Articles tagged "Pediatric"

2019 American Transplant Congress
Ganciclovir Based Prophylaxis against Cytomegalovirus Viremia in Pediatric Renal Transplant Patients: A Systematic Review and Meta-Analysis
B. CHATANI¹, W. Glaberson², Z. Nemeth³, L. Tamariz⁴, I. A. Gonzalez¹
¹Pediatric Infectious Disease, University of Miami Miller School of Medicine, Miami, FL, ²Pediatric Nephrology, University of Miami Miller School of Medicine, Miami, FL, ³Health Informatics, University of Miami Miller School of Medicine, Miami, FL, ⁴Population Health and Computation Medicine, University of Miami Miller School of Medicine, Miami, FL
*Purpose: Cytomegalovirus (CMV) disease continues to stand as a significant threat to the longevity of renal transplants in children. More pediatric recipients are CMV negative…
2019 American Transplant Congress
Intraoperative Blood Loss and Transfusion during Pediatric Liver Transplantation: A Single Center Experience
J. A. Villarreal¹, D. Yoeli², J. Yoeli³, R. Ackah⁴, R. Sigireddi¹, M. Kueht¹, N. Galvan¹, R. Cotton¹, A. Rana¹, C. O’Mahony¹, J. Goss¹
¹Surgery, Baylor College of Medicine, Houston, TX, ²Surgery, University of Colorado School of Medicine, Denver, CO, ³Pediatrics, University of Colorado School of Medicine, Denver, CO, ⁴Surgery, The Ohio State University College of Medicine, Columbus, OH
*Purpose: The aim of this study is to identify risk factors for massive intraoperative blood loss and transfusion in pediatric liver transplant recipients and describe…
2019 American Transplant Congress
Steadily Dropping Malignancy Rates after Pediatric Kidney Transplantation Have Now Reversed in the Most Recent Era: A Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)
V. Dharnidharka¹, C. Cramer², A. Chua³, A. Moudgil⁴, K. Martz⁵, T. Blydt-Hansen⁶, J. Smith⁷, A. Neu, on behalf of the NAPRTCS Investigators⁸
¹Washington University in St. Louis, Saint Louis, MO, ²Mayo Clinic, Rochester, MN, ³Duke University, Durham, NC, ⁴Children's National Medical Center, Washington, DC, ⁵Emmes Corporation, Rockville, MD, ⁶BC Children's Hospital, Vancouver, BC, Canada, ⁷Seattle Children's Hospital, Seattle, WA, ⁸Johns Hopkins University, Baltimore, MD
*Purpose: In general, malignancies are very rare in children, compared to older adults. The NAPRTCS registry has collected data on children receiving kidney transplants in…
2019 American Transplant Congress
De Novo Complement-Activating Donor Specific Antibodies in Pediatric Renal Transplant Recipients Are Highly Responsive to Therapy
V. Sigurjonsdottir, A. Chaudhuri, P. Grimm
Pediatric Nephrology, Stanford, Los Altos, CA
*Purpose: Antibody mediated rejection remains a common cause for pediatric renal allograft loss. After recognizing that graft failure was more common in our pediatric renal…
2019 American Transplant Congress
Pediatric Liver Retransplantation: Prognostic Scoring Tool
A. Kuhne, D. Vock, J. Back, K. Ramanathan, A. Matas, S. Chinnakotla
University of Minnesota Medical School, Minneapolis, MN
*Purpose: Liver Re-transplantation is the only option for survival when a transplanted liver fails. However, Re-transplantion of the liver remains a challenge given the scarcity…
2019 American Transplant Congress
Mycophenolic Acid Area under the Curve Monitoring via Limited Sampling Strategy in Pediatric Heart Transplant Recipients
S. Crow, S. H. Dahl, J. N. Johnson
Mayo Clinic, Rochester, MN
*Purpose: The study aim was to investigate exposure to mycophenolic acid (MPA), the active metabolite of mycophenolate mofetil (MMF), after pediatric orthotopic heart transplantation (pOHT).…
2019 American Transplant Congress
Circulating De Novo Donor Specific Antibodies and Carotid Intima-Media Thickness in Pediatric Kidney Transplant Recipients
K. Sgambat¹, S. Clauss², A. Moudgil¹
¹Nephrology, Children's National, Washington DC, DC, ²Cardiology, Children's National, Washington DC, DC
*Purpose: Emerging evidence suggests that circulating de novo donor specific anti-HLA antibodies (dnDSA) may be associated with increased risk of accelerated systemic arteriosclerosis and major…
2019 American Transplant Congress
Organ Procurement Organization Surgeon Improves Utilization of Livers from Pediatric Donors
M. MacConmara¹, J. Reese², T. Anthony², A. Aqul³, S. Hanish¹, P. Vagefi¹, D. Desai¹, C. Hwang¹
¹Surgery (Division of Surgical Transplantation)I, UT Southwestern Medical Center, Dallas, TX, ²Southwest Transplant Alliance, Dallas, TX, ³Childrens Medical Center, Dallas, TX
*Purpose: Pediatric liver transplant centers tend to send their own procurement team for organ assessment and recovery. TXSB organ procurement organization (OPO) hired a full-time…
2019 American Transplant Congress
A Novel Protocol to Produce Massive Amounts of Autologous Thymus-Derived Treg Cells (ThyTreg) to Be Employed as Cellular Therapy in Heart Transplanted Children: A New Paradigm for the Prevention of Graft Rejection
E. Bernaldo de Quirós¹, R. López¹, V. Pérez¹, M. Clemente², J. Gil-Jaurena³, M. Camino⁴, N. Gil⁴, E. Panadero⁴, C. Medrano⁴, M. Pion¹, R. Correa-Rocha¹
¹Laboratory of Immune-regulation, Instituto de Investigación Sanitaria Gregorio Marañón (IISGM), Madrid, Spain, ²Cell Culture Unit, Instituto de Investigación Sanitaria Gregorio Marañón (IISGM), Madrid, Spain, ³Pediatric Cardiac Surgery Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ⁴Pediatric Cardiology Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain
*Purpose: Immune allograft rejection remains the main obstacle to successful transplants. Although transfer of regulatory T cells (Treg) has acquired growing interest in achieving indefinite…
2019 American Transplant Congress
Changes in Kidney Offer Acceptance for Pediatric Candidates Post-KAS
M. Bowring, K. Jackson, J. Garonzik-Wang, D. Segev, A. Massie
Johns Hopkins University, Baltimore, MD
*Purpose:Stakeholders have expressed concerns regarding kidney transplant rates for pediatric candidates under KAS. To better understand what might be driving potential declines in access, we…