Articles tagged "Pediatric"

2022 American Transplant Congress
Urine-based Assay For Detection Of Acute Rejection In Pediatric Kidney Transplant Recipients
C. Crane¹, K. Zeeb², E. Phebus², C. Benavides², W. Wong³, E. Ingulli²
¹UCSD/Rady Children's Hospital, San Diego, CA, ²UCSD Rady Children's Hospital, San Diego, CA, ³Massachusetts General Brigham, Boston, MA
*Purpose: Biomarkers such as donor-derived cell free DNA (cfDNA) and gene expression profiling are utilized in adult transplant patients (pts), but these tests lack sensitivity…
2022 American Transplant Congress
Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Practice Patterns, Report from the Paramour “Pediatric Renal AMR Outcomes” Study
N. Hayde¹, K. Twombley², I. Ashoor³, R. Engen⁴, L. Harshman⁵, R. Zahr⁶, C. Peterson⁷, S. McEwen⁸, A. Jain⁹, R. Garro¹⁰, M. Kallash¹¹, A. Mansuri¹², D. Puliyanda¹³
¹Montefiore Medical Center, Bronx, NY, ²Medical University of South Carolina, Charleston, SC, ³LCMCHealth, New Orleans, LA, ⁴Pediatrics, University of Wisconsin Madison, Madison, WI, ⁵University of Iowa Children's Hospital, Iowa City, IA, ⁶Le Bonheur Children's Hospital, Nashville, TN, ⁷University of Utah, Salt Lake City, UT, ⁸University of Minnesota, Minneapolis, MN, ⁹Wayne State, Troy, MI, ¹⁰Emory Universtiy, Atlanta, GA, ¹¹The Ohio State, Columbus, OH, ¹²Augusta University Medical Center, Augusta, GA, ¹³Cedars-Sinai Med Ctr, West Hollywood, CA
*Purpose: There is insufficient data on children with AMR in the literature, and the optimal therapy for AMR is not well defined. We aim to…
2022 American Transplant Congress
Donor-Derived Cell-Free DNA as a Biomarker of T Cell Mediated Rejection in Pediatric Kidney Transplant Patients
R. Dandamudi¹, S. Federman², R. Woodward², S. Dholakia², L. Walther¹, V. Dharnidharka¹
¹Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, ²CareDx, Brisbane, CA
*Purpose: T-cell-mediated rejection (TCMR) is a major cause of kidney allograft failure which requires kidney biopsy for a definitive diagnosis. Donor-derived cell-free DNA (dd-cfDNA) is…
2022 American Transplant Congress
Why is Adolescent Waitlist Mortality Higher for Status 1A Girls?
J. Foutz¹, E. Hsu², S. Noreen³, M. Cafarella⁴, J. Pomposelli⁵, S. Biggins⁶, J. Reyes⁶, E. Perito⁷
¹Research, United Network for Organ Sharing, Richmond, VA, ²Seattle Children's Hospital, Seattle, WA, ³United Network for Organ Sharing, Richmond, VA, ⁴Policy and Community Relations, United Network for Organ Sharing, Richmond, VA, ⁵University of Colorado, Aurora, CO, ⁶University of Washington, Seattle, WA, ⁷UCSF, San Francisco, CA
*Purpose: Although adolescent pediatric liver transplant candidates are a vulnerable population, they are often excluded from analyses due to small sample size and assignment of…
2022 American Transplant Congress
Financial Barriers Experienced During the Transplant Process by Caregivers of Children with End Stage Kidney Disease
R. Goldfarb Terry¹, A. Edwards¹, U. Parlin², A. Chung¹, S. Amaral¹
¹Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Known socioeconomic disparities in transplant referral and evaluation exist in adults with end-stage kidney disease, but little is known about the financial burden that…
2022 American Transplant Congress
Genotype and Phenotype Analysis and the Transplantation Strategy in Children with Uremia Caused by Nephronophthisis
J. Li, H. Zhang, X. Su, J. Li, S. Wu, W. Wu, L. Ling, Q. Fu, C. Wu, L. Liu, C. Wang
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Nephronophthisis- related ciliopathies(NPHP- RC), as an important cause of children's end-stage renal disease(ESRD), has strong genotype and phenotype heterogeneity, and the transplantation strategy of…
2022 American Transplant Congress
Evaluation of the Significance of Isolated C4d Staining without Histological Evidence of Rejection on Kidney Biopsies After ABO-Compatible Transplantation in Pediatric Recipients
C. Duneton¹, M. Rabant², J. Duong-Van-Huyen², V. Baudouin¹, E. Cheyssac¹, O. Boyer³, J. Hogan¹
¹Pediatric Nephrology, Robert Debré Hospital, APHP, Paris, France, ²Pathology, Necker Hospital, Paris, France, ³Pediatric Nephrology, Necker Hospital, Paris, France
*Purpose: C4d staining in peritubular capillaries has been part of ABMR Banff definition since 2003. Despite relatively high specificity, c4d staining shows limited sensitivity, and…
2022 American Transplant Congress
Changes in Diastolic Function and Cardiac Geometry After Pediatric Kidney Transplant: A Longitudinal Study
K. Sgambat¹, S. Clauss², A. Moudgil¹
¹Nephrology, Children's National Hospital, Washington DC, DC, ²Cardiology, Children's National Hospital, Washington DC, DC
*Purpose: Kidney transplant recipients are at increased risk for cardiovascular disease but systolic function is often preserved and may not reveal cardiac dysfunction until it…
2022 American Transplant Congress
Cytomegalovirus Prophylaxis in Pediatric Liver Transplantation: A Comparison of Strategies Across the SPLIT Consortium
E. D. Knackstedt¹, S. G. Anderson², R. Anand², J. Mitchell², J. Bucuvalas³, L. Danziger-Isakov⁴
¹Univ of Utah/Primary Children's Hosp, SLC, UT, ²Emmes, Rockville, MD, ³Icahn School of Med at Mount Sinai, New York City, NY, ⁴Cincinnati Children's Hosp Med Ctr, Cincinnati, OH
*Purpose: To compare the effectiveness of short (180d) cytomegalovirus (CMV) prophylaxis in pediatric liver transplantation (pLTX).*Methods: A prospective cohort study of primary pLTX (≤18 yrs…
2022 American Transplant Congress
Finding Living Donors on Social Media for Pediatric Kidney and Liver Transplant Candidates
D. Yoeli¹, S. Mathai², J. Kaar³, C. Mata³, A. Feldman⁴, M. Bock⁵, W. Jackson⁶, M. Adams¹
¹Surgery, University of Colorado Anschutz Medical, Aurora, CO, ²School of Medicine, University of Colorado Anschutz Medical, Aurora, CO, ³Center for Research in Outcomes for Children's Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, ⁴Section of Gastroenterology, Hepatology, and Nutrition, Digestive Health Institute, Children's Hospital Colorado, Aurora, CO, ⁵Department of Pediatric Nephrology, Children's Hospital Colorado, Aurora, CO, ⁶Hepatology, University of Colorado Anschutz Medical Campus, Aurora, CO
*Purpose: Living donor kidney and liver transplantation are associated with superior outcomes in children. We hypothesized that social media can be a valuable tool to…