Articles tagged "Pediatric"

2020 American Transplant Congress
Renal Function Parameters Improve PELDs Prediction of 90-day Death or Deterioration
L. Thalji¹, N. Thalji², D. Haile¹, J. Heimbach², S. Ibrahim³, P. Kamath⁴, D. Kor¹
¹Anesthesiology, Mayo Clinic, Rochester, MN, ²Surgery, Mayo Clinic, Rochester, MN, ³Pediatric Gastroenterology, Mayo Clinic, Rochester, MN, ⁴Gastroenterology, Mayo Clinic, Rochester, MN
*Purpose: Reliance upon exception points to prioritize children for liver transplantation (LT) stems from concerns that the Pediatric End-Stage Liver Disease (PELD) score underestimates mortality.…
2020 American Transplant Congress
Pediatric Renal Transplant after Intestinal Transplant – Technical Challenges and Outcomes
A. Amin, B. Emmanuel, Y. Chang, G. Bond, A. Khanna, K. Soltys, R. Sindhi, A. Tevar, A. Humar, G. Mazariegos, A. Ganoza
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: There is no data in the literature about outcomes of pediatric intestinal transplant (IT) recipients, who require renal transplant after intestinal transplant (RTAIT). The…
2020 American Transplant Congress
Recruitment in the Pediatric Heart Transplant TEAMMATE Trial: Observed vs. Expected
K. P. Daly, L. A. Sleeper, L. J. Addonizio, J. C. Alejos, S. Auerbach, M. J. Bock, A. Butto, W. F. Carlo, C. Castleberry, W. J. Dreyer, B. Feingold, J. M. Lamour, E. L. Albers, S. A. Hollander, G. L. Klein, A. Lal, E. Pahl, D. Peng, A. R. Punnoose, J. W. Rossano, T. D. Ryan, J. Su, D. L. Sutcliffe, S. Zangwill, C. S. Almond
TEAMMATE Trial Investigators, Boston, MA
*Purpose: The TEAMMATE (Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients using the MATE Score) Trial is the first multicenter effort to address key scientific…
2020 American Transplant Congress
Evaluation of Risk Factors and Outcomes for Hepatic Artery Thrombosis Post Pediatric Liver Transplantation
J. T. McDonald¹, T. Miloh², K. Thompson¹, K. Hosek³, J. Goss¹, C. Kennedy³
¹Baylor College of Medicine, Houston, TX, ²Miami Transplant Institute, Miami, FL, ³Texas Children's Hospital, Houston, TX
*Purpose: Evaluate which transplantation parameters have an association with HAT, as well as to determine the success rate of HAT intervention at TCH since 2011.*Methods:…
2020 American Transplant Congress
Sex and ABO Antibodies: High-Level Natural ABO Antibody Production and IgM to IgG Class Switch in Female vs. Male Mice
B. Anjum, B. Motyka, I. Adam, J. Fersovich, M. Sulzer, J. Pearcey, K. Tao, L. J. West
Dept Pediatrics, Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada
*Purpose: ABO histo-blood group incompatibility is a barrier in solid organ transplant due to the presence of ‘natural’ preformed ABO antibodies. However, ABO-incompatible (ABOi) heart…
2020 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies are Associated with Younger Age and Renal Dysfunction in Pediatric Kidney Transplantation
M. Pearl¹, E. T. Chambers², A. Kirk², R. Garro³, B. L. Warshaw³, P. Grimm⁴, R. Ettenger¹, E. Reed¹
¹UCLA, Los Angeles, CA, ²Duke, Durham, NC, ³Emory, Atlanta, GA, ⁴Stanford, Stanford, CA
*Purpose: The significance of non-HLA antibodies in renal transplantation remains unclear. In small single center retrospective studies, angiotensin II type 1 receptor antibody (AT1R-Ab) has…
2020 American Transplant Congress
Induction Immunosuppression in Primary Pediatric Liver Transplant Recipients
T. Shaker¹, K. Ramanathan¹, S. Riad², D. Vock³, S. Chinnakotla¹
¹Surgery, Division of Transplantation, University of Minnesota, Minneapolis, MN, ²Division of Renal Diseases and Hypertension, University of Minnesota, Minneapolis, MN, ³Biostatistics, University of Minnesota, Minneapolis, MN
*Purpose: Induction immunosuppression for pediatric liver transplants varies widely among centers. We sought to evaluate the impact of different induction regimens on patient and graft…
2020 American Transplant Congress
Validity and Utility of Urinary CXCL10/Cr Monitoring in Pediatric Kidney Transplant Recipients
T. Blydt-Hansen¹, A. Sharma², I. Gibson², C. Weibe², A. Sharma³, V. Langlois⁴, C. Teoh⁴, D. Rush², P. Nickerson², D. Wishart⁵, J. Ho²
¹University of British Columbia, Vancouver, BC, Canada, ²University of Manitoba, Winnipeg, MB, Canada, ³University of Western Ontaria, London, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada, ⁵University of Alberta, Edmonton, AB, Canada
*Purpose: Effective post-transplant monitoring is hampered by a lack of effective biomarkers. We sought to validate the utility of urinary CXCL10/Cr monitoring of rejection in…
2020 American Transplant Congress
Use of Donor-Derived Cell-Free DNA Assay to Monitor Treatment Response to Allograft Rejection in Pediatric Renal Transplant Recipients
J. Steggerda¹, H. Phan Pizzo², J. Garrison², X. Zhang³, M. Haas⁴, I. Kim¹, S. Jordan¹, D. Puliyanda²
¹Comprehensive Transplant Center, Cedars Sinai Medical Center, West Hollywood, CA, ²Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA, ³HLA Laboratory, Cedars-Sinai Med Center, West Hollywood, CA, ⁴Pathology, Cedars Sinai Medical Center, West Hollywood, CA
*Purpose: Acute rejection (AR) accounts for 13%-21% of graft failure in pediatrics (peds), with the number, severity, and response to treatment being a major determinant…
2020 American Transplant Congress
Extracorporeal Membrane Oxygenation in Pediatric Liver Transplantation
I. A. Ziogas¹, W. R. Johnson¹, C. Thurm², M. Hall², L. K. Matsuoka¹, M. I. Montenovo¹, M. D. Bacchetta¹, J. Godown³, S. P. Alexopoulos¹
¹Vanderbilt University Medical Center, Nashville, TN, ²Children's Hospital Association, Lenexa, KS, ³Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN
*Purpose: Extracorporeal membrane oxygenation (ECMO) can be used for oxygen preservation and hemodynamic support in case of circulatory or respiratory failure. Although the role of…