Articles tagged "Polymerase chain reaction (PCR)"

2017 American Transplant Congress
Impact of Peri-Transplant Viral Upper Respiratory Infection on Pediatric Liver Transplant Outcomes.
J. Kohler,¹ T. Miloh,¹ K. Hosek,¹ J. Goss,² F. Munoz.¹
¹Pediatrics, Baylor College of Medicine, Houston, TX; ²Surgery, Texas Children's Hospital, Houston, TX
BACKGROUND: Viral upper respiratory infection (vURI) is common in children and its effect at the time of liver transplant (LT) on the post-operative outcomes is…
2017 American Transplant Congress
Calibration of BK Virus Nucleic Acid Amplification Testing to the 1^st WHO International Standard for BK Virus.
S. Tan,¹ S. Milligan,² M. Sahoo,³ N. Taylor,² B. Pinsky.^1,2,3
¹Department of Medicine, Division of Infectious Diseases, Stanford University School of Medicine, Stanford, CA; ²Clinical Virology Laboratory, Stanford Health Care, Stanford, CA; ³Department of Pathology, Stanford University School of Medicine, Stanford, CA
Significant inter-assay variability in the quantification of BK virus (BKV) DNA has limited the broad applicability of thresholds for the management of BKV infection in…
2016 American Transplant Congress
Developing a PCR-Based System to Access the Correlation of Local Chimerism and Fate of the Vascularized Composite Allotransplant.
X.-T. Huang,¹ H.-Y. Cheng,¹ C.-F. Lin,¹ S.-S. Qiu,² L.-Y. Shih,¹ F.-C. Wei.^1,2,3
¹Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; ²Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; ³College of Medicine, Chang Gung University, Gueishan, Taoyuan, Taiwan.
It is established that development of mixed chimerism following allotransplantation is associated with induction of tolerance to allotransplants. Although chimerism in peripheral blood can be…
2016 American Transplant Congress
The Epidemiology of Clostridium difficile Infection in a National Kidney Transplant Center.
C. Kennedy,¹ C. Waldron,¹ M. Scally,² K. Burns,² C. Magee,¹ F. Fitzpatrick.²
¹Department of Nephrology, Beaumont Hospital, Dublin, Ireland; ²Department of Microbiology, Beaumont Hospital, Dublin, Ireland.
BackgroundKidney transplant recipients (KTRs) are at increased risk of Clostridium difficile infection (CDI). We aimed to retrospectively describe the epidemiology of CDI in a national…
2016 American Transplant Congress
Development of a Vascularized Thymus-Sternum Composite Tissue Allograft Model in Non-Human Primates.
N. O'Neill, S. Sendil, Y. Zhao, A. Hershfield, I. Tatarov, G. Braileanu, W. Hassanein, D. Parsell, A. Azimzadeh, L. Burdorf, R. Pierson, A. Nam.
Surgery, University of Maryland, Baltimore, MD.
Purpose: Vascularized composite allotransplantation (VCA) has demonstrated clinical success with standard immunosuppressive strategies in face, hand, and forearm transplantations. We developed a non-human primate model…
2016 American Transplant Congress
Viral Gastroenteritis in Adult and Pediatric Solid Organ Transplant (SOT) Patients.
C. Hernández Garcia,¹ B. Lee,¹ X. Pang,² H. Yuan Zhou,¹ J. Preikisatis.¹
¹Medicine, University of Alberta, Edmonton, AB, Canada; ²Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
BACKGROUND. Diarrhea in SOT recipients is common and often attributed to immunosuppressive drug side effects. However, enteric viruses are important causes of acute gastroenteritis and…
2015 American Transplant Congress
Small RNA Sequencing-Enabled Discovery of Circulating Extracellular MicroRNAs as Noninvasive Biomarkers of Liver Allograft Status
H. Yang,¹ T. Muthukumar,¹ K. Akat,² D. Briskin,² T. Tuschl,² M. Suthanthiran.¹
¹Weill Cornell Medical Center, New York; ²Rockefeller University, New York.
MicroRNAs are ideal candidates as blood-based biomarkers. Comprehensive profiling of microRNAs is challenging. We overcame the existing challenges by developing robust protocols for isolation of…
2015 American Transplant Congress
Evaluation of the Gastrointestinal Tract as a Potential Route of Primary Polyomavirus Infection
G. Huang,¹ G. Zeng,² Y. Huang,² P. Randhawa.²
¹Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Detection of Polyomavirus(Py) DNA in metropolitan river water worldwide has led to the suggestion that primary viral infection can occur by the oral route. The…