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Articles tagged "Post-transplant lymphoproliferative disorder (PTLD)"

  • 2017 American Transplant Congress

    Presence of Anellovirus Nucleic Acid Sequences in Involved Tissue Is Associated with Worse Patient Survival in Post-Transplant Lymphoproliferative Disorder.

    V. Dharnidharka, R. Chen, M. Ruzinova, P. Parameswaran, H. O'Gorman, K. Wylie, G. Storch.

    Washington University in St Louis School of Medicine, St. Louis

    Introduction: PTLD remain a feared complication of organ and tissue transplant, with high morbidity and mortality. While 50-80% of cases are strongly associated with Epstein-Barr…
  • 2016 American Transplant Congress

    Chronic High Epstein-Barr Viral Load Carriage in Pediatric Kidney Transplant Recipients.

    M. Yamada,1 P. Fadaker,1 C. Nguyen,1 A. Ganoza,2 A. Humar,2 M. Michaels,1,2 M. Green.1,2

    1Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA; 2Surgery, University of Pittsburgh, Pittsburgh, PA.

    BackgroundThe development of Epstein-Barr virus (EBV) infection and post-transplant lymphoproliferative disorder (PTLD) is normally associated with a high EBV viral load in peripheral blood. Observations…
  • 2016 American Transplant Congress

    Rare Presentation of PTLD as Parotitis.

    R. Pullalarevu, A. Posadas Salas, G. Mour, T. Srinivas, N. Salazar, P. Mohan.

    Medicine, MUSC, Charleston, SC.

    28y/o AAF w/ hx of CAH, HTN, and ESRD, was on HD for 3 yrs. Pt was EBV seronegative prior to transplant (tx). She received…
  • 2016 American Transplant Congress

    Incidence of Post-Transplant Lymphoproliferative Disorder in First, Kidney-Only Transplant Recipients Remains Stable.

    J. Molony,1 Y. Peng,1 N. Baker,2 U. Meier-Kriesche,3 J. Snyder.1

    1Chronic Disease Research Group, Minneapolis; 2Brystol-Myers Squibb Company (BMS), Hopewell; 3BMS, Lawrenceville.

    We estimated the incidence of and risk factors for post-transplant (TX) lymphoproliferative disorder (PTLD) in the 3 years post-TX for adults with first, kidney-only TX…
  • 2016 American Transplant Congress

    Predictors of Post Transplant Lymphoprolipherative Disorder Among Adult Kidney Transplant Recipients.

    M. Mohamed, S. Parajuli, B. Muth, A. Djamali, B. Astor.

    Internal Medicine, University of Wisconsin School of Medicine, Madison, WI.

    Objective: Identifying predictors of Post Transplant Lymphoprolipherative Disorder (PTLD); early (0 - 3 years) and late in kidney transplantation.Methodology: Single center longitudinal study among kidney…
  • 2016 American Transplant Congress

    Long-Term vs Short-Term Valganciclovir Prophylaxis Use for Cytomegalovirus and Epstein-Barr Virus Infections in Pediatric Living Related Liver Transplantation.

    T. Ueno,1 H. Yamanaka,1 Y. Takama,1 N. Tanaka,1 Y. Tazuke,1 K. Bessho,2 H. Okuyama.1

    1Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Japan; 2Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan.

    [Purpose] Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections are the most important viral infections in pediatric patients with transplant. Valganciclovir (VGCV) has been used as…
  • 2016 American Transplant Congress

    De Novo Proliferative Glomerulonephritis with Monoclonal IgG Deposits of the IgG1κ Subtype in a Kidney Allograft: Protocol Biopsy Findings.

    T. Tsuji,1 M. Miura,2 M. Yanai,1 H. Itami,1 Y. Ishii,1 M. Akimoto,1 Y. Fukasawa.1

    1Department of Pathology, Sapporo City General Hospital, Sapporo, Japan; 2Departments of Renal Transplant Surgery and Urology, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Proliferative glomerulonephritis with monoclonal immunoglobulin G (IgG) deposits (PGNMID) has recently been described in cases with glomerular disease. Only a dozen cases of recurrent or…
  • 2016 American Transplant Congress

    Targeting the Constitutively Active PI3K/Akt/mTOR Signaling Pathway in Epstein-Barr Virus B Cell Lymphomas.

    A. Sang, G. Ivison, C. Esquivel, S. Krams, O. Martinez.

    Division of Abdominal Transplantation, Stanford School of Medicine, Stanford, CA.

    Epstein-Barr virus (EBV) B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD) is a major problem in organ transplantation. Reduction of immunosuppression sometimes result in tumor…
  • 2016 American Transplant Congress

    Banked EBV-Specific T-Cells for Treatment of Rituximab Refractory EBV+ B-Cell Lymphoma in Solid Organ Transplantation Recipients.

    S. Prockop,1 E. Doubrovina,1 C. Sauter,2 S. Suser,1 R. O'Reilly.1

    1MKSCC, New York, NY; 2MSKCC, New York, NY.

    Morbidity and mortality from EBV-induced post-transplant lymphoproliferative disease (EBV+ PTLD) can complicate solid organ transplant (SOT), particularly in those seronegative prior to transplant and in…
  • 2015 American Transplant Congress

    Preemptive Rituximab Therapy of Epstein-Barr Virus (EBV) Infection to Prevent Post-Transplant Lymphoproliferative Disease (PTLD) After Pediatric Solid Organ Transplantation (SOT)

    Y. Ahn,1 N.-J. Yi,2 S. Min,2 I.-S. Ha,1 H. Cheong,1 H. Kang.1

    1Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea; 2Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

    Purpose: More than 90% of pediatric PTLD after solid organ transplantation is associated with EBV infection. Reduction in immunosuppression is the first step to prevent…
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