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Articles tagged "Pediatric"

  • 2016 American Transplant Congress

    Intestinal Retransplantation in Children: Single Center Experience.

    N. Celik,1 F. Vyas,1 G. Bond,1 K. Soltys,1 J. Rudolph,2 R. Sindhi,1 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Intestinal Care and Rehabilitation Center, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Aim: To analyze the patient and graft characteristics and improvement in patient outcomes for intestinal retransplantation (Re-ITx) in the era of induction immunosuppression with the…
  • 2016 American Transplant Congress

    Adherence Patterns in Adolescent and Young Adult Kidney Transplant Recipients.

    J. Boucquemont,1,2 B. Foster,1,2 The TAKE-IT Investigators.

    1Research Inst. of the McGill Univ. Health Centre, Montréal, QC, Canada; 2Dept of Epidemiology, Biostatistics and Occupational Health, McGill Univ., Montreal, QC, Canada.

    Poor adherence to immunosuppressive medications limits long-term renal allograft survival. Using data from the 3-month run-in (no intervention) of the randomized trial TAKE-IT, which tests…
  • 2016 American Transplant Congress

    Treatment for AMR and DSA: A Center Based Review of Pediatric Orthotopic Heart Transplant Recipients.

    D. Drogalis-Kim,1 M. Hickey,2 J. Alejos,1 E. Reed,2 N. Halnon.1

    1Department of Pediatric Cardiology, UCLA, Los Angeles, CA; 2Department of Immunogenetics, UCLA, Los Angeles, CA.

    PURPOSE: The aim of this study was to retrospectively analyze the clinical course of pediatric orthotopic heart transplant patients diagnosed with antibody mediated rejection (AMR+)…
  • 2016 American Transplant Congress

    Using 3D Printing in Complex Pediatric Renal Transplantation.

    P. Chandak,1 N. Byrne,2 N. Karunanithy,3 C. Callaghan,1 I. Mushtaq,4 S. Marks,4 J. Stajonovic,1 Z. Ahmed,1 N. Kessaris,1 N. Mamode.1

    1Transplantation, Guy's, Evelina & Great Ormond Street, London, United Kingdom; 2Imaging Sciences, King's College London, London, United Kingdom; 3Interventional Radiology, Guy's, London, United Kingdom; 4Paediatric Nephrology and Urology, Great Ormond Street, London, United Kingdom.

    Introduction:Structural complexities can render graft implantation infeasible in small paediatric recipients. Surgical decision-making currently relies on 3D medical imaging which limits evaluation of structures by…
  • 2016 American Transplant Congress

    Conversion to Once-Daily Tacrolimus in Stable Pediatric Liver Transplantation Recipients.

    N. Lee, S. Lee, C.-W. Cho, J. Lee, J. Lee, J. Kim, G.-S. Choi, C. Kwon, J.-W. Joh, S.-K. Lee.

    Department of Surgery Organ Transplant Center, Samsung Medical Center, Seoul, Republic of Korea.

    Purpose: Pediatric patients are known to have lower compliance than adult patients. Once-daily formulation of tacrolimus may increase compliance in pediatric liver transplant recipients. The…
  • 2016 American Transplant Congress

    Conditional Long Term Intestine Patient and Graft Survival Is Improving Under rATG Immunosuppression in Pediatric Intestine Transplantation.

    N. Celik,1 F. Vyas,1 G. Bond,1 K. Soltys,1 J. Rudolph,2 R. Sindhi,1 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Intestinal Care and Rehabilitation Center, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Aim: We reviewed conditional graft survival and short and long term improvements in children receiving rATG (rabbit anti-thymocyte globulin) immunosuppression for intestine transplantation at a…
  • 2016 American Transplant Congress

    Angiotensin II Type 1 Receptor Antibodies Are Associated with Allograft Loss in Pediatric Renal Transplantation.

    M. Pearl,1 Q. Zhang,2 M. Palma Diaz,3 J. Grotts,4 J. Brook,4 D. Gjertson,2 P. Weng,1 E. Reed,2 E. Tsai.1

    1Pediatrics, University of California-Los Angeles, Los Angeles, CA; 2Pathology and Laboratory Medicine, University of California-Los Angeles, Los Angeles, CA; 3Anatomic & Clinical Pathology, University of California-Los Angeles, Los Angeles, CA; 4Biostatistics, University of California-Los Angeles, Los Angeles, CA.

    Background: Angiotensin II type 1 receptor antibody (AT1R-Ab) is associated with vascular injury and allograft failure in adult kidney transplantation. Its role in pediatric transplantation…
  • 2016 American Transplant Congress

    Anti-HLA Antibody Composition and Outcomes in Pediatric Heart Transplant Recipients with a Positive Cross-Match.

    P. Jindra,1 S. Nicholas,2 J. Chappelle,1 T. Humlicek,2 K. Hosek,2 J. Heinle,2 S. Denfield,2 A. Jeewa,2 R. Kerman,1 W. Dreyer.2

    1Surgery Immune Evaluation Lab, Baylor College of Medicine, Houston, TX; 2Pediatrics, Baylor College of Medicine, Houston, TX.

    Purpose: Utilization of positive (+) cross-match (XM) hearts is tempting when shortages of pediatric donor hearts exist, especially for patients with high pre-transplant panel reactive…
  • 2016 American Transplant Congress

    Low Pretransplant BMI/Weight and Changes in Posttransplant T Cell Exhaustion Levels Are Associated with Viremia/Viral Infection in Pediatric Kidney Transplantation in the First Post-Transplant Year – A Report from the IMPACT Study Consortium.

    R. Ettenger,1 H. Chin,2 P. Grimm,3 K. Kesler,2 E. Reed,4 M. Sarwal,5 B. Warshaw,6 E. Tsai,1 A. Kirk.7

    1Pediatrics, UCLA, LA, CA; 2Rho, Chappel Hill, NC; 3Pediatrics, Stanford Univ, Palo Alto, CA; 4Pathology, UCLA, LA, CA; 5Surgery, UCSF School of Medicien, SF, CA; 6Pediatric Nephrolgoy, Children's Healthcare of Atlanta, Atlanta, GA; 7Surgery, Duke University, Durham, NC.

    Viral consequences of immunosuppression (IS) in pediatric(ped)kidney(kid)transplantation(Tx)patients(pts) are not fully known. We prospectively examined the immunologic and infectious (inf) history of 106 ped Tx pts…
  • 2016 American Transplant Congress

    Use of En-Bloc Vascularized Rectus Sheath Allograft to Achieve Abdominal Closure in Pediatric Liver and Multivisceral Transplantation.

    J. Reddy, A. Rege, D. Vikraman, B. Collins, T. Brennan, S. Knechtle, D. Sudan, K. Ravindra.

    Surgery, Duke University, Durham, NC.

    Background: Abdominal wall closure is often challenging in pediatric liver (LT) and multivisceral transplantation (MVT) due to size discrepancy of donor & recipient and abdominal…
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