ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Plasmapheresis"

  • 2019 American Transplant Congress

    Evaluation of the Safety and Tolerability of Clazakizumab® (Anti-IL-6 Monoclonal) as a Desensitization Agent in Highly-HLA Sensitized ESRD Patients (nct03380962)

    A. A. Vo, N. Ammerman, E. Huang, A. Peng, R. Najjar, S. Sethi, S. Williamsons, C. Myers, K. Lim, J. Choi, S. C. Jordan

    Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: Currently, there is growing interest in development of novel immune-modulatory drugs likely to improve allo-antibody reduction in transplantation. Clazakizumab (Vitaeris Inc.) is a humanized…
  • 2019 American Transplant Congress

    Quantifying Differential Infection Risks in HLA- and/or ABO- Incompatible Kidney Transplant Recipients

    R. Avery1, R. Montgomery2, J. Motter1, A. Massie1, E. Kraus1, K. Marr1, B. Lonze2, N. Alachkar1, K. Jackson1, M. Holechek1, D. Ostrander1, N. Desai1, M. Waldram1, S. Shoham1, S. Mehta1, J. Hiller1, J. Langlee1, S. Young1, D. Segev1, J. Garonzik Wang1

    1Johns Hopkins, Baltimore, MD, 2New York University, New York, NY

    *Purpose: Desensitization has enabled kidney transplantation across HLA-and/or ABO barriers and has conferred survival benefit to patients who lack compatible living donors (CLDKT). However, due…
  • 2019 American Transplant Congress

    Successful Use of Nonantigen Specific Immunoadsorption In ABO-Incompatible Desensitization and Humoral Rejection Treatment in Kidney Transplantation

    E. Montagud-Marrahi

    Servei de Nefrologia i Trasplantament Renal, Hospital Clínic de Barcelona, Barcelona, Spain

    *Purpose: : Immunoadsorption (IA) is an apheresis procedure that has been shown to be effective in the ABO incompatible living donor kidney transplantation (ABOi LDKT)…
  • 2019 American Transplant Congress

    Outcomes after Prolonged Therapeutic Plasma Exchange in Pediatric Kidney Transplant Patients with Early Recurrence of Focal Segmental Glomerular Sclerosis

    D. K. O'Conor1, P. R. Srivaths2, K. Hosek3, E. Gerzina1, A. Huynh1, A. Thorsen1, E. Brewer2, T. Galvan1

    1Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, 2Department of Pediatrics, Baylor College of Medicine, Houston, TX, 3Texas Children's Hospital, Houston, TX

    *Purpose: Focal segmental glomerular sclerosis (FSGS) is the most common cause of glomerulonephritis leading to end-stage renal disease (ESRD) in pediatric patients. FSGS recurs frequently…
  • 2019 American Transplant Congress

    Osmotic Demyelination Syndrome after Liver Transplantation- Etiology and Treatment Options

    P. Mihaylov1, D. Soma2, D. Kuruppu2, B. Ekser2, R. Mangus2, J. Fridell2, R. Snook2, C. Kubal2

    1Indiana Univ School of Medicine, Pavia University School of Medicine, Indianapolis, IN, 2Indiana Univ School of Medicine, Indianapolis, IN

    *Purpose: Orthotopic liver transplantation (OLT) is the only effective therapy for patients with end stage liver failure that increases long-term survival, but is not without…
  • 2019 American Transplant Congress

    Is Pre-transplant Plasmapheresis For Patients With Insignificant Abo Blood Type Antibody In Abo Blood Type Incompatible Kidney Transplant Necessary? – A Japanese Single Center Study.

    M. Miyazaki, A. Mitsuke, H. Higuchi, N. Fukuzawa, H. Tanaka, T. Hirano, T. Seki, H. Harada

    Urology and Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Hokkaido, Japan

    *Purpose: ABO incompatible kidney donor (ABOiKT) is still precious to fill up the extremely organ donor shortages in our country. Though plasmaphresis (PP) as desensitization…
  • 2018 American Transplant Congress

    Treatment Outcomes of FSGS Recurrence

    J. Mansur,1 D. Chang,2 G. Medeiros,1 M. Cristelli,1 L. Viana,1 S. Stopa,1 C. Felipe,1 G. Kirsztajn,1 H. Tedesco-Silva.1

    1Hospital do Rim, Universidade Federal de Sao Paulo, Sao Paulo, Brazil; 2Hospital Nacional Cayetano Heredia, Universidad Peruana Cayetano Heredia, Lima, Peru.

    Background: Recurrence of FSGS (focal segmental glomerulosclerosis) after kidney transplant occurs in 30% of adults and up to 80% of children and has impact on…
  • 2018 American Transplant Congress

    Modified Protocol for ABO-Incompatible Living Donor Liver Transplantation with Rituximab and Intravenous Immunoglobulin without Plasma Exchange

    B-.G. Na, E. Lee, S. Kim, S. Park.

    Center for Liver Cancer, National Cancer Center, Il-san Donggu, Goyang, Republic of Korea.

    Purpose: Since a variety of desensitization strategies including rituximab, intravenous immunoglobulin (IVIG), and plasma exchange (PE) have been introduced, the survival and outcomes of recipients…
  • 2018 American Transplant Congress

    modified DFPP Can Eliminate Donor-Reactive IgG Antibody with Preserving Fibrinogen before Kidney Transplantation

    D. Iwami,1 T. Matsumoto,2 K. Hotta,1 M. Ota,2 Y. Chiba,2 H. Higuchi,1 N. Shinohara.1

    1Renal and Genitourinary Surgery, Hokkaido University, Graduate School of Medicine, Sapporo, Hokkaido, Japan; 2Medical Engineering Center, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.

    BACKGROUND: Elimination of preexisting IgG antibodies against donor antigen is an important role before antibody-incompatible (i.e. ABO-incompatible and donor-specific antibody positive) kidney transplantation. Plasma exchange…
  • 2018 American Transplant Congress

    How Safe is Crossing the ABO Blood Group Barrier? A Meta-Analysis to Determine the Additive Risk of ABO-Incompatible Kidney Transplantation

    A. de Weerd, M. Betjes.

    Nephrology and Kidney Transplantation, Erasmus Medical Center, Rotterdam, Netherlands.

    Background ABO blood group-incompatible (ABOi) kidney transplantation is considered a safe procedure, with non-inferior outcomes in large cohort studies. Its contribution to living kidney transplantation…
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