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American Transplant Congress abstracts

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Articles tagged "Pediatric"

  • 2015 American Transplant Congress

    Steroid Free Immunosuppression Protocol in Pediatric Kidney Transplant Recipients Using Alemtuzumab: A Retrospective Single Center Study

    R. Shah,1 Z. Kadry,1 S. Wassner,2 D. Kees-Folts,2 M. Freeman,2 P. Freeman,1 B. Olenowski,1 A. Jain.1

    1Surgery, Hershey Medical Center, Hershey, PA; 2Pediatric Nephrology, Hershey Medical Center, Hershey, PA.

    Background: Steroid free immunosuppression is attractive in pediatric kidney transplantation (KTx). Aim of the present study is to examine the patient survival, graft survival, rate…
  • 2015 American Transplant Congress

    Implementation of Pre-Transplant Infectious Disease Risk Assessment: Sustained Success With Rapid-Cycle Improvement

    L. Danziger-Isakov, S. Blum, D. Dahale, B. Morrow, R. Rengering, D. Schoborg, S. Stark, E. Wells, A. Lorts, U. Kotagal, J. Bucuvalas.

    Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

    Pre-transplant infectious disease risk assessment can identify and mitigate potential risk for transplant candidates to improve post-transplant outcomes. We aimed to improve pre-transplant ID risk…
  • 2015 American Transplant Congress

    Risk Factors for Acute Cellular Rejection for Pediatric Kidney Transplant Recipients

    D. Cote,1 I. Bobanga,1 B. Vogt,2 K. Dell,2 R. Cunningham III,2 K. Noon,1 V. Humphreville,1 E. Sanchez,1 J. Schulak,1 K. Woodside.1

    1Department of Surgery, Case Western Reserve University & University Hospitals, Cleveland, OH; 2Department of Pediatrics, Case Western Reserve University & University Hospitals, Cleveland, OH.

    Background: Acute cellular rejection (ACR) potentially shortens the life of a kidney allograft. We sought to determine risk factors associated with the development of ACR…
  • 2015 American Transplant Congress

    Late Rejection in Pediatric Heart Transplantation: The Importance of Medical Adherence

    A. Letica, W. Zuckerman, L. Addonizio, J. McAllister, T. Lee, M. Richmond.

    Division of Pediatric Cardiology, Columbia University, New York, NY.

    While the incidence of early rejection (<1 yr post-transplant) after pediatric heart transplant (HT) has decreased, late rejection (> 1 yr post-transplant) remains a constant…
  • 2015 American Transplant Congress

    Transplantation of Neonatal En-Bloc Kidneys: Do They Grow and Are They Subject to Hyperfiltration Injury?

    J. Woloszyn, C. Santhanakrishnan, C. Troppmann, A. DeMattos, B. Gallay, J. McVicar, J. Sageshima, R. Perez.

    UC Davis Transplant Center, Sacramento, CA.

    Importance:Neonatal Intensive Care Unit (NICU) kidney donation is rare but a potentially significant kidney source. Concerns with using these small kidneys include the risk for…
  • 2015 American Transplant Congress

    Identifying the “Operational Tolerant” Pediatric Liver Transplant Recipient by Cytometry by Time-of-Flight

    A. Lau,1,2 M. Vitalone,1 K. Haas,3 T. Shawler,1 C. Esquivel,1 O. Martinez,1 R. Castillo,3 S. Krams.1

    1Surgery, Division of Abdominal Transplantation, Stanford University, Stanford, CA; 2Pediatrics, Div. Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, San Francisco, CA; 3Pediatrics, Div. Gastroenterology, Hepatology, and Nutrition, Stanford University, Stanford, CA.

    Liver allografts are known to be well tolerated and indeed, some recipients of liver allografts retain stable graft function in the absence of immunosuppression. The…
  • 2015 American Transplant Congress

    Donor Age and Late Rejection Are Associated With the Development of Graft Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients

    W. Zuckerman, M. Richmond, T. Lee, L. Addonizio.

    Division of Pediatric Cardiology, Columbia University Medical Center, New York, NY.

    Purpose: Graft coronary artery vasculopathy (GCV) is one of the major causes of morbidity and mortality in pediatric heart transplant (HT) recipients, and in fact…
  • 2015 American Transplant Congress

    New Insights in Clinical and Genetic Determinants of Longitudinal Dose-Corrected CNI Exposure in Children After Renal Transplantation

    N. Knops,1 M. van Dyck,1 E. Levtchenko,1 D. Kuypers,2 J. Herman.1

    1Pediatric Nephrology and Solid Organ Transplantation, University Hospitals Leuven, Leuven, Belgium; 2Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium.

    Purpose: Calcineurin-inhibitors (CNI) have a narrow therapeutic index and dosing is difficult due to inter- and intra-individual variation in pharmacokinetics (PK). Polymorphisms in genes involved…
  • 2015 American Transplant Congress

    Implementation of Evidence-Based Guidelines for Cytomegalovirus Prevention in Pediatric Solid Organ Transplantation

    L. Danziger-Isakov, T. Hemmelgarn, R. Kohli, D. Lazear, M. Lake, J. Goebel, C. Castleberry, J. Courter, S. Kacoshis, M. Schecter, D. Witte, E. Clark, J. Bucuvalas.

    Cincinnati Children's, Cincinnati.

    Optimal strategies to prevent cytomegalovirus (CMV) disease after pediatric solid organ transplantation (SOT) in a cost effective manner are uncertain. We evaluated the frequency of…
  • 2015 American Transplant Congress

    Pediatric Liver Transplantation for Metabolic Diseases: Analysis of Children's Hospital of Pittsburgh (CHP) and United Network for Organ Sharing (UNOS) Databases

    A. Ganoza, B. Shneider, R. Sindhi, K. Soltys, G. Bond, G. Vockley, Q. Sun, G. Mazariegos.

    Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Purpose: To analyze long term patient survival outcomes after primary LTx for metabolic disease in children <21 years at CHP (1981-2014) and the multi-center UNOS…
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