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American Transplant Congress abstracts

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Articles tagged "Pediatric"

  • 2019 American Transplant Congress

    Circulating De Novo Donor Specific Antibodies and Carotid Intima-Media Thickness in Pediatric Kidney Transplant Recipients

    K. Sgambat1, S. Clauss2, A. Moudgil1

    1Nephrology, Children's National, Washington DC, DC, 2Cardiology, Children's National, Washington DC, DC

    *Purpose: Emerging evidence suggests that circulating de novo donor specific anti-HLA antibodies (dnDSA) may be associated with increased risk of accelerated systemic arteriosclerosis and major…
  • 2019 American Transplant Congress

    Organ Procurement Organization Surgeon Improves Utilization of Livers from Pediatric Donors

    M. MacConmara1, J. Reese2, T. Anthony2, A. Aqul3, S. Hanish1, P. Vagefi1, D. Desai1, C. Hwang1

    1Surgery (Division of Surgical Transplantation)I, UT Southwestern Medical Center, Dallas, TX, 2Southwest Transplant Alliance, Dallas, TX, 3Childrens Medical Center, Dallas, TX

    *Purpose: Pediatric liver transplant centers tend to send their own procurement team for organ assessment and recovery. TXSB organ procurement organization (OPO) hired a full-time…
  • 2019 American Transplant Congress

    A Novel Protocol to Produce Massive Amounts of Autologous Thymus-Derived Treg Cells (ThyTreg) to Be Employed as Cellular Therapy in Heart Transplanted Children: A New Paradigm for the Prevention of Graft Rejection

    E. Bernaldo de Quirós1, R. López1, V. Pérez1, M. Clemente2, J. Gil-Jaurena3, M. Camino4, N. Gil4, E. Panadero4, C. Medrano4, M. Pion1, R. Correa-Rocha1

    1Laboratory of Immune-regulation, Instituto de Investigación Sanitaria Gregorio Marañón (IISGM), Madrid, Spain, 2Cell Culture Unit, Instituto de Investigación Sanitaria Gregorio Marañón (IISGM), Madrid, Spain, 3Pediatric Cardiac Surgery Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 4Pediatric Cardiology Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    *Purpose: Immune allograft rejection remains the main obstacle to successful transplants. Although transfer of regulatory T cells (Treg) has acquired growing interest in achieving indefinite…
  • 2019 American Transplant Congress

    Changes in Kidney Offer Acceptance for Pediatric Candidates Post-KAS

    M. Bowring, K. Jackson, J. Garonzik-Wang, D. Segev, A. Massie

    Johns Hopkins University, Baltimore, MD

    *Purpose:Stakeholders have expressed concerns regarding kidney transplant rates for pediatric candidates under KAS. To better understand what might be driving potential declines in access, we…
  • 2019 American Transplant Congress

    Primary Indications and Waitlist Status for Pediatric Living Donor Liver Transplants

    K. Goli1, K. Hosek2, A. Rana3, J. Goss3, T. Miloh3

    1Rice University, Houston, TX, 2Texas Children's Hospital, Houston, TX, 3Abdominal Transplant, Baylor College of Medicine/Texas Children's Hospital, Houston, TX

    *Purpose: Since 1989, living donor liver transplantation (LD) has been used for a selected population and has shown improved long-term graft survival. The aim was…
  • 2019 American Transplant Congress

    Slowed Progression of Maximal Intimal Thickening by Intravascular Ultrasound after Initiation of Sirolimus

    A. Putschoegl1, K. Campbell1, M. Everitt1, S. Miyamoto1, B. Pietra2, S. Auerbach1

    1Children's Hospital Colorado, Aurora, CO, 2University of Florida Health, Gainesville, FL

    *Purpose: Evidence in adult heart transplant (HT) patients (pt) shows that initiating sirolimus (SRL) slows progression of cardiac allograft vasculopathy (CAV) measured by intravascular ultrasound…
  • 2019 American Transplant Congress

    Efficacy and Safety of Everolimus in Pediatric Renal Transplantation

    T. Sandes-Freitas1, B. Pantoja2, M. Custódio2, A. Goersch Silva3, R. Costa2, M. Sales3, R. Esmeraldo3

    1Hospital Geral de Fortaleza / Federal University of Ceara, Fortaleza, Brazil, 2Federal University of Ceará, Fortaleza, Brazil, 3Hospital Geral de Fortaleza, Fortaleza, Brazil

    *Purpose: There are scarce evidence on the efficacy and safety of everolimus (EVR)-based regimens in pediatric kidney transplantation (KT).*Methods: This single center retrospective cohort analyzed…
  • 2019 American Transplant Congress

    Metabolic Liver Transplantation – Can We Afford It?

    N. Yazigi1, W. Fujiwara2

    1Transplant Institute, MedStar Georgetown University Hospital, Washigton, DC, 2Georgetown University Medical School, Washigton, DC

    *Purpose: Despite major improvement in medical and nutritional care of pediatric patients suffering from intoxication inherited metabolic disorders, their long term outcomes remain guarded. Liver…
  • 2019 American Transplant Congress

    Impact of the Pediatric End-Stage Liver Disease Growth Failure Threshold on Waitlist Mortality in Children Awaiting Liver Transplant

    S. M. Swenson, J. P. Roberts, S. Rhee, E. R. Perito

    University of California, San Francisco, San Francisco, CA

    *Purpose: To examine the impact on waitlist mortality of Pediatric End-Stage Liver Disease (PELD)’s incorporation of growth failure (GF) as a threshold variable—present or absent…
  • 2018 American Transplant Congress

    BK Polyomavirus (BKPyV)-Specific T Cells as a Diagnostic and Prognostic Marker for BKPyV-Infections after Pediatric Kidney Transplantation

    T. Ahlenstiel-Grunow,1 M. Sester,2 U. Sester,3 L. Pape.1

    1Pediatric Nephrology, Hannover Medical School, Hannover, Germany; 2Transplant and Infection Immunology, Saarland University, Homburg, Germany; 3Internal Medicine IV, Saarland University, Homburg, Germany.

    After kidney transplantation (KTx) immunosuppressive therapy causes an impaired cellular immune defense resulting in an increased risk of BKPyV-nephropathy (BKPyVAN). Prognostic markers for the outcome…
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