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Articles tagged "Polyma virus"

  • 2019 American Transplant Congress

    Polyomavirus Genotypes In Renal Transplant Recipients In The United States

    N. Khoury1, C. Thongprayoon2, N. Leeaphorn3, J. Bruminhent4, W. Cheungpasitporn5

    1Henry Ford Transplant Institute, Detroit, MI, 2Mayo Clinic, Rochester, MN, 3University of Missouri, Kansas, MO, 4Mahidol University, Bangkok, Thailand, 5University of Mississippi, Jackson, MS

    *Purpose: BK Polyomavirus (BKV) subtypes and subgroups present uneven geographical distribution, suggesting a potential relationship with ethnicity. In the United States where there is a…
  • 2019 American Transplant Congress

    The Complexity of T Cell-Mediated Rejection Scenarios: Identifying BK in Biopsies with TCMR

    P. F. Halloran and The INTERCOMEX Investigators1, G. Gupta2, J. Reeve3

    1University of Alberta, Edmonton AB, AB, Canada, 2Virginia Commonwealth University, Richmond, VA, 3Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada

    *Purpose: Some transplanted kidneys have concomitant T cell-mediated rejection (TCMR) and BK virus nephropathy (BK). The histologic diagnosis in BK sometimes overlooks the TCMR component,…
  • 2019 American Transplant Congress

    Cidofovir for BK Nephropathy Rescue Treatment: A Single Center Experience

    J. Slatinska1, E. Honsova2, T. Rohal1, A. Slavcev3, P. Hruba4, O. Viklicky1

    1Nephrology, IKEM, Prague, Czech Republic, 2Pathology, IKEM, Prague, Czech Republic, 3Immunology, IKEM, Prague, Czech Republic, 4Transplant Laboratory, IKEM, Prague, Czech Republic

    *Purpose: Cidofovir is a potentially nephrotoxic antiviral drug used primarily as a treatment for CMV retinitis however due to its potent antiviral effects has been…
  • 2019 American Transplant Congress

    Predictors of Response to Intravenous Immunoglobulin for Treatment of Polyoma Nephropathy

    S. Sethi, A. Vo, A. Peng, R. Najjar, K. Lim, S. Jordan, E. Huang

    Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: BK nephropathy is an important cause of allograft dysfunction or loss. IVIg is hypothesized to be effective by providing passive immunity to BK virus…
  • 2019 American Transplant Congress

    Evaluation Of BK Polyomavirus Monitoring And Management In Kidney Transplant Recipients

    M. Tomeczkowicz, S. Mondal, N. Sulejmani, B. Summers, T. Larson, A. Jantz

    Henry Ford Hospital, Detroit, MI

    *Purpose: BK polyomavirus (BKV) is an opportunistic infection that can lead to BKV nephropathy and premature graft loss within the first year post-transplant. The mainstay…
  • 2019 American Transplant Congress

    Increasing Net Immunosuppression after BK Viremia

    L. Cotiguala, A. Masood, J. Park, A. Naik

    University of Michigan, Ann Arbor, MI

    *Purpose: BK viremia is associated with inferior kidney allograft outcomes. Typical treatment involves reduction in immunosuppression. However reduction in immunosuppression is also likely to lead…
  • 2019 American Transplant Congress

    Low Specific Gravity Of First Morning Urine Predicts Bkvn in Kidney Transplant Recipients With Bk Viruria

    G. Huang1, X. Chen1, Z. Wang2, Y. Nuertai2, W. Chen3, S. Yang3, P. Chen4, C. Wang1

    1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2Department of Clinical Medicine, Sun Yat-sen University Zhongshan School of Medicine, Guangzhou, China, 3Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 4Department of Clinical Laboratory, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    *Purpose: BK Polyomavirus nephropathy (BKVN) is an important cause of dysfunction and failure of renal transplants. BKV usually infects urinary tract retrogradely. The collecting duct…
  • 2019 American Transplant Congress

    The Association Of Frailty With Risk Of Cytomegalovirus And BK Infection

    J. Norman1, A. Gupta2, A. Naik3, D. Cibrik2, S. Norman3

    1Internal Medicine, Univ of Michigan Medical Ctr, Ann Arbor, MI, 2Internal Medicine/Nephrology, Kansas University Medical Center, Kansas City, KS, 3Internal Medicine/Nephrology, Univ of Michigan Medical Ctr, Ann Arbor, MI

    *Purpose: Opportunistic infections are responsible for significant morbidity and mortality post-kidney transplant (KT). Recently, medical frailty has been recognized to increase the risk of death…
  • 2019 American Transplant Congress

    Protocol Cidofovir for Refractory Polyomavirus Associated Nephropathy in Kidney Transplant Recipients

    J. Clark, A. Haririan

    University of Maryland Medical Center, Baltimore, MD

    *Purpose: Dose-limiting nephrotoxicity has historically precluded the use of cidofovir for polyomavirus associated nephropathy (PVAN). With incidence of BK viremia in kidney transplant recipients increasing…
  • 2019 American Transplant Congress

    Evaluation of Infection and Renal Transplant Outcomes in the Hmong Population

    M. Jorgenson1, J. Descourouez1, D. Yang2, G. Leverson2, J. Smith2, R. Redfield2

    1UW Health, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, WI

    *Purpose: Literature suggests the Hmong people to be at higher risk for infection, particularly fungal. The risk of infection after transplant in the Hmong population…
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