ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Polymerase chain reaction (PCR)"

  • 2017 American Transplant Congress

    MicroRNAs and Long Non-Coding RNAs as Potential Novel Biomarkers in Transplanted Patients with Candida Infection.

    A. Yang,1 C. Zhou,2 D. Li,3 W. Ju,1 Z. Guo,1 L. Wu,1 A. Hu,1 Y. Ma,1 D. Wang,1 X. Zhu,1 X. He.1

    1Organ Transplantation Center, The First Affiliated Hospital of Sun Yat -sen University, Guangzhou, Guangdong, China; 2Gastroenterology Unit, Massachusetts General Hospital, Boston, MA; 3Ophthalmology, Schepens Research Institute, Boston, MA

    There is an urgent need to develop sensitive and specific biomarkers for the early diagnosis of candida infection in transplanted patients. miRNAs and lncRNAs are…
  • 2017 American Transplant Congress

    NFAT-Regulated Cytokine Gene Expression for Immune Monitoring in Kidney Transplant Recipients – A Randomized Controlled Trial.

    A. Webber,1 V. Tatapudi,2 C. Leung,3 F. Vincenti.1,3

    1Division of Nephrology, UCSF, San Francisco, CA; 2Division of Nephrology, NYUMC, New York, NY; 3Surgery, UCSF, San Francisco, CA

    Purpose: To demonstrate that a pharmacodynamics assay using Real Time (RT)-PCR to measure residual expression (RE) of nuclear factor of activated T cell (NFAT)-dependent cytokines…
  • 2016 American Transplant Congress

    Development of a Vascularized Thymus-Sternum Composite Tissue Allograft Model in Non-Human Primates.

    N. O'Neill, S. Sendil, Y. Zhao, A. Hershfield, I. Tatarov, G. Braileanu, W. Hassanein, D. Parsell, A. Azimzadeh, L. Burdorf, R. Pierson, A. Nam.

    Surgery, University of Maryland, Baltimore, MD.

    Purpose: Vascularized composite allotransplantation (VCA) has demonstrated clinical success with standard immunosuppressive strategies in face, hand, and forearm transplantations. We developed a non-human primate model…
  • 2016 American Transplant Congress

    Viral Gastroenteritis in Adult and Pediatric Solid Organ Transplant (SOT) Patients.

    C. Hernández Garcia,1 B. Lee,1 X. Pang,2 H. Yuan Zhou,1 J. Preikisatis.1

    1Medicine, University of Alberta, Edmonton, AB, Canada; 2Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.

    BACKGROUND. Diarrhea in SOT recipients is common and often attributed to immunosuppressive drug side effects. However, enteric viruses are important causes of acute gastroenteritis and…
  • 2016 American Transplant Congress

    Developing a PCR-Based System to Access the Correlation of Local Chimerism and Fate of the Vascularized Composite Allotransplant.

    X.-T. Huang,1 H.-Y. Cheng,1 C.-F. Lin,1 S.-S. Qiu,2 L.-Y. Shih,1 F.-C. Wei.1,2,3

    1Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; 2Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; 3College of Medicine, Chang Gung University, Gueishan, Taoyuan, Taiwan.

    It is established that development of mixed chimerism following allotransplantation is associated with induction of tolerance to allotransplants. Although chimerism in peripheral blood can be…
  • 2016 American Transplant Congress

    The Epidemiology of Clostridium difficile Infection in a National Kidney Transplant Center.

    C. Kennedy,1 C. Waldron,1 M. Scally,2 K. Burns,2 C. Magee,1 F. Fitzpatrick.2

    1Department of Nephrology, Beaumont Hospital, Dublin, Ireland; 2Department of Microbiology, Beaumont Hospital, Dublin, Ireland.

    BackgroundKidney transplant recipients (KTRs) are at increased risk of Clostridium difficile infection (CDI). We aimed to retrospectively describe the epidemiology of CDI in a national…
  • 2015 American Transplant Congress

    Small RNA Sequencing-Enabled Discovery of Circulating Extracellular MicroRNAs as Noninvasive Biomarkers of Liver Allograft Status

    H. Yang,1 T. Muthukumar,1 K. Akat,2 D. Briskin,2 T. Tuschl,2 M. Suthanthiran.1

    1Weill Cornell Medical Center, New York; 2Rockefeller University, New York.

    MicroRNAs are ideal candidates as blood-based biomarkers. Comprehensive profiling of microRNAs is challenging. We overcame the existing challenges by developing robust protocols for isolation of…
  • 2015 American Transplant Congress

    Evaluation of the Gastrointestinal Tract as a Potential Route of Primary Polyomavirus Infection

    G. Huang,1 G. Zeng,2 Y. Huang,2 P. Randhawa.2

    1Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; 2Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Detection of Polyomavirus(Py) DNA in metropolitan river water worldwide has led to the suggestion that primary viral infection can occur by the oral route. The…
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