- 2019 American Transplant Congress - BK Virus Infection Disparity between Black and Other Races; Do Not Blame the Mycophenolic Acid*Purpose: Disparities in kidney transplant outcomes between black recipients and others continue to exist. We sought to examine the impact of race and the differential…
- 2019 American Transplant Congress - Predictive Factors for BKV Nephropathy in Renal Transplant Recipients with BK Viruria- Renal, Oxford University Hospitals, Oxford, United Kingdom *Purpose: Polyoma infection due to BK virus remains an important cause of allograft failure following renal transplantation.Intensive monitoring of urine and serum for BK virus…
- 2019 American Transplant Congress - Genome-Wide Profiling of BK Polyomavirus Integration in Urothelial Carcinoma of Kidney Transplant Recipients Reveals a Potential Microhomology or Nonhomologous End Joining Mediated Integration Mechanism*Purpose: Chronic BK polyomavirus (BKV) infection is recognized as a potential oncogenic factor of urothelial carcinoma (UC) in renal transplant recipients. Besides, a positive correlation…
- 2019 American Transplant Congress - Incidence, Risk Factors, Outcomes and Clinical Management of BK Viremia in the Modern Era of Kidney Transplantation- Toronto General Hospital, Toronto, ON, Canada *Purpose: BK viremia is endemic among kidney transplant recipients (KTR). Previous work has not compared the incidence, risk factors, and outcomes of any vs. clinically…
- 2019 American Transplant Congress - Effects of IVIG Therapy and FcγR Polymorphisms on BK Virus Nephropathy in Kidney Transplant Recipients*Purpose: BK Virus Nephropathy (BKVN) is a major complication in kidney transplant patients. Although standard treatment for BKVN is immunosuppression reduction and/or using leflunomide, studies…
- 2019 American Transplant Congress - Tandem Mass Tags Based Liquid Chromatography/ Mass Spectrometry Analysis of Quantitative Proteomic Changes in Renal Allograft Biopsies with Polyomavirus BK Nephropathy- University of Pittsburgh, Pittsburgh, PA *Purpose: Transcriptomics analyses have not generated reliable means to distinguish T-cell mediated rejection (TCMR) from BK virus nephropathy (BKVN). Proteomics-based approaches deserve further exploration since…
- 2019 American Transplant Congress - Successful Use of Hizentra to Address BK Viremia in Pediatric Transplant Population- Pediatric Nephrology, Saint Louis University, Saint Louis, MO *Purpose: BK viremia is an important problem in the pediatric renal transplant population leading to increased risk for viral associated nephropathy in the transplant. Early…
- 2019 American Transplant Congress - Prospective BK Virus Screening in the Early Post-Kidney Transplant Period: A Single Center Experience- 1UC Med Ctr, Cincinnati, OH, 2U Cincinnati, Cincinnati, OH *Purpose: BK virus screening protocols for the early (up to post-transplant day 90) post kidney transplant (KT) period vary amongst kidney transplant centers. Most commonly,…
- 2019 American Transplant Congress - Epidemiology and Outcomes of BKV Nephropathy Management by Screening Policy in a Real-Life Setting*Purpose: To verify the frequency of BKVAN in a single center's clinical setting and evaluate the response to immunosuppressive adjustments through graft survival analysis.*Methods: Retrospective…
- 2019 American Transplant Congress - Development of De Novo Antibody in Renal Transplant Recipients with BK Viremia Managed with Immunosuppression Reduction*Purpose: To determine the development of de novodonor specific antibodies (DSA) in renal transplant recipients with immunosuppression modulation and BK viremia and the associated risk…
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