kidney Allocation Tool of the Future: The Estimated Post-Transplant Survival (EPTS) Score

    M. Moss, M. Gillespie, T. Sparkes, B. Ravichandran, R. Ugarte, A. Haririan.

    University of Maryland, Baltimore.

    Background:Beginning December 2014, a new kidney transplant allocation system will be used. A component of this system is the Estimated Post-Transplant Survival (EPTS) score, which…
  • 2015 American Transplant Congress

    Predicting Obstructive Coronary Artery Disease in Asymptomatic Renal Patients Undergoing Renal Transplantation

    D.-A. Moutzouris, C. Baker, A. Malaweera, M. Willicombe, R. Corbett, N. Duncan, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Almost 50% of asymptomatic patients with End Stage Renal Disease (ESRD) are reported to have significant flow-limiting coronary artery disease (CAD). Our practice involves a…
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