Articles tagged "Pediatric"

2019 American Transplant Congress
Treg Plasticity is Induced by ENV,HERV1_I and UPR Activation in De Novo Autoimmune Hepatitis
J. Yao¹, A. Ling¹, A. Arterbery¹, Y. Avitzur², S. Lobritto³, M. Martinez³, U. Ekong¹
¹Yale University, New Haven, CT, ²University of Toronto, Toronto, ON, Canada, ³Columbia University, New York, NY
*Purpose: FOXP3+regulatory T cells (Tregs) are not a terminally differentiated population & can, under specific environmental conditions, acquire the phenotype of effector T cells. We…
2019 American Transplant Congress
Growth and Function of En Bloc Kidney Transplantation: A Single-Center Experience
H. Mo¹, J. Ha¹, A. Han¹, S. Min¹, S. Min¹, S. Ahn¹, I. Ha², H. Kang², S. Kim³
¹Department of surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ²Pediatric Nephrology, Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of surgery, Myongji Hospital, Seoul, Korea, Republic of
*Purpose: To overcome organ shortage, using en bloc renal allografts is widely accepted strategy. In this study we review the results of en bloc kidney…
2019 American Transplant Congress
Successful Kidney Transplantation in a Small Child with an Atretic Inferior Vena Cava
J. A. Geha¹, J. D. Geha¹, M. Goss¹, M. L. Kueht¹, R. T. Cotton¹, J. A. Goss¹, A. Rana¹, C. A. O'Mahony¹, P. Srivaths², E. Brewer², N. N. Galvan¹
¹Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, ²Department of Pediatrics, Baylor College of Medicine, Houston, TX
*Purpose: Kidney transplantation is the treatment of choice in pediatric patients with end stage renal disease. This population presents technical challenges particularly in those less…
2019 American Transplant Congress
Pediatric Heart and Lung Graft Loss during the “High-Risk Age Window”
J. Long¹, J. Motter¹, K. R. Jackson¹, M. Kosztowski¹, B. Orandi², X. Luo¹, K. Van Arendonk³, A. Massie¹, E. Bush¹, R. S. Higgins¹, D. L. Segev¹, J. M. Garonzik-Wang¹
¹Johns Hopkins School of Medicine, Baltimore, MD, ²University Of Alabama at Birmingham, Birmingham, AL, ³Children’s Hospital of Wisconsin-Milwaukee Campus, Milwaukee, WI
*Purpose: Pediatric kidney transplant recipients experience a high-risk age window of increased graft loss during late adolescence and early adulthood (17-24 years), termed emerging adulthood.…
2019 American Transplant Congress
Contemporary US Prevalence and Outcomes of Pneumocystis jirovecii Pneumonia and Toxoplasmosis in Pediatric Solid Organ and Hematopoietic Cell Transplantation Recipients
M. I. Ardura¹, J. Stanek², B. Hanisch³, B. Hanisch⁴, K. Sprott⁵, H. Rangarajan⁶
¹Pediatrics, Infectious Diseases & Host Defense, Nationwide Children's Hospital & The Ohio State University, Columbus, OH, ²Pediatrics, Biostatistics, Nationwide Children's Hospital, Columbus, OH, ³Pediatrics, Infectious Diseases, Children's National Health System, Washington, DC, ⁴Pediatrics, Infectious Diseases, Children's National Health System & The George Washington University, Washington, DC, DC, ⁵Pediatrics, Pharmacy, Medical University of South Carolina, Charleston, SC, ⁶Pediatrics, Hematology/Oncology/HCT, Nationwide Children's Hospital & The Ohio State University, Columbus, OH
*Purpose: We sought to evaluate the contemporary prevalence and outcomes of Pneumocystis jirovecii pneumonia (PCP) and toxoplasmosis among pediatric transplantation recipients in the US in…
2019 American Transplant Congress
Urinary Biomarkers- CXCL9 and CXCL10 for Non-Invasive, Early Diagnosis of Rejection in Pediatric Renal Transplantation
R. P. George¹, B. Hanberry², I. Dave², B. Lee², R. Garro¹, C. McCracken², B. Warshaw¹
¹Pediatrics, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, ²Pediatrics, Emory University, Atlanta, GA
*Purpose: Renal transplantation is the treatment of choice for End Stage Renal Disease, but requires strict medication adherence and lifelong surveillance for rejection, infection and…
2019 American Transplant Congress
Epitope-Based Matching in Pediatric Kidney Transplantation
C. Boussard¹, M. Ould Rabah², O. Boyer², M. Macher¹, J. Taupin³, J. Hogan⁴
¹Department of Pediatric Nephrology, Robert Debre hospital, APHP, Paris, France, ²Department of Pediatric Nephrology, Necker Enfants-Malades, APHP, Paris, France, ³Department of Immunology, Saint-Louis Hospital, APHP, Paris, France, ⁴Transplant Research Center, Department of Surgery, Emory University, ATLANTA, GA
*Purpose: Following the allocation of a transplant by the allocation system, each pediatric transplant team reviews the proposal and decides based on various criteria whether…
2019 American Transplant Congress
Utilization of Small Pediatric Donor Kidneys to Improve Access to Kidney Transplantation for Underappreciated Uremic Children in China
X. Su¹, W. Shang², L. Liu¹, Y. Feng², H. Zhang¹, J. Li¹, Q. Fu¹, X. Pang², G. Feng², C. Wang¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Kidney Transplantation Unit, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
*Purpose: We previously reported that children with end-stage renal disease had less chance to access to kidney transplantation from deceased donors in China. The number…
2019 American Transplant Congress
Ex Vivo Resection And Autologous Liver Transplantation As Management Concept For Extensive Malignancy
K. Bruestle¹, A. Griesemer², S. Lobritto², M. Martinez², J. Vittorio², D. Yamashiro², E. Bacha³, T. Kato²
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Columbia Center for Liver Disease and Transplantation, Columbia University Medical Center, New York City, NY, ³Morgan Stanley Children's Hospital, Columbia University Medical Center, New York City, NY
*Purpose: Neuroblastomas are rare neural crest derived tumors which contribute disproportionally to childhood morbidity and mortality. Surgical resection remains standard treatment, however adequate resection is…
2019 American Transplant Congress
Increase in 48 Month Cumulative Acute Rejection Rates in the Most Recent Cohort: The 2018 Transplant Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)
V. Dharnidharka¹, C. Cramer², A. Chua³, A. Moudgil⁴, K. Martz⁵, T. Blydt-Hansen⁶, J. Smith⁷, A. Neu, on Behalf of The NAPRTCS Investigators⁸
¹Washington University in St. Louis, Saint Louis, MO, ²Mayo Clinic, Rochester, MN, ³Duke University, Durham, NC, ⁴Children's National Medical Center, Washington, DC, ⁵Emmes Corporation, Rockville, MD, ⁶BC Children's Hospital, Vancouver, BC, ⁷Seattle Children's Hospital, Seattle, WA, ⁸Johns Hopkins University, Baltimore, MD
*Purpose: The NAPRTCS registry has collected data on children receiving kidney transplants in North America since 1987. The registry has served to document and influence…