Articles tagged "Prediction models"

2017 American Transplant Congress
A Multidimensional Prognostic Score and Nomogram to Predict Kidney Transplant Survival: The Integrative Box (iBox) System.
A. Loupy,¹ O. Aubert,¹ B. Orandi,² A. Jackson,² M. Naesens,³ N. Kamar,¹ O. Thaunat,¹ E. Morelon,¹ M. Delahousse,¹ D. Viglietti,¹ D. Glotz,¹ C. Legendre,¹ X. Jouven,¹ R. Montgomery,² M. Stegall,⁴ D. Segev,² C. Lefaucheur.¹
¹Paris Translational Research Center for Organ Transplantation, Paris, France; ²Johns-Hopkins, Baltimore; ³Leuven University, Leuven, Belgium; ⁴Mayo Clinic, Rochester
The transplant field currently lacks of robust risk stratification models leading to major problems for clinical care, clinical trials, and medical progress. The goal of…
2017 American Transplant Congress
Improved Outcome of Kidney Transplants by Donor Recipient Matching Based on Predicted Indirectly Recognizable HLA Epitopes.
O. Staeck,¹ M. Niemann,⁴ F. Halleck,¹ D. Khadzhynov,¹ C. Schönemann,² P. Reinke,¹ E. Spierings,³ K. Budde,¹ N. Lachmann.²
¹Nephrology, Charité Universitaetsmedizin, Berlin, Germany; ²HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; ³Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands; ⁴PIRCHE, Berlin, Germany
Introduction: De novo donor-specific HLA antibodies (dnDSA) are recognized as a risk factor for graft loss. Determinants of DSA specificity are generated via the indirect…
2017 American Transplant Congress
Predicting Recurrence Prior to Transplant: The Response of HCC to Chemoembolization.
T. Sandow,¹ H. Bohorquez,² D. Kirsch,¹ P. Thevenot,³ K. Nunez,³ A. Albar,¹ D. DeVun,¹ J. Gimenez,¹ G. Galliano,⁴ A. Cohen,² G. Loss,² D. Kay,¹ P. Gulotta.¹
¹Radiology, Ochsner Clinic Foundation, New Orleans, LA; ²Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; ³Institute of Translational Research, Ochsner Clinic Foundation, New Orleans, LA; ⁴Pathology, Ochsner Clinic Foundation, New Orleans, LA
Purpose:This study assesses imaging response characteristics of patients with hepatocellular carcinoma (HCC) to chemoembolization (TACE) as a bridge to transplant and the risk of post-transplant…
2017 American Transplant Congress
The Incidence, Mortality and Prediction Model for Fractures After Kidney Transplantation in the United States.
X. Liu, S. Bae, M. McAdams DeMarco, D. Segev.
JHU, Baltimore, MD
Kidney transplant (KT) recipients are more likely than general population to have fractures. In the general population, fractures are associated with morbidity, mortality, and high…
2017 American Transplant Congress
Molecular Classifier of Antibody-Mediated Rejection Is a Better Predictor of Histologic Rejection Than a Corresponding Transcript Set and Is Further Improved When Combined with Classifiers of Rejection Syndromes.
K. Famulski, P. Halloran.
University of Alberta, Edmonton, AB, Canada
Molecular and histologic changes in graft rejection are not completely specific, often being induced by injuries and other diseases. We examined various methods for using…
2017 American Transplant Congress
The Performance of Four Tools for the Prediction of Potential for Organ Donation After Cardiac Death in Neurocritical Patients: A Prospective, Multicenter, Observational Study.
Z. Guo,¹ G. Xu,¹ P. Schroder,² M. Manyalich,³ X. He,¹ G. Chen.¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; ²Department of Surgery, Duke University Medical Center, Durham; ³Transplant Procurement Management-Donation & Transplantation institute Foundation, Barcelona, Spain
Background Successful donation after circulatory death (DCD) requires identification of patients dieing within limited time after withdrawal of life-sustaining treatment (WLST). We aimed to compare…
2017 American Transplant Congress
Prediction of Evolution Toward Brain Death in Acute Neurocritical Patients Identified as Potential Organ Donors.
G. Xu, P. Xu, Z. Guo, X. He.
Department of Neurosurgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, Ecuador; Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
Objective: Reliable prediction of brain death (BD) is of specific interest for organ donation after brain death(DBD). We sought to establish a score based on…
2017 American Transplant Congress
Decision Tree Analysis of Renal Transplantation Recipients Outcomes: A Single Center Data Mining in the Big Data Era.
J. Zhou,¹ Y. Shen,² R. Wang,¹ H. Huang,¹ J. Wu,¹ J. Chen.¹
¹Kidney Disease Center, the First Affiliated Hospital, Zhejiang University, Hangzhou, China; ²Department of Epidemiology, College of Medicine, Zhejiang University, Hangzhou, China
Background This is the era of big data and it may help manage clinical practice better. Decision tree analysis is a useful data mining tool…
2017 American Transplant Congress
Insulin Therapy in Pancreas Donors as a Predictor of Subsequent Transplant Outcome.
I. Shapey,¹ H. Khambalia,² A. Summers,² T. Augustine,² M. Rutter,¹ D. van Dellen.¹
¹Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; ²Department of Renal and Pancreas Transplantation, Central Manchester University Hospitals, Manchester, United Kingdom
Introduction: Brain stem death causes high levels of systemic catecholamines and inflammation affecting all organs. These changes, and the routine use of high-dose corticosteroids in…
2017 American Transplant Congress
The Association of Donor Vasoactive Drugs with Pancreas Transplant Graft Survival.
I. Shapey,¹ P. Yianoullou,² A. Summers,² T. Augustine,² M. Rutter,¹ D. van Dellen.²
¹Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; ²Department of Renal and Pancreas Transplantation, Central Manchester University Hospitals, Manchester, United Kingdom
Introduction: Vasoactive drugs (VaD) are commonly used to correct abnormal haemodynamics of organ donors in Intensive Care Units (ICU). VaDs can differentially affect insulin secretion…