Articles tagged "Prediction models"

2015 American Transplant Congress
Multicenter Study to Develop a Novel Prediction Index for Hepatocellular Carcinoma (HCC) Recurrence After Liver Transplant (LT)
N. Mehta,¹ J. Heimbach,² D. Harnois,³ J. Dodge,¹ J. Burns,³ D. Lee,³ W. Sanchez,² J. Roberts,¹ F. Yao.¹
¹UCSF, San Francisco, CA; ²Mayo Clinic, Rochester, MN; ³Mayo Clinic, Jacksonville, FL.
Several factors have been associated with a high risk of recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT), but no reliable risk score has…
2015 American Transplant Congress
External Validation of Clinical Prediction Models of Patient and Graft Survival in a Canadian Cohort of Kidney Transplant Recipients
S. Singh,^1,2 D. Naimark,^1,2,3 J. Victor,² J. Kim.^1,2,4,5
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; ³Division of Nephrology, Sunnybrook Health Sciences Center, Toronto, ON, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, University Health Network, Toronto, ON, Canada; ⁵Division of Nephrology and the Renal Transplant Program, St. Michael's Hospital, Toronto, ON, Canada.
Background: Several clinical prediction models (CPM) of patient and graft survival in kidney transplant recipients have been developed as tools to assist physicians in identifying…
2015 American Transplant Congress
Gender Differences in Kidney Transplant Delayed Graft Function Are Independent of Donor-Recpient Size Mismatch
M. Levine,¹ A. Thomasson,¹ D. Aufhauser,¹ R. Redfield,² P. Abt,¹ P. Reese.³
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Surgery, University of Wisconsin, Madison, WI; ³Medicine, University of Pennsylvania, Philadelphia, PA.
Introduction: Superior female tolerance of ischemia reperfusion injury (IRI) relative to males has been described in animal models, but little human data are available to…
2015 American Transplant Congress
A Relative Survival Model to Compare the Risk of Mortality in Patients Awaiting Kidney Transplantation Versus Already Transplanted Patients
M. Lorent,^1,2 K. Trébern-Launay,^2,1 C. Legendre,⁴ H. Kreis,⁴ G. Mourad,⁵ V. Garrigue,⁵ L. Rostaing,⁶ N. Kamar,⁶ M. Kessler,⁷ M. Ladrière,⁷ E. Morelon,⁸ F. Buron,⁸ M. Giral,^2,3 Y. Foucher.^1,2
¹EA 4275 - SPHERE bioStatistics, Pharmacoepidemiology and Human Sciences Research, Nantes University, Nantes, France; ²Institut de Transplantation, Urologie, Néphrologie (ITUN), Inserm U1064, CHU de Nantes, Nantes, France; ³CIC Biotherapy, CHU Nantes, Nantes, France; ⁴Service de Transplantation Rénale et de Soins Intensifs, Hôpital Necker, APHP Paris, Paris, France; ⁵Service de Néphrologie-Transplantation, Hôpital Lapeyronie, Montpellier, France; ⁶Service de Néphrologie, HTA, Dialyse et Transplantation d'Organes, CHU Rangueil, Toulouse, France; ⁷Service de Transplantation Rénale, CHU Brabois, Nancy, France; ⁸Service de Néphrologie, Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, Lyon, France.
Introduction: It would be useful for physicians in some specific cases to identify whom patients could not benefit of kidney transplantations.Patients and method: To answer…
2015 American Transplant Congress
Kidney Allocation Tool of the Future: The Estimated Post-Transplant Survival (EPTS) Score
M. Moss, M. Gillespie, T. Sparkes, B. Ravichandran, R. Ugarte, A. Haririan.
University of Maryland, Baltimore.
Background:Beginning December 2014, a new kidney transplant allocation system will be used. A component of this system is the Estimated Post-Transplant Survival (EPTS) score, which…
2015 American Transplant Congress
Predicting Obstructive Coronary Artery Disease in Asymptomatic Renal Patients Undergoing Renal Transplantation
D.-A. Moutzouris, C. Baker, A. Malaweera, M. Willicombe, R. Corbett, N. Duncan, J. Galliford, A. McLean, D. Taube.
Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Almost 50% of asymptomatic patients with End Stage Renal Disease (ESRD) are reported to have significant flow-limiting coronary artery disease (CAD). Our practice involves a…
2015 American Transplant Congress
Hospital Characteristics Mediate Variation in Cirrhosis Mortality in Transplant and Non-Transplant Facilities
A. Mathur,¹ A. Chakrabarti,² K. Sheetz,² J. Mellinger,³ M. Volk,³ N. Katariya,¹ A. Singer,¹ W. Hewitt,¹ K. Reddy,¹ A. Moss.¹
¹Surgery, Mayo Clinic Arizona, Phoenix, AZ; ²Surgery, University of Michigan, Ann Arbor, MI; ³Medicine, University of Michigan, Ann Arbor, MI.
Hospitals vary significantly in cirrhosis mortality. We aimed to determine whether hospital structural characteristics mediate this effect.Methods: We used 2009 data from the HCUP Nationwide…
2015 American Transplant Congress
Altered Intestinal Microbiome as a Potential Biomarker for Failed Immune-Regulation in Autoimmune Type 1 Diabetes Mellitus
P. Chhabra,¹ A. Spano,² D. Bowers,¹ M. Wu,² L. Langman,¹ M. Timko,² K. Brayman.¹
¹Department of Surgery, University of Virginia, Charlottesville, VA; ²Department of Biology, University of Virginia, Charlottesville, VA.
Purpose: Beta-cell destruction results due to a failure of immune-regulation in type 1 diabetes (T1D). We investigated alterations in the intestinal microbiome composition as a…
2015 American Transplant Congress
Association Between the Timed Up and Go Test and Waitlisting for Kidney Transplantation
M. Chiles,¹ K. Foley,¹ R. Crew,¹ G. Dube,¹ H. Morris,¹ S. Patel,² J. Camacho,² D. Cohen,¹ L. Ratner,² S. Mohan.¹
¹Department of Medicine, Columbia University College of Physicians & Surgeons, New York, NY; ²Department of Surgery, Columbia University College of Physicians & Surgeons, New York, NY.
Introduction: The Timed Up and Go Test (TUGT) is a test of balance, mobility and functional capacity. Longer times on the TUGT are associated with…
2015 American Transplant Congress
The Donor Risk Index Does Not Accurately Classify Patients With or Without Graft Failure
E. Franco,¹ T. Athanasios,² N. Kemmer,³ L. Leone,¹ A. Alsina,¹ B. Djulbegovic.²
¹Surgery, TGMG/USF Morsani College of Medicine, Tampa, FL; ²Internal Medicine, Morsani College of Medicine, USF, Morsani College of Medicine, Tampa, FL; ³Hepatology, TGMG/USF Morsani College of Medicine, Tampa, FL.
In liver transplantation assessing risk of donor is paramount to graft survival. The donor risk index (DRI) was introduced as a predictor of graft failure…