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American Transplant Congress abstracts

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Articles tagged "Pediatric"

  • 2015 American Transplant Congress

    Home Dried Blood Spot Monitoring; a New Tool for Measuring Variability in Tacrolimus Blood Levels Over Time

    A. Al-Uzri, K. Freeman, K. Clark, L. Bleyle, S. Iragorri, R. Jenkins, D. Rozansky, D. Koop.

    Oregon Health & Science University, Portland, OR.

    PURPOSE: The measurement of variability in Tacrolimus (TAC) blood trough levels has been proposed to reflect the consistency with medication intake and adherence. A standard…
  • 2015 American Transplant Congress

    Liver Transplantation for Children With Autoimmune Hepatitis and Primary Sclerosing Cholangitis: An Analysis of the UNOS Database

    J. Jossen,1 R. Annunziato,2 J. Chu,1 H.-S. Kim,2 S. Sheflin,1 J. Lai,1 R. Arnon.1

    1Department of Pediatrics, Mount Sinai Medical Center, New York, NY; 2Fordham University, New York.

    Autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC) are progressive immune-mediated inflammatory diseases that may require liver transplant (LT). Outcomes in children undergoing LT for…
  • 2015 American Transplant Congress

    Pediatric Living Donor Liver Transplantation at KFSH&RC – Implementation of the Laparoscopic Retrieval in a High Volume Center

    M. Boehnert, M. Shagrani, T. Al Goufi, D. Broering.

    Organ Transplant Centre, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.

    Since the first successful pediatric liver transplantation was performed in 1967 the survival rate increased from 30 % to currently above 90 %. This is…
  • 2015 American Transplant Congress

    The Utility of Non-Invasive Intra Abdominal Pressure Monitoring After Pediatric Abdominal Organ Transplantation

    E. Harkin,1 M. McLeod,1 K. Khan,2 A. Natarajan.3

    1Pediatrics, Georgetown University School of Medicine, Washington, DC; 2Georgetown Transplant Institute, MedStar-Georgetown University Hospital, Washington, DC; 3Pediatrics, Pharmacology and Physiology, MedStar-Georgetown University Hospital, Washington, DC.

    Intra abdominal pressure (IAP) is monitored in critically ill children because intra-abdominal hypertension (IAH) may be associated with renal dysfunction and adverse outcomes.We retrospectively examined…
  • 2015 American Transplant Congress

    Preliminary Results of a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab in a Pediatric Patient Population Undergoing Kidney Transplantation

    D. Halleran,1 S. Schurman, T. Welch, V. Whittaker.

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Pediatric Nephrology, State University New York Upstate Medical University, Syracuse, NY.

    Purpose: We report the outcomes from single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative day…
  • 2015 American Transplant Congress

    Interventional Treatment With Minimal Surgery Is an Effective Way for Acute Portal Vein Thrombosis After Pediatric Liver Transplantation: The Experience of Largest Pediatric Liver Transplantation Center in China

    Y. Liu,1 T. Lu,1 C. Shen,1 Q. Xia,1 Y. Luo,1 T. Zhou,1 B. Qiu,1 M. Zhang,1 L. Han,1 Q. Chen.2

    1Department of Liver Surgery, Renji Hospital, Shanghai, China; 2Department of Pediatric Surgery, Shanghai Children Medical Center, Shanghai, China.

    Purpose: The purpose of this study was to evaluate the prognosis of interventional treatment through inferior mesenteric vein (IMV) and other treatments systemically for acute…
  • 2015 American Transplant Congress

    Clinical Utility of Allospecific CD154+T-Cells in Children With Liver Or Intestine Transplantation (LTx, ITx)

    K. Soltys, G. Bond, G. Mazariegos, C. Ashokkumar, K. Dirling, L. O'Toole, P. Kachmar, T. Hartle, D. Martin, C. Trautz, R. Sindhi.

    Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Background: Allospecific CD154+T-cytotoxic memory (CD154+TcM) have completed investigational evaluation as predictors of acute cellular rejection in children with LTx or ITx.Purpose: To evaluate CD154+TcM** as…
  • 2015 American Transplant Congress

    Mechanisms Underlying Treg Dysfunction in DAIH- Role for PD-L1?

    A. Arterbery,1 M. Martinez,2 S. Lobritto,2 Y. Avitzur,3 K. Raddassi,1 M. Kleinewietfeld,4 U. Ekong.1

    1Yale, NH; 2Columbia, NY; 3HSC, Toronto, Canada; 4Dresden University of Technology, Dresden, Germany.

    Background: we have previously shown that ex vivo Tregs from patients with DAIH demonstrate differentiation plasticity towards TH17. To understand the mechanisms underlying this we…
  • 2015 American Transplant Congress

    Pubertal Development in Pediatric Kidney Transplant Patients Receiving Everolimus Or Conventional Immunosuppression

    L. Pape,1 T. Ahlenstiel-Grunow,1 A. Zapf,2 M. Mynarek,3 J. Förster.1

    1Pediatric Nephrology, Hannover Medical School, Hannover, NDS, Germany; 2Medical Statistics, University Medical Center Göttingen, Göttingen, NDS, Germany; 3Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    TOR inhibitors (mTORi) have been discussed to eventually influence pubertal development after pediatric kidney transplantation (Tx).This is the first trial to compare pubertal development in…
  • 2015 American Transplant Congress

    Effective Long-Term Prophylaxis against De Novo Hepatitis B With Hepatitis B Vaccination in Pediatric Recipients of HbcAb-Positive Liver Grafts

    S. Lee, J.-M. Kim, G.-S. Choi, C.-H. Kwon, J.-W. Joh, S.-K. Lee.

    Department of Surgery, Samsung Medical Center, Seoul, Korea.

    Background) Controversy still exists concerning the use of livers from hepatitis B surface antigen-negative (HBsAg-)/hepatitis B core antibody-positive (HBcAb+) donors for liver transplantation (LT). We…
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