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Articles tagged "Prediction models"

  • 2016 American Transplant Congress

    Probability of Transplant (POT) Index: A Novel Method to Predict the Likelihood of an Adult Liver Transplant.

    J. Moffett,1 M. Kueht,1 H. Petrowsky,2 I. Riaz,3 C. Nalty,4 S. Khaderi,1 C. O'Mahony,1 J. Goss,1 A. Rana.1

    1Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX; 2Department of Visceral and Transplant Surgery, University Hospital of Zurich, Zurich, Switzerland; 3Department of Internal Medicine, University of Arizona, Tucson, AZ; 4Department of Epidemiology and Biostatistics, Texas A&M Health Sciences Center, College Station, TX.

    Background: Access to liver transplantation is limited by a multitude of factors, which are quite variable among transplant candidates, and is underscored by the shortage…
  • 2016 American Transplant Congress

    A Call for a New Paradigm of Organ Allocation within the Confines of MELD for Those Who Are Not “the Sickest”.

    T. Baker, A. Siarris, P. Accoh, D. Ladner.

    Comprehensive Transplant Center, Northwestern University, Chicago, IL.

    BACKGROUND: Liver Allocation policy in the United States is in dynamic flux, with revisions in policy reflecting designs to optimize access to and outcomes for…
  • 2016 American Transplant Congress

    Characteristics and Outcome of Patients Placed on Extracorporeal Membrane Oxygenation as Bridge to Lung Transplantation.

    E. Batchelor, J. Bland, D. Douglass, J. Mullins, M. Mohanka, S. Bollineni, V. Kaza, M. Wait, F. Torres, A. Banga.

    University of Texas Southwestern Medical Center, Dallas, TX.

    BackgroundExtracorporeal membrane oxygenation (ECMO) is increasingly utilized as bridge to lung transplantation (LT), with studies reporting one-year survival of 50-90%. Lower than expected survival has…
  • 2016 American Transplant Congress

    Understanding the Dynamics of a Suddenly Plateauing Kidney Waiting List.

    A. Wilk, D. Stewart, E. Edwards.

    United Network for Organ Sharing, Richmond, VA.

    Background: The number of candidates on the kidney (KI) wait list (WL) abruptly flattened around the time the new Kidney Allocation System (KAS) was implemented…
  • 2016 American Transplant Congress

    Deceased Donor ABO-Incompatible Kidney Transplantation Has the Potential to Reduce Blood Group Disparity.

    M. Manook,1 L. Bradbury,2 D. Osei-Bordom,1 B. Sandhu,1 T. Maggs,1 O. Shaw,1 N. Kessaris,1 S. Shah,3 A. Dorling, N. Mamode.1

    1Guy's & St Thomas' Hospital, London, United Kingdom; 2NHS Blood & Transplant, Bristol, United Kingdom; 3King's College Hospital, London, United Kingdom.

    Introduction: Patients with blood group O or B wait significantly longer for a kidney transplant than other groups. Blood group incompatible transplantation is widely accepted…
  • 2015 American Transplant Congress

    Hospital Characteristics Mediate Variation in Cirrhosis Mortality in Transplant and Non-Transplant Facilities

    A. Mathur,1 A. Chakrabarti,2 K. Sheetz,2 J. Mellinger,3 M. Volk,3 N. Katariya,1 A. Singer,1 W. Hewitt,1 K. Reddy,1 A. Moss.1

    1Surgery, Mayo Clinic Arizona, Phoenix, AZ; 2Surgery, University of Michigan, Ann Arbor, MI; 3Medicine, University of Michigan, Ann Arbor, MI.

    Hospitals vary significantly in cirrhosis mortality. We aimed to determine whether hospital structural characteristics mediate this effect.Methods: We used 2009 data from the HCUP Nationwide…
  • 2015 American Transplant Congress

    Altered Intestinal Microbiome as a Potential Biomarker for Failed Immune-Regulation in Autoimmune Type 1 Diabetes Mellitus

    P. Chhabra,1 A. Spano,2 D. Bowers,1 M. Wu,2 L. Langman,1 M. Timko,2 K. Brayman.1

    1Department of Surgery, University of Virginia, Charlottesville, VA; 2Department of Biology, University of Virginia, Charlottesville, VA.

    Purpose: Beta-cell destruction results due to a failure of immune-regulation in type 1 diabetes (T1D). We investigated alterations in the intestinal microbiome composition as a…
  • 2015 American Transplant Congress

    Association Between the Timed Up and Go Test and Waitlisting for Kidney Transplantation

    M. Chiles,1 K. Foley,1 R. Crew,1 G. Dube,1 H. Morris,1 S. Patel,2 J. Camacho,2 D. Cohen,1 L. Ratner,2 S. Mohan.1

    1Department of Medicine, Columbia University College of Physicians & Surgeons, New York, NY; 2Department of Surgery, Columbia University College of Physicians & Surgeons, New York, NY.

    Introduction: The Timed Up and Go Test (TUGT) is a test of balance, mobility and functional capacity. Longer times on the TUGT are associated with…
  • 2015 American Transplant Congress

    The Donor Risk Index Does Not Accurately Classify Patients With or Without Graft Failure

    E. Franco,1 T. Athanasios,2 N. Kemmer,3 L. Leone,1 A. Alsina,1 B. Djulbegovic.2

    1Surgery, TGMG/USF Morsani College of Medicine, Tampa, FL; 2Internal Medicine, Morsani College of Medicine, USF, Morsani College of Medicine, Tampa, FL; 3Hepatology, TGMG/USF Morsani College of Medicine, Tampa, FL.

    In liver transplantation assessing risk of donor is paramount to graft survival. The donor risk index (DRI) was introduced as a predictor of graft failure…
  • 2015 American Transplant Congress

    Phenotypic Personalized Medicine: Mechanism-Independent Convergence Into Target Serum Tacrolimus Levels for Optimized Liver Transplant Immunosuppression

    A. Zarrinpar,1 A. Silva,2 D.-K. Lee,3 N. Datta,1 C.-M. Ho,2 D. Ho.3

    1Surgery-Division of Liver and Pancreas Transplantation, UCLA, Los Angeles, CA; 2Mechanical Engineering, UCLA, Los Angeles, CA; 3Bioengineering, and Oral Biology and Medicine, UCLA, Los Angeles, CA.

    PURPOSE:Immunosuppressive drugs such as tacrolimus have narrow therapeutic ranges and their dosing variability necessitates intensive drug monitoring. This study aimed to use Feedback System Control…
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