2017 American Transplant Congress
Impact of Six-Month Surveillance Biopsies and Monitoring in Pediatric Renal Transplant Recipients.
Purpose: Evaluate the utility of surveillance biopsies and monitoring 6 months post-transplant.Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011–10/2015…2017 American Transplant Congress
Isolated Angiotensin II Receptor Type I Antibodies (AT1R) Are Not Associated with Active Antibody Mediated Rejection (ABMR) in Pediatric Renal Transplant Recipients.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Intro: Donor specific antibodies (DSAs) detected post transplant are associated with ABMR and graft dysfunction. The role of non-HLA antibodies especially angiotensin II receptor type…2017 American Transplant Congress
Inflammatory Cytokines Are Associated with Angiotensin II Type 1 Receptor Antibodies and Vascular Inflammation in Pediatric Renal Transplantation.
1University of California, Los Angeles, CA; 2Duke University, Durham, NC
Background: We recently found that angiotensin II type 1 receptor antibody (AT1R-Ab) was associated with decreased renal function in pediatric renal transplant recipients independent of…2017 American Transplant Congress
EBV-Specific CD8+ T Cells from Pediatric Thoracic vs Abdominal Transplant Recipients Are Shaped Differently by the Chronic EBV Loads with Potential Impact on the Risk of PTLD.
Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). Chronic high EBV viral load (HVL) carriers have…2017 American Transplant Congress
Acute Renal Replacement Therapy in Pediatric Liver Transplantation: A Predictor of Increased Risk.
1Surgery, UCLA, Los Angeles, CA; 2Pediatric Gastroenterology, UCLA, Los Angeles, CA
BackgroundAmong pediatric patients (≤18 yrs) awaiting liver transplantation (LT), limited data exist on the prognostic significance of acute (<90d) renal replacement therapy (RRT) prior to…2017 American Transplant Congress
Superior Long-Term Hypertension Management in Pediatric Kidney Transplant Recipients with Bilateral Native Nephrectomies.
Introduction: Native nephrectomy in pediatric kidney transplant recipients is performed for congenital anomalies, proteinuria, intractable hypertension, malignancy, and chronic infection. Post-transplant hypertension requiring medical management…2017 American Transplant Congress
Impairment of Glucose Tolerance After Pediatric Kidney Transplant Is Associated with Worse Systemic Insulin Sensitivity Rather Than Fall in Insulin Secretion.
Renal and Genitourinary Surgery, Hokkaido University, Sapporo, Hokkaido, Japan
Introduction and Objective: Tacrolimus and steroid are considered to affect insulin secretion and insulin sensitivity, respectively, resulting in worse glucose tolerance after pediatric kidney transplant…2017 American Transplant Congress
Clinical and Histopathologic Features of Antibody Mediated Rejection (ABMR) in Highly Sensitized (HS) vs Non-Sensitized (NS) Pediatric Renal Transplant Recipients.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
Background: The presence of preformed donor-specific antibody (pDSA) in HS pts and development of de-novo DSA (dnDSA) in NS patients are risk factors for ABMR.…2017 American Transplant Congress
Efficacy and Safety of Everolimus with Reduced-Exposure Tacrolimus and Corticosteroid Withdrawal in De Novo Pediatric Renal Transplant Recipients: 12-Month Results from the CRADLE Study.
PURPOSE: We present 12-month (M) results from the CRADLE study (NCT01544491) that assessed efficacy and safety of everolimus (EVR) with reduced-exposure tacrolimus (rTAC) and early…2017 American Transplant Congress
Long-Term Pediatric Live-Donor Liver Transplantation Survivors: Patient and Allograft Outcomes.
Aim: To determine the patient and allograft outcomes at 5 years after pediatric live-donor liver transplantation (LDLT).Methods: Children with a minimum of 5-year survival post-transplantation…
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