Articles tagged "Pediatric"

2019 American Transplant Congress
Donor-Derived Cell-Free DNA (dd-cfDNA) Course after Rejection in Pediatric Kidney Transplant Recipients
R. D. Swinford¹, A. M. De Golovine¹, C. Bell¹, A. Pai¹, A. R. Edwards¹, S. Connor², J. S. Bynon¹
¹Pediatrics, UTHealth, McGovern Medical School, University of Texas at Houston, Houston, TX, ²Transplantation, Memorial Hermann Hospital, Houston, TX
*Purpose: Accurate identification of successful treatment for rejection (R) without repeat kidney biopsy (KB) in kidney transplantation is an unmet need. The few existing biomarkers…
2019 American Transplant Congress
Standardizing Blood Pressure Measurement across 17 Pediatric Transplant Centers: The Improving Renal Outcomes Collaborative
M. E. Seifert¹, R. Garro², R. P. George², G. Barletta³, C. W. Belsha⁴, A. Chaudhuri⁵, J. W. Goebel⁶, L. Wickman⁷, D. Matossian⁸, J. Misurac⁹, C. Nailescu¹⁰, C. R. Nguyen¹¹, M. Pearl¹², A. Pollack¹³, C. S. Pruette¹⁴, P. Singer¹⁵, P. S. Verghese¹⁶, B. A. Warady¹⁷, D. S. Dahale¹⁸, D. K. Hooper¹⁸
¹University of Alabama, Birmingham, AL, ²Emory University, Atlanta, GA, ³Phoenix Children's Hospital, Phoenix, AZ, ⁴Saint Louis University, St. Louis, MO, ⁵Stanford University, Stanford, CA, ⁶Children's Hospital Colorado, Aurora, CO, ⁷Michigan Medicine, Ann Arbor, MI, ⁸Lurie Children's Hospital, Chicago, IL, ⁹University of Iowa, Iowa City, IA, ¹⁰Riley Hospital For Children, Indianapolis, IN, ¹¹Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ¹²UCLA Mattel Children’s Hospital, Los Angeles, CA, ¹³Seattle Children's Hospital, Seattle, WA, ¹⁴Johns Hopkins University, Baltimore, MD, ¹⁵Cohen Children's Medical Center, New Hyde Park, NY, ¹⁶University of Minnesota, Minneapolis, MN, ¹⁷Children's Mercy Kansas City, Kansas City, MO, ¹⁸Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: We report efforts from the Improving Renal Outcomes Collaborative (IROC) to standardize appropriate BP measurement across 17 pediatric kidney transplant centers.*Methods: 17 centers participated…
2019 American Transplant Congress
De Novo Glomerulonephritis after Non Renal Abdominal Organ Transplantation
C. Farkas¹, R. B. Ettenger¹, J. Zuckerman², R. S. Venick³, P. Weng¹
¹Pediatric Nephrology, UCLA, Los Angeles, CA, ²Pathology, UCLA, Los Angeles, CA, ³Pediatric Gastroenterology, UCLA, Los Angeles, CA
*Purpose: Pediatric recipients of non renal abdominal organs may develop renal abnormalities of uncertain etiology. We describe for the first time de novo lupus-like glomerulonephritis…
2019 American Transplant Congress
Transport Medium Fluid Cultures in Paediatric Renal Transplantation: Are We Ready to Make a Consensus on Prophylaxis?
D. Furnell¹, S. Boyle¹, N. Kessaris², S. D. Marks¹, J. Stojanovic¹
¹Nephrology, Great Ormond Street Hospital, London, United Kingdom, ²Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
*Purpose: To establish the rate of positive transport medium fluid cultures and sensitivity to antibiotics in paediatric renal transplant recipients.*Methods: We analysed the electronic records…
2019 American Transplant Congress
Post-Transplant Lymphoproliferative Disorders in Pediatric Renal Transplant Recipients: Case Series of 5 Patients
M. E. Araujo¹, C. Metran¹, R. Cardoso¹, G. Araujo¹, T. De Paula¹, L. Cristofani², M. F. Pereira³, D. David⁴, A. Watanabe¹
¹Pediatric Nephrology, ICr HC FMUSP, São Paulo, Brazil, ²Pediatric Oncology, ICr HC FMUSP, São Paulo, Brazil, ³Pediatric Infectology, ICr HC FMUSP, São Paulo, Brazil, ⁴Anatomopathology, HC FMUSP, São Paulo, Brazil
*Purpose: Post-transplant Lymphoproliferative Disorders (PTLD) after solid organ transplantation is a complication of chronic immunosuppression (IS) and is generally associated with Epstein Barr virus (EBV)…
2019 American Transplant Congress
Pictogram Tool to Improve Medication Adherence in Heart Transplant Families with Limited English Proficiency and Low Health Literacy
A. C. Rothkopf¹, J. Chen², N. Jasiak-Panek³, K. Le³, A. Joong⁴, L. J. Addonizio¹
¹Pediatric Cardiology, Columbia University, New York, NY, ²Department of Pharmacy, Columbia University, New York, NY, ³Department of Pharmacy, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ⁴Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
*Purpose: Rejection in heart transplant recipients significantly limits long-term survival, impairs quality of life, and increases both direct and indirect costs of care. Preventing rejection…
2019 American Transplant Congress
Elevated Donor Derived Cell Free DNA (dd-cfDNA) Levels in the Presence of Donor Specific Antibodies (DSA) Are a Strong Predictor of Antibody Mediated Rejection (ABMR) in Pediatric Renal Transplant Recipients
D. Puliyanda¹, R. D. Swinford², H. Pizzo¹, J. Garrison¹, I. Kim¹, A. M. De Golovine², S. Jordan¹
¹Pediatric Nephrology, Cedars-Sinai Med Ctr, Los Angeles, CA, ²Pediatric Nephrology, UTHealth, Houston, TX
*Purpose: A renal biopsy, the gold standard for the diagnosis of antibody mediated rejection (ABMR) in transplant recipients, is invasive and may be associated with…
2019 American Transplant Congress
Impact of a Novel Digital Medicine Program on Adherence and Utilization in Pediatric Transplant Patients
S. Sullivan¹, K. N. Triplett¹, C. Sacks², M. Tran², D. M. Desai³
¹Solid Organ Transplant, Children's Medical Center, Dallas, Dallas, TX, ²Proteus Digital Health, Redwood City, CA, ³Transplant Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, TX
*Purpose: Purpose: Optimal allograft function and long-term graft survival depends on many factors, including adherence to a complex medication regimen. Methods of measuring adherence are…
2019 American Transplant Congress
HLA-DR Upregulation in Pediatric Kidney Transplant Biopsies
O. Moussa, S. Self, E. Bruner, K. Twombley
Medical University of South Carolina, Charleston, SC
*Purpose: Renal tubular epithelial cells do not typically express human leukocyte antigen DR (HLA-DR). It’s expression has been associated with different types of tubular injury…
2019 American Transplant Congress
Development and Implementation of a Pediatric Transplant Consortium
K. Soltys¹, S. K. Rassmussen², J. Squires³, R. Sindhi¹, S. Pelletier², K. Brayman², M. Angelis⁴, T. Chin⁴, R. Teaster², J. Oberholzer², R. Gonzalez-Peralta⁵, B. Friedman⁴, D. Hupp⁶, M. Mendoza⁷, P. A. Eicker⁶, J. Middleton⁷, G. Mazariegos¹
¹Transplant Surgery, Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Charles O. Strickler Transplant Center, University of Virginia, Charlottesville, VA, ³Hepatology, Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ⁴AdventHealth Transplant Institute, Florida Hospital, Orlando, FL, ⁵AdventHealth for Children, Florida Hospital, Orlando, FL, ⁶Nursing, Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ⁷Hepatology, University of Virginia, Charlottesville, VA
*Purpose: Access to pediatric liver transplant expertise varies nationally and variability in practice leads to potential suboptimal organ utilization and outcomes. A multi-institutional collaborative was…